Jayeon Kim1, Jennifer E Mersereau. 1. Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of North Carolina at Chapel Hill, 4001 Old Clinic Building, CB 7570, Chapel Hill, NC, 27599-7570, USA.
Abstract
PURPOSE: The purpose of the study was to investigate the association between patients' decision-making about fertility preservation (FP) and time between cancer diagnosis and FP consultation in young female cancer survivors. METHODS: This is a pilot survey study of women aged 18-43 years seen for FP consultation between April 2009 and December 2010. RESULTS: Among 52 women who completed the survey, 15 (29 %) had their FP consultation more than 2 weeks after their cancer diagnosis (late referral group) and 37 (71 %) were within 2 weeks of their cancer diagnosis (early referral group). In univariate analysis, the only difference between the late referral and early referral groups was a higher decisional conflict scale (DCS) in late referral group (p = 0.04). In multivariable analysis, late referral group was more likely to have high DCS (>35) compared to early referral group (odds ratio 4.8, 95 % confidence interval 1.5, 21.6) after adjusting for age, center, and type of cancer. CONCLUSION: Early referral to a fertility specialist can help patients make better decision about FP. This is the first study to suggest that early referral is important in patients' decision-making process about FP treatment. Our finding supports the benefit of early referral in patients who are interested in FP which is consistent with prior studies about FP referral patterns.
PURPOSE: The purpose of the study was to investigate the association between patients' decision-making about fertility preservation (FP) and time between cancer diagnosis and FP consultation in young female cancer survivors. METHODS: This is a pilot survey study of women aged 18-43 years seen for FP consultation between April 2009 and December 2010. RESULTS: Among 52 women who completed the survey, 15 (29 %) had their FP consultation more than 2 weeks after their cancer diagnosis (late referral group) and 37 (71 %) were within 2 weeks of their cancer diagnosis (early referral group). In univariate analysis, the only difference between the late referral and early referral groups was a higher decisional conflict scale (DCS) in late referral group (p = 0.04). In multivariable analysis, late referral group was more likely to have high DCS (>35) compared to early referral group (odds ratio 4.8, 95 % confidence interval 1.5, 21.6) after adjusting for age, center, and type of cancer. CONCLUSION: Early referral to a fertility specialist can help patients make better decision about FP. This is the first study to suggest that early referral is important in patients' decision-making process about FP treatment. Our finding supports the benefit of early referral in patients who are interested in FP which is consistent with prior studies about FP referral patterns.
Authors: Ursula Balthazar; Allison M Deal; Marc A Fritz; Laxmi A Kondapalli; Ja Yeon Kim; Jennifer E Mersereau Journal: Hum Reprod Date: 2012-06-06 Impact factor: 6.918
Authors: K A Metcalfe; A Poll; A O'Connor; S Gershman; S Armel; A Finch; R Demsky; B Rosen; S A Narod Journal: Clin Genet Date: 2007-09 Impact factor: 4.438
Authors: Jamie C Brehaut; Annette M O'Connor; Timothy J Wood; Thomas F Hack; Laura Siminoff; Elisa Gordon; Deb Feldman-Stewart Journal: Med Decis Making Date: 2003 Jul-Aug Impact factor: 2.583
Authors: Thomas F Hack; Tom Pickles; J Dean Ruether; Lorna Weir; Barry D Bultz; John Mackey; Lesley F Degner Journal: Psychooncology Date: 2010-06 Impact factor: 3.894
Authors: Mary Peavey; Sara Arian; William Gibbons; Karen Lu; David Gershenson; Terri Woodard Journal: J Adolesc Young Adult Oncol Date: 2016-11-15 Impact factor: 2.223
Authors: R Anguzu; R Cusatis; N Fergestrom; A Cooper; K D Schoyer; J B Davis; J Sandlow; K E Flynn Journal: Hum Reprod Date: 2020-03-27 Impact factor: 6.918
Authors: Jayeon Kim; Jennifer E Mersereau; H Irene Su; Brian W Whitcomb; Vanessa L Malcarne; Jessica R Gorman Journal: Support Care Cancer Date: 2016-03-04 Impact factor: 3.603
Authors: Elizabeth J N Miller; Lisa M Cookingham; Teresa K Woodruff; Ginny L Ryan; Karen M Summers; Laxmi A Kondapalli; Divya K Shah Journal: Fertil Res Pract Date: 2017-07-04