Literature DB >> 25419068

Complete radiologic and metabolic response of colorectal liver metastasis after neoadjuvant chemotherapy: to resect or not?

Ramakrishnan A Seshadri1, Saurab Gupta1.   

Abstract

Resection of liver metastasis has led to improved survival in selected patients with colorectal cancer. Neoadjuvant chemotherapy in this setting has many advantages. Positron emission tomography scan (PET) is useful in monitoring the response of the liver metastases to chemotherapy. Neoadjuvant chemotherapy can cause a complete response of the liver metastasis in some patients. We report a complete radiological and metabolic response of a liver metastasis following neoadjuvant chemotherapy and discuss the therapeutic implications and options in such a situation.

Entities:  

Keywords:  Colorectal liver metastasis; Complete response; Neoadjuvant chemotherapy; PET-CT

Year:  2014        PMID： 25419068      PMCID： PMC4235861          DOI： 10.1007/s13193-014-0330-7

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN： 0975-7651


  13 in total

1.  Hepatic resection: the last surgical frontier for colorectal cancer.

Authors:  Nicholas J Petrelli; James Abbruzzese; Paul Mansfield; Bruce Minsky
Journal:  J Clin Oncol       Date:  2005-07-10       Impact factor: 44.544

2.  Positron emission tomography with F-18 fluorodeoxyglucose in evaluating colorectal hepatic metastasis down-staged by chemotherapy.

Authors:  Shinichiro Takahashi; Yoshihumi Kuroki; Katsuhiro Nasu; Shigeru Nawano; Masaru Konishi; Toshio Nakagohri; Naoto Gotohda; Norio Saito; Taira Kinoshita
Journal:  Anticancer Res       Date:  2006 Nov-Dec       Impact factor: 2.480

3.  Disappearing colorectal liver metastases after chemotherapy: should we be concerned?

Authors:  Mark G van Vledder; Mechteld C de Jong; Timothy M Pawlik; Richard D Schulick; Luis A Diaz; Michael A Choti
Journal:  J Gastrointest Surg       Date:  2010-09-14       Impact factor: 3.452

4.  ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making.

Authors:  H J Schmoll; E Van Cutsem; A Stein; V Valentini; B Glimelius; K Haustermans; B Nordlinger; C J van de Velde; J Balmana; J Regula; I D Nagtegaal; R G Beets-Tan; D Arnold; F Ciardiello; P Hoff; D Kerr; C H Köhne; R Labianca; T Price; W Scheithauer; A Sobrero; J Tabernero; D Aderka; S Barroso; G Bodoky; J Y Douillard; H El Ghazaly; J Gallardo; A Garin; R Glynne-Jones; K Jordan; A Meshcheryakov; D Papamichail; P Pfeiffer; I Souglakos; S Turhal; A Cervantes
Journal:  Ann Oncol       Date:  2012-10       Impact factor: 32.976

5.  Complete response of colorectal liver metastases after chemotherapy: does it mean cure?

Authors:  Stéphane Benoist; Antoine Brouquet; Christophe Penna; Catherine Julié; Mostafa El Hajjam; Sophie Chagnon; Emmanuel Mitry; Philippe Rougier; Bernard Nordlinger
Journal:  J Clin Oncol       Date:  2006-08-20       Impact factor: 44.544

6.  Recent chemotherapy reduces the sensitivity of [18F]fluorodeoxyglucose positron emission tomography in the detection of colorectal metastases.

Authors:  Timothy Akhurst; Tara J Kates; Madhu Mazumdar; Henry Yeung; Elyn R Riedel; Bryan M Burt; Leslie Blumgart; William Jarnagin; Steven M Larson; Yuman Fong
Journal:  J Clin Oncol       Date:  2005-12-01       Impact factor: 44.544

7.  A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

Authors:  Richard M Goldberg; Daniel J Sargent; Roscoe F Morton; Charles S Fuchs; Ramesh K Ramanathan; Stephen K Williamson; Brian P Findlay; Henry C Pitot; Steven R Alberts
Journal:  J Clin Oncol       Date:  2003-12-09       Impact factor: 44.544

8.  Chemotherapy-induced normalization of FDG uptake by colorectal liver metastases does not usually indicate complete pathologic response.

Authors:  Marcus C B Tan; David C Linehan; William G Hawkins; Barry A Siegel; Steven M Strasberg
Journal:  J Gastrointest Surg       Date:  2007-07-11       Impact factor: 3.452

Review 9.  Surgical management of disappearing colorectal liver metastases.

Authors:  D A Bischof; B M Clary; S K Maithel; T M Pawlik
Journal:  Br J Surg       Date:  2013-08-16       Impact factor: 6.939

Review 10.  Preoperative imaging of colorectal liver metastases after neoadjuvant chemotherapy: a meta-analysis.

Authors:  Charlotte S van Kessel; Constantinus F M Buckens; Maurice A A J van den Bosch; Maarten S van Leeuwen; Richard van Hillegersberg; Helena M Verkooijen
Journal:  Ann Surg Oncol       Date:  2012-03-07       Impact factor: 5.344
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