Literature DB >> 25407981

Synthesis of imidazo[1,2-a]pyridines: a decade update.

Avik Kumar Bagdi1, Sougata Santra, Kamarul Monir, Alakananda Hajra.   

Abstract

Imidazopyridine is one of the important fused bicyclic 5-6 heterocycles and it is recognized as a "drug prejudice" scaffold due to its wide range of applications in medicinal chemistry. This moiety is also useful in material science because of its structural character. Synthesis of this moiety from the easily available chemicals is desirable due to its tremendous use in the various branches of chemistry. Here we report a review on the synthesis of this scaffold employing different strategies such as condensation, multicomponent reactions, oxidative coupling, tandem reactions, aminooxygenation, and hydroamination reactions.

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Year:  2015        PMID: 25407981     DOI: 10.1039/c4cc08495k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  29 in total

Review 1.  Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage.

Authors:  Gagandeep Kour Reen; Ashok Kumar; Pratibha Sharma
Journal:  Beilstein J Org Chem       Date:  2019-07-19       Impact factor: 2.883

2.  Crystal structure and Hirshfeld surface analysis of 2,2,2-tri-fluoro-1-(7-methyl-imidazo[1,2-a]pyridin-3-yl)ethan-1-one.

Authors:  Firudin I Guseinov; Konstantin I Kobrakov; Bogdan I Ugrak; Zeliha Atioğlu; Mehmet Akkurt; Ajaya Bhattarai
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2022-01-01

3.  Copper-catalyzed three-component reaction to synthesize polysubstituted imidazo[1,2-a]pyridines.

Authors:  Zitong Zhou; Danyang Luo; Guanrong Li; Zhongtao Yang; Liao Cui; Weiguang Yang
Journal:  RSC Adv       Date:  2022-07-14       Impact factor: 4.036

4.  Ι₂-mediated amination/cyclization of ketones with 2-aminopyridines under high-speed ball milling: solvent- and metal-free synthesis of 2,3-substituted imidazo[1,2-a]pyridines and zolimidine.

Authors:  Fang-Jian Wang; Hui Xu; Ming Xin; Ze Zhang
Journal:  Mol Divers       Date:  2016-03-14       Impact factor: 2.943

5.  Selective, C-3 Friedel-Crafts acylation to generate functionally diverse, acetylated Imidazo[1,2-a]pyridine derivatives.

Authors:  Brendan Frett; Nicholas McConnell; Anupreet Kharbanda; Gunaganti Naresh; Benjamin Rounseville; Christina Warner; John Chang; Natalie Debolske; Hong-Yu Li
Journal:  Tetrahedron       Date:  2018-07-17       Impact factor: 2.457

6.  Annulation of Hydrazones and Alkynes via Rhodium(III)-Catalyzed Dual C-H Activation: Synthesis of Pyrrolopyridazines and Azolopyridazines.

Authors:  Andrew D Streit; Adam J Zoll; Gia L Hoang; Jonathan A Ellman
Journal:  Org Lett       Date:  2020-01-24       Impact factor: 6.005

7.  Design, synthesis and biological evaluation of imidazopyridine-propenone conjugates as potent tubulin inhibitors.

Authors:  Ibrahim Bin Sayeed; V Lakshma Nayak; Mohd Adil Shareef; Neeraj Kumar Chouhan; Ahmed Kamal
Journal:  Medchemcomm       Date:  2017-03-06       Impact factor: 3.597

8.  Transition-metal-free regioselective C-H halogenation of imidazo[1,2-a]pyridines: sodium chlorite/bromite as the halogen source.

Authors:  Junxuan Li; Jiayi Tang; Yuanheng Wu; Qiuxing He; Yue Yu
Journal:  RSC Adv       Date:  2018-02-01       Impact factor: 4.036

9.  Structural characterization and Hirshfeld surface analysis of a CoII complex with imidazo[1,2-a]pyridine.

Authors:  Saikat Kumar Seth
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2018-04-17

10.  Iodine Promoted Efficient Synthesis of 2-Arylimidazo[1,2-a]pyridines in Aqueous Media: A Comparative Study between Micellar Catalysis and an "On-Water" Platform.

Authors:  Zigmee T Bhutia; Padmini C Panjikar; Shruti Iyer; Amrita Chatterjee; Mainak Banerjee
Journal:  ACS Omega       Date:  2020-05-26
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