Literature DB >> 2555569

Infectious cDNA clones of the DA strain of Theiler's murine encephalomyelitis virus.

R P Roos1, S Stein, Y Ohara, J L Fu, B L Semler.   

Abstract

The DA strain and other members of the TO subgroup of Theiler's murine encephalomyelitis viruses cause a persistent demyelinating infection, whereas the GDVII strain and other GDVII subgroup strains cause an acute lethal polioencephalomyelitis. We generated an infectious DA cDNA clone inserted into a transcription vector. Virus derived from transfection of transcripts produced a demyelinating disease indistinguishable from that of wild-type virus. The infectious clone provides a critical reagent for the production of interstrain recombinant viruses to help identify genetic loci responsible for the biological activities of the strains.

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Year:  1989        PMID： 2555569      PMCID： PMC251223          DOI： 10.1128/JVI.63.12.5492-5496.1989

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

1.  Polyprotein processing of Theiler's murine encephalomyelitis virus.

Authors:  R P Roos; W P Kong; B L Semler
Journal:  J Virol       Date:  1989-12       Impact factor: 5.103

2.  Molecular cloning of the complete genome of strain GDVII of Theiler's virus and production of infectious transcripts.

Authors:  F Tangy; A McAllister; M Brahic
Journal:  J Virol       Date:  1989-03       Impact factor: 5.103

3.  In vitro molecular genetics as a tool for determining the differential cleavage specificities of the poliovirus 3C proteinase.

Authors:  M F Ypma-Wong; B L Semler
Journal:  Nucleic Acids Res       Date:  1987-03-11       Impact factor: 16.971

4.  Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase.

Authors:  S van der Werf; J Bradley; E Wimmer; F W Studier; J J Dunn
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

5.  Neutralizing monoclonal antibodies to Theiler's murine encephalomyelitis viruses.

Authors:  S Nitayaphan; M M Toth; R P Roos
Journal:  J Virol       Date:  1985-02       Impact factor: 5.103

6.  Trypsin-sensitive neutralization site on VP1 of Theiler's murine encephalomyelitis viruses.

Authors:  Y Ohara; A Senkowski; J L Fu; L Klaman; J Goodall; M Toth; R P Roos
Journal:  J Virol       Date:  1988-09       Impact factor: 5.103

7.  Persistent Theiler's murine encephalomyelitis virus infection in mice depends on plaque size.

Authors:  H L Lipton
Journal:  J Gen Virol       Date:  1980-01       Impact factor: 3.891

8.  Mapping of sequences required for mouse neurovirulence of poliovirus type 2 Lansing.

Authors:  N La Monica; C Meriam; V R Racaniello
Journal:  J Virol       Date:  1986-02       Impact factor: 5.103

9.  Theiler's murine encephalomyelitis virus group includes two distinct genetic subgroups that differ pathologically and biologically.

Authors:  Y Lorch; A Friedmann; H L Lipton; M Kotler
Journal:  J Virol       Date:  1981-11       Impact factor: 5.103

10.  Molecular cloning and sequence determination of DA strain of Theiler's murine encephalomyelitis viruses.

Authors:  Y Ohara; S Stein; J L Fu; L Stillman; L Klaman; R P Roos
Journal:  Virology       Date:  1988-05       Impact factor: 3.616
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  50 in total

1.  L* protein of Theiler's murine encephalomyelitis virus is required for virus growth in a murine macrophage-like cell line.

Authors:  M Obuchi; J Yamamoto; T Odagiri; M N Uddin; H Iizuka; Y Ohara
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

2.  Influence of the Theiler's virus L* protein on macrophage infection, viral persistence, and neurovirulence.

Authors:  O van Eyll; T Michiels
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

3.  Epitope-tagged L* protein of Theiler's murine encephalomyelitis virus is expressed in the central nervous system in the acute phase of infection.

Authors:  Kunihiko Asakura; Harunobu Murayama; Toshiki Himeda; Yoshiro Ohara
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

4.  Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease.

Authors:  Ikuo Tsunoda; Jane E Libbey; Robert S Fujinami
Journal:  J Neurovirol       Date:  2012-03-09       Impact factor: 2.643

5.  Different strains of Theiler's murine encephalomyelitis virus antagonize different sites in the type I interferon pathway.

Authors:  Spyridon Stavrou; Zongdi Feng; Stanley M Lemon; Raymond P Roos
Journal:  J Virol       Date:  2010-07-07       Impact factor: 5.103

6.  Alternative translation initiation site in the DA strain of Theiler's murine encephalomyelitis virus.

Authors:  W P Kong; R P Roos
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

7.  Conservation of RNA-protein interactions among picornaviruses.

Authors:  S L Dildine; B L Semler
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

8.  Construction of rubella virus genome-length cDNA clones and synthesis of infectious RNA transcripts.

Authors:  C Y Wang; G Dominguez; T K Frey
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

9.  Theiler's virus as a vector for foreign gene delivery.

Authors:  L Zhang; S Sato; J I Kim; R P Roos
Journal:  J Virol       Date:  1995-05       Impact factor: 5.103

10.  Nucleotide sequence of classical swine fever virus strain Alfort/187 and transcription of infectious RNA from stably cloned full-length cDNA.

Authors:  N Ruggli; J D Tratschin; C Mittelholzer; M A Hofmann
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103
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