Literature DB >> 25417146

Geroscience: linking aging to chronic disease.

Brian K Kennedy1, Shelley L Berger2, Anne Brunet3, Judith Campisi4, Ana Maria Cuervo5, Elissa S Epel6, Claudio Franceschi7, Gordon J Lithgow8, Richard I Morimoto9, Jeffrey E Pessin10, Thomas A Rando11, Arlan Richardson12, Eric E Schadt13, Tony Wyss-Coray14, Felipe Sierra15.   

Abstract

Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches. Given that the elderly population is dramatically increasing and that aging is the greatest risk factor for a majority of chronic diseases driving both morbidity and mortality, it is critical to expand geroscience research directed at extending human healthspan.

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Year:  2014        PMID： 25417146      PMCID： PMC4852871          DOI： 10.1016/j.cell.2014.10.039

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  15 in total

Review 1.  Stem cells as vehicles for youthful regeneration of aged tissues.

Authors:  Thomas A Rando; Tony Wyss-Coray
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-06       Impact factor: 6.053

Review 2.  Aging and reprogramming: a two-way street.

Authors:  Salah Mahmoudi; Anne Brunet
Journal:  Curr Opin Cell Biol       Date:  2012-11-09       Impact factor: 8.382

3.  Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.

Authors:  Darren J Baker; Tobias Wijshake; Tamar Tchkonia; Nathan K LeBrasseur; Bennett G Childs; Bart van de Sluis; James L Kirkland; Jan M van Deursen
Journal:  Nature       Date:  2011-11-02       Impact factor: 49.962

Review 4.  Is HIV a model of accelerated or accentuated aging?

Authors:  Sophia Pathai; Hendren Bajillan; Alan L Landay; Kevin P High
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2013-10-24       Impact factor: 6.053

Review 5.  Drugs that modulate aging: the promising yet difficult path ahead.

Authors:  Brian K Kennedy; Juniper K Pennypacker
Journal:  Transl Res       Date:  2013-11-20       Impact factor: 7.012

Review 6.  You are what you host: microbiome modulation of the aging process.

Authors:  Caroline Heintz; William Mair
Journal:  Cell       Date:  2014-01-30       Impact factor: 41.582

Review 7.  The impact of CMV infection on survival in older humans.

Authors:  Graham Pawelec; Janet E McElhaney; Allison E Aiello; Evelyna Derhovanessian
Journal:  Curr Opin Immunol       Date:  2012-04-27       Impact factor: 7.486

Review 8.  mTOR is a key modulator of ageing and age-related disease.

Authors:  Simon C Johnson; Peter S Rabinovitch; Matt Kaeberlein
Journal:  Nature       Date:  2013-01-17       Impact factor: 49.962

Review 9.  Survivors of childhood and adolescent cancer: life-long risks and responsibilities.

Authors:  Leslie L Robison; Melissa M Hudson
Journal:  Nat Rev Cancer       Date:  2013-12-05       Impact factor: 60.716

10.  Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Authors:  Jean-Philippe Coppé; Christopher K Patil; Francis Rodier; Yu Sun; Denise P Muñoz; Joshua Goldstein; Peter S Nelson; Pierre-Yves Desprez; Judith Campisi
Journal:  PLoS Biol       Date:  2008-12-02       Impact factor: 8.029
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  629 in total

1.  Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society.

Authors:  Janko Nikolich-Žugich; Dana P Goldman; Paul R Cohen; Denis Cortese; Luigi Fontana; Brian K Kennedy; M Jane Mohler; S Jay Olshansky; Thomas Perls; Daniel Perry; Arlan Richardson; Christine Ritchie; Anne M Wertheimer; Richard G A Faragher; Mindy J Fain
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2015-09-29       Impact factor: 6.053

Review 2.  Lifespan and Healthspan: Past, Present, and Promise.

Authors:  Eileen M Crimmins
Journal:  Gerontologist       Date:  2015-11-10

3.  Is the onset of obesity the same as aging?

Authors:  Anne B Newman
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-16       Impact factor: 11.205

4.  DCAF1 regulates Treg senescence via the ROS axis during immunological aging.

Authors:  Zengli Guo; Gang Wang; Bing Wu; Wei-Chun Chou; Liang Cheng; Chenlin Zhou; Jitong Lou; Di Wu; Lishan Su; Junnian Zheng; Jenny P-Y Ting; Yisong Y Wan
Journal:  J Clin Invest       Date:  2020-11-02       Impact factor: 14.808

Review 5.  Mitochondrial pathways in human health and aging.

Authors:  Rebecca Bornstein; Brenda Gonzalez; Simon C Johnson
Journal:  Mitochondrion       Date:  2020-07-30       Impact factor: 4.160

Review 6.  The Essence of Aging.

Authors:  Jan Vijg; Brian K Kennedy
Journal:  Gerontology       Date:  2015-09-22       Impact factor: 5.140

Review 7.  Type 2 diabetes mellitus in older adults: clinical considerations and management.

Authors:  Srikanth Bellary; Ioannis Kyrou; James E Brown; Clifford J Bailey
Journal:  Nat Rev Endocrinol       Date:  2021-06-25       Impact factor: 43.330

8.  A toolkit for DNA assembly, genome engineering and multicolor imaging for C. elegans.

Authors:  Bryan Sands; Nikolay Burnaevskiy; Soo R Yun; Mathew M Crane; Matt Kaeberlein; Alexander Mendenhall
Journal:  Transl Med Aging       Date:  2018-04-13

9.  Identifying and Implementing Endpoints for Geriatric Mice.

Authors:  Linda A Toth
Journal:  Comp Med       Date:  2018-11-28       Impact factor: 0.982

Review 10.  The Spectrum of Fundamental Basic Science Discoveries Contributing to Organismal Aging.

Authors:  Joshua N Farr; Maria Almeida
Journal:  J Bone Miner Res       Date:  2018-08-13       Impact factor: 6.741
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