Literature DB >> 255090

Ricin and modeccin do not inhibit the elongation factor 1-dependent binding of aminoacyl-tRNA to ribosomes.

S Sperti, L Montanaro.   

Abstract

Ricin and modeccin do not affect the total number of ribosomes to which phenylalanyl-tRNA becomes bound in the EF 1-dependent reaction. Previous inconsistencies resulted from the use of the nitrocellulose-filter technique, which overestimates the number of control ribosomes engaged in the binding reaction if trace amounts of EF 2 contaminate the ribosomal preparations.

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Year:  1979        PMID： 255090      PMCID： PMC1186501          DOI： 10.1042/bj1780233

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  18 in total

1.  Effect of modeccin on the steps of peptide-chain elongation.

Authors:  L Montanaro; S Sperti; M Zamboni; M Denaro; G Testoni; A Gasperi-Campani; F Stirpe
Journal:  Biochem J       Date:  1978-11-15       Impact factor: 3.857

2.  Relationship between elongation factor I- and elongation factor II- dependent guanosine triphosphatase activities of ribosomes. Inhibition of both activities by ricin.

Authors:  S Sperti; L Montanaro; A Mattioli; G Testoni
Journal:  Biochem J       Date:  1975-06       Impact factor: 3.857

3.  Inhibition by ricin of protein synthesis in vitro. Inhibition of the binding of elongation factor 2 and of adenosine diphosphate-ribosylated elongation factor 2 to ribosomes.

Authors:  L Montanaro; S Sperti; A Mattioli; G Testoni; F Stirpe
Journal:  Biochem J       Date:  1975-01       Impact factor: 3.857

4.  Inhibition by ricin of protein synthesis in vitro: 60 S ribosomal subunit as the target of the toxin.

Authors:  S Sperti; L Montanaro; A Mattioli; F Stirpe
Journal:  Biochem J       Date:  1973-11       Impact factor: 3.857

5.  Effect of development on the translation of messenger RNA in Artemia salina embryos.

Authors:  J M Sierra; D Meier; S Ochoa
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

6.  Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma.

Authors:  G L Nicolson; J Blaustein; M E Etzler
Journal:  Biochemistry       Date:  1974-01-01       Impact factor: 3.162

7.  On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit.

Authors:  S Benson; S Olsnes; A Pihl; J Skorve; A K Abraham
Journal:  Eur J Biochem       Date:  1975-11-15

8.  A supernatant factor involved in initiation complex formation with eukaryotic ribosomes.

Authors:  M Zasloff; S Ochoa
Journal:  Proc Natl Acad Sci U S A       Date:  1971-12       Impact factor: 11.205

9.  Site of action of ricin on the ribosome.

Authors:  C Fernández-Puentes; L Carrasco; D Vázquez
Journal:  Biochemistry       Date:  1976-10-05       Impact factor: 3.162

10.  The binding of tritiated elongation-factors 1 and 2 to ribosomes from Krebs II mouse ascites-tumore cells. The influence of various antibiotics and toxins.

Authors:  R D Nolan; H Grasmuk; J Drews
Journal:  Eur J Biochem       Date:  1976-04-15
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  2 in total

1.  Effect of alpha-sarcin and ribosome-inactivating proteins on the interaction of elongation factors with ribosomes.

Authors:  M Brigotti; F Rambelli; M Zamboni; L Montanaro; S Sperti
Journal:  Biochem J       Date:  1989-02-01       Impact factor: 3.857

2.  Effect of the antibiotic purpuromycin on cell-free protein-synthesizing systems.

Authors:  F Rambelli; M Brigotti; M Zamboni; M Denaro; L Montanaro; S Sperti
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857
  2 in total

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