Literature DB >> 2552768

The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.

D J Schrier1, M A Adamchak, A M Boctor, C R Kostlan, D L Flynn, J H Jordan, M E Lesch, G C Okonkwo.   

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Year:  1989        PMID： 2552768     DOI： 10.1007/BF01972831

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


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  5 in total

1.  Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.

Authors:  C A WINTER; E A RISLEY; G W NUSS
Journal:  Proc Soc Exp Biol Med       Date:  1962-12

2.  The anti=inflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide).

Authors:  G DiPasquale; C Rassaert; R Richter; P Welaj; J Gingold; R Singer
Journal:  Agents Actions       Date:  1975-08

3.  Leukotriene B4, polymorphonuclear leukocytes and inflammatory exudates in the rat.

Authors:  A W Ford-Hutchinson; G Brunet; P Savard; S Charleson
Journal:  Prostaglandins       Date:  1984-07

4.  Adjuvant polyarthritis. IV. Induction by a synthetic adjuvant: immunologic, histopathologic, and other studies.

Authors:  Y H Chang; C M Pearson; C Abe
Journal:  Arthritis Rheum       Date:  1980-01

5.  Comparison in rats of the anti-inflammatory and gastric irritant effects of etodolac with several clinically effective anti-inflammatory drugs.

Authors:  R R Martel; J Klicius
Journal:  Agents Actions       Date:  1982-07
  5 in total
  1 in total

1.  Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability.

Authors:  S Wong; S J Lee; M R Frierson; J Proch; T A Miskowski; B S Rigby; S J Schmolka; R W Naismith; D C Kreutzer; R Lindquist
Journal:  Agents Actions       Date:  1992-09
  1 in total

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