Literature DB >> 26419976

Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society.

Janko Nikolich-Žugich1, Dana P Goldman2, Paul R Cohen3, Denis Cortese4, Luigi Fontana5, Brian K Kennedy6, M Jane Mohler7, S Jay Olshansky8, Thomas Perls9, Daniel Perry10, Arlan Richardson11, Christine Ritchie12, Anne M Wertheimer7, Richard G A Faragher13, Mindy J Fain7.   

Abstract

Although the demographic revolution has produced hundreds of millions people aged 65 and older, a substantial segment of that population is not enjoying the benefits of extended healthspan. Many live with multiple chronic conditions and disabilities that erode the quality of life. The consequences are also costly for society. In the United States, the most costly 5% of Medicare beneficiaries account for approximately 50% of Medicare's expenditures. This perspective summarizes a recent workshop on biomedical approaches to best extend healthspan as way to reduce age-related dysfunction and disability. We further specify the action items necessary to unite health professionals, scientists, and the society to partner around the exciting and palpable opportunities to extend healthspan.
© The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Healthspan; Longevity dividend; Models of care

Mesh:

Year:  2015        PMID: 26419976      PMCID: PMC5014189          DOI: 10.1093/gerona/glv164

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  59 in total

1.  Between Scylla and Charybdis: p53 links tumor suppression and aging.

Authors:  Judith Campisi
Journal:  Mech Ageing Dev       Date:  2002-03-31       Impact factor: 5.432

Review 2.  Are sirtuins viable targets for improving healthspan and lifespan?

Authors:  Joseph A Baur; Zoltan Ungvari; Robin K Minor; David G Le Couteur; Rafael de Cabo
Journal:  Nat Rev Drug Discov       Date:  2012-06-01       Impact factor: 84.694

Review 3.  Pursuing the longevity dividend: scientific goals for an aging world.

Authors:  S Jay Olshansky; Daniel Perry; Richard A Miller; Robert N Butler
Journal:  Ann N Y Acad Sci       Date:  2007-10       Impact factor: 5.691

4.  Frailty in older adults: evidence for a phenotype.

Authors:  L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-03       Impact factor: 6.053

5.  Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging.

Authors:  Yun-Hee Youm; Ryan W Grant; Laura R McCabe; Diana C Albarado; Kim Yen Nguyen; Anthony Ravussin; Paul Pistell; Susan Newman; Renee Carter; Amanda Laque; Heike Münzberg; Clifford J Rosen; Donald K Ingram; J Michael Salbaum; Vishwa Deep Dixit
Journal:  Cell Metab       Date:  2013-10-01       Impact factor: 27.287

6.  Are the young becoming more disabled?

Authors:  Darius N Lakdawalla; Jayanta Bhattacharya; Dana P Goldman
Journal:  Health Aff (Millwood)       Date:  2004 Jan-Feb       Impact factor: 6.301

7.  Rapamycin extends murine lifespan but has limited effects on aging.

Authors:  Frauke Neff; Diana Flores-Dominguez; Devon P Ryan; Marion Horsch; Susanne Schröder; Thure Adler; Luciana Caminha Afonso; Juan Antonio Aguilar-Pimentel; Lore Becker; Lillian Garrett; Wolfgang Hans; Moritz M Hettich; Richard Holtmeier; Sabine M Hölter; Kristin Moreth; Cornelia Prehn; Oliver Puk; Ildikó Rácz; Birgit Rathkolb; Jan Rozman; Beatrix Naton; Rainer Ordemann; Jerzy Adamski; Johannes Beckers; Raffi Bekeredjian; Dirk H Busch; Gerhard Ehninger; Jochen Graw; Heinz Höfler; Martin Klingenspor; Thomas Klopstock; Markus Ollert; Jörg Stypmann; Eckhard Wolf; Wolfgang Wurst; Andreas Zimmer; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabe de Angelis; Dan Ehninger
Journal:  J Clin Invest       Date:  2013-07-25       Impact factor: 14.808

8.  Upregulated monocytic expression of CXC chemokine ligand 10 (CXCL-10) and its relationship with serum interleukin-6 levels in the syndrome of frailty.

Authors:  Tao Qu; Huanle Yang; Jeremy D Walston; Neal S Fedarko; Sean X Leng
Journal:  Cytokine       Date:  2009-04-01       Impact factor: 3.861

9.  Rapamycin slows aging in mice.

Authors:  John E Wilkinson; Lisa Burmeister; Susan V Brooks; Chi-Chao Chan; Sabrina Friedline; David E Harrison; James F Hejtmancik; Nancy Nadon; Randy Strong; Lauren K Wood; Maria A Woodward; Richard A Miller
Journal:  Aging Cell       Date:  2012-06-04       Impact factor: 9.304

Review 10.  Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.

Authors:  Claudio Franceschi; Judith Campisi
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-06       Impact factor: 6.053

View more
  15 in total

1.  How healthy is the healthspan concept?

Authors:  Matt Kaeberlein
Journal:  Geroscience       Date:  2018-08-06       Impact factor: 7.713

Review 2.  Recent Advances in the Systems Biology of Aging.

Authors:  Mark A McCormick; Daniel E L Promislow
Journal:  Antioxid Redox Signal       Date:  2017-11-20       Impact factor: 8.401

3.  The Effectiveness of a PRoactive Multicomponent Intervention Program on Disability in Independently Living Older People: A Randomized Controlled Trial.

Authors:  M R J van Lieshout; N Bleijenberg; M J Schuurmans; N J de Wit
Journal:  J Nutr Health Aging       Date:  2018       Impact factor: 4.075

4.  Heterogeneity of Human Aging and Its Assessment.

Authors:  Arnold Mitnitski; Susan E Howlett; Kenneth Rockwood
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2017-07-01       Impact factor: 6.053

5.  Metabolic View on Human Healthspan: A Lipidome-Wide Association Study.

Authors:  Justin Carrard; Hector Gallart-Ayala; Denis Infanger; Tony Teav; Jonathan Wagner; Raphael Knaier; Flora Colledge; Lukas Streese; Karsten Königstein; Timo Hinrichs; Henner Hanssen; Julijana Ivanisevic; Arno Schmidt-Trucksäss
Journal:  Metabolites       Date:  2021-04-30

6.  Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms.

Authors:  Christin E Burd; Matthew S Gill; Laura J Niedernhofer; Paul D Robbins; Steven N Austad; Nir Barzilai; James L Kirkland
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2016-08-16       Impact factor: 6.053

7.  Japanese Community Pharmacists' Dispensing Influences Medicine Price Reduction more than Prescription Numbers.

Authors:  Masayuki Yokoi; Takao Tashiro
Journal:  Glob J Health Sci       Date:  2016-09-01

8.  The rate of change in declining steroid hormones: a new parameter of healthy aging in men?

Authors:  Andreas Walther; Michel Philipp; Niclà Lozza; Ulrike Ehlert
Journal:  Oncotarget       Date:  2016-09-20

Review 9.  Self-Care for the Prevention and Management of Cardiovascular Disease and Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association.

Authors:  Barbara Riegel; Debra K Moser; Harleah G Buck; Victoria Vaughan Dickson; Sandra B Dunbar; Christopher S Lee; Terry A Lennie; JoAnn Lindenfeld; Judith E Mitchell; Diane J Treat-Jacobson; David E Webber
Journal:  J Am Heart Assoc       Date:  2017-08-31       Impact factor: 5.501

10.  Prevalence and the factors associated with malnutrition risk in elderly Chinese inpatients.

Authors:  Rong Liu; Wenchao Shao; Nianzhe Sun; Jonathan King-Lam Lai; Lingshan Zhou; Man Ren; Chendong Qiao
Journal:  Aging Med (Milton)       Date:  2021-02-17
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.