Literature DB >> 2542569

Structure of the Marek's disease virus BamHI-H gene family: genes of putative importance for tumor induction.

G Bradley1, M Hayashi, G Lancz, A Tanaka, M Nonoyama.   

Abstract

The BamHI H fragment of Marek's disease virus (MDV), which has been hypothesized to contain a tumor-inducing gene, was partially sequenced and analyzed for transcriptional activity. Transcription of several RNAs was found to initiate within BamHI-H, with the major transcripts initiating on either side of a putative MDV origin of lytic replication. A 1.8-kilobase gene family found to be produced only by pathogenic MDV was detected, and its transcription map was produced. It is hypothesized that the 1.8-kilobase gene family is directly associated with the tumorigenic potential of MDV.

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Year:  1989        PMID： 2542569      PMCID： PMC250719     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  33 in total

1.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

2.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

Review 3.  The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.

Authors:  S K Hanks; A M Quinn; T Hunter
Journal:  Science       Date:  1988-07-01       Impact factor: 47.728

4.  Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors:  G K McMaster; G G Carmichael
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

5.  A DNA fragment of Herpes simplex 2 and its transcription in human cervical cancer tissue.

Authors:  N Frenkel; B Roizman; E Cassai; A Nahmias
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

6.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

7.  Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1.

Authors:  R Duff; F Rapp
Journal:  J Virol       Date:  1973-08       Impact factor: 5.103

8.  Size and composition of Marek's disease virus deoxyribonucleic acid.

Authors:  L F Lee; E D Kieff; S L Bachenheimer; B Roizman; P G Spear; B R Burmester; K Nazerian
Journal:  J Virol       Date:  1971-03       Impact factor: 5.103

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162
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  43 in total

1.  The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus.

Authors:  L F Lee; P Wu; D Sui; D Ren; J Kamil; H J Kung; R L Witter
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

2.  The genome of a very virulent Marek's disease virus.

Authors:  E R Tulman; C L Afonso; Z Lu; L Zsak; D L Rock; G F Kutish
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

3.  Characterization of a very virulent Marek's disease virus mutant expressing the pp38 protein from the serotype 1 vaccine strain CVI988/Rispens.

Authors:  Lucy F Lee; Xiaoping Cui; Zhizhong Cui; Isabel Gimeno; Blanca Lupiani; Sanjay M Reddy
Journal:  Virus Genes       Date:  2005-08       Impact factor: 2.332

4.  Marek's disease virus unique genes pp38 and pp24 are essential for transactivating the bi-directional promoters for the 1.8 kb mRNA transcripts.

Authors:  Jiabo Ding; Zhizhong Cui; Lucy F Lee
Journal:  Virus Genes       Date:  2007-07-06       Impact factor: 2.332

5.  Isolation and characterization of cDNAs from BamHI-H gene family RNAs associated with the tumorigenicity of Marek's disease virus.

Authors:  F Peng; G Bradley; A Tanaka; G Lancz; M Nonoyama
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

6.  Novel DNA binding specificities of a putative herpesvirus bZIP oncoprotein.

Authors:  Z Qian; P Brunovskis; L Lee; P K Vogt; H J Kung
Journal:  J Virol       Date:  1996-10       Impact factor: 5.103

7.  Recombinant Marek's disease virus (MDV)-derived lymphoblastoid cell lines: regulation of a marker gene within the context of the MDV genome.

Authors:  M S Parcells; R L Dienglewicz; A S Anderson; R W Morgan
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

8.  Loss of Marek's disease virus tumorigenicity is associated with truncation of RNAs transcribed within BamHI-H.

Authors:  G Bradley; G Lancz; A Tanaka; M Nonoyama
Journal:  J Virol       Date:  1989-10       Impact factor: 5.103

9.  Identification of an immediate-early gene in the Marek's disease virus long internal repeat region which encodes a unique 14-kilodalton polypeptide.

Authors:  Y Hong; P M Coussens
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

10.  The construction and characterization of the bi-directional promoter between pp38 gene and 1.8-kb mRNA transcripts of Marek's disease viruses.

Authors:  Ruiai Chen; Jiabo Ding; Bin Wang
Journal:  Virol J       Date:  2009-11-30       Impact factor: 4.099
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