Literature DB >> 25402770

Secondary structure reshuffling modulates glycosyltransferase function at the membrane.

David Giganti1, David Albesa-Jové2, Saioa Urresti2, Ane Rodrigo-Unzueta2, Mariano A Martínez3, Natalia Comino2, Nathalie Barilone3, Marco Bellinzoni3, Alexandre Chenal4, Marcelo E Guerin5, Pedro M Alzari3.   

Abstract

Secondary structure refolding is a key event in biology as it modulates the conformation of many proteins in the cell, generating functional or aberrant states. The crystal structures of mannosyltransferase PimA reveal an exceptional flexibility of the protein along the catalytic cycle, including β-strand-to-α-helix and α-helix-to-β-strand transitions. These structural changes modulate catalysis and are promoted by interactions of the protein with anionic phospholipids in the membrane.

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Year:  2014        PMID： 25402770     DOI： 10.1038/nchembio.1694

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


  25 in total

1.  Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction.

Authors:  Caroline Montagner; Aurélie Perier; Sylvain Pichard; Grégory Vernier; André Ménez; Daniel Gillet; Vincent Forge; Alexandre Chenal
Journal:  Biochemistry       Date:  2007-01-24       Impact factor: 3.162

2.  Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.

Authors:  Marcelo E Guerin; Jana Kordulakova; Francis Schaeffer; Zuzana Svetlikova; Alejandro Buschiazzo; David Giganti; Brigitte Gicquel; Katarina Mikusova; Mary Jackson; Pedro M Alzari
Journal:  J Biol Chem       Date:  2007-05-16       Impact factor: 5.157

3.  Unfolding pathway of the colicin E1 channel protein on a membrane surface.

Authors:  M Lindeberg; S D Zakharov; W A Cramer
Journal:  J Mol Biol       Date:  2000-01-21       Impact factor: 5.469

4.  Rapid measurement of binding constants and heats of binding using a new titration calorimeter.

Authors:  T Wiseman; S Williston; J F Brandts; L N Lin
Journal:  Anal Biochem       Date:  1989-05-15       Impact factor: 3.365

5.  Large-scale purification of a stable form of recombinant tobacco etch virus protease.

Authors:  L J Lucast; R T Batey; J A Doudna
Journal:  Biotechniques       Date:  2001-03       Impact factor: 1.993

6.  Tryptophan residues promote membrane association for a plant lipid glycosyltransferase involved in phosphate stress.

Authors:  Changrong Ge; Alexander Georgiev; Anders Öhman; Åke Wieslander; Amélie A Kelly
Journal:  J Biol Chem       Date:  2010-12-14       Impact factor: 5.157

7.  Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases.

Authors:  Yanan Hu; Lan Chen; Sha Ha; Ben Gross; Brian Falcone; Deborah Walker; Maryam Mokhtarzadeh; Suzanne Walker
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-21       Impact factor: 11.205

8.  Using Situs for the integration of multi-resolution structures.

Authors:  Willy Wriggers
Journal:  Biophys Rev       Date:  2010-01-08

9.  Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria.

Authors:  Jana Korduláková; Martine Gilleron; Katarína Mikusova; Germain Puzo; Patrick J Brennan; Brigitte Gicquel; Mary Jackson
Journal:  J Biol Chem       Date:  2002-06-14       Impact factor: 5.157

10.  Phaser crystallographic software.

Authors:  Airlie J McCoy; Ralf W Grosse-Kunstleve; Paul D Adams; Martyn D Winn; Laurent C Storoni; Randy J Read
Journal:  J Appl Crystallogr       Date:  2007-07-13       Impact factor: 3.304
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  21 in total

Review 1.  Membrane enzymes: transformers at the interface.

Authors:  Florian Brodhun; Kai Tittmann
Journal:  Nat Chem Biol       Date:  2015-01-12       Impact factor: 15.040

2.  A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch.

Authors:  Jeanine F Amacher; Fangfang Zhong; George P Lisi; Michael Q Zhu; Stephanie L Alden; Kevin R Hoke; Dean R Madden; Ekaterina V Pletneva
Journal:  J Am Chem Soc       Date:  2015-06-24       Impact factor: 15.419

Review 3.  Learning from the past for TB drug discovery in the future.

Authors:  Katarína Mikušová; Sean Ekins
Journal:  Drug Discov Today       Date:  2016-10-04       Impact factor: 7.851

4.  AlphaFold2 fails to predict protein fold switching.

Authors:  Devlina Chakravarty; Lauren L Porter
Journal:  Protein Sci       Date:  2022-06       Impact factor: 6.993

5.  Molecular Basis of Membrane Association by the Phosphatidylinositol Mannosyltransferase PimA Enzyme from Mycobacteria.

Authors:  Ane Rodrigo-Unzueta; Mariano A Martínez; Natalia Comino; Pedro M Alzari; Alexandre Chenal; Marcelo E Guerin
Journal:  J Biol Chem       Date:  2016-05-09       Impact factor: 5.157

6.  The Phosphatidyl-myo-Inositol Dimannoside Acyltransferase PatA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo.

Authors:  Francesca Boldrin; Itxaso Anso; Sogol Alebouyeh; Iker A Sevilla; Mariví Geijo; Joseba M Garrido; Alberto Marina; Laura Cioetto Mazzabò; Greta Segafreddo; Marcelo E Guerin; Riccardo Manganelli; Rafael Prados-Rosales
Journal:  J Bacteriol       Date:  2021-03-08       Impact factor: 3.490

7.  Predictable fold switching by the SARS-CoV-2 protein ORF9b.

Authors:  Lauren L Porter
Journal:  Protein Sci       Date:  2021-05-10       Impact factor: 6.993

8.  Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.

Authors:  David Albesa-Jové; Zuzana Svetlíková; Montse Tersa; Enea Sancho-Vaello; Ana Carreras-González; Pascal Bonnet; Pedro Arrasate; Ander Eguskiza; Shiva K Angala; Javier O Cifuente; Jana Korduláková; Mary Jackson; Katarína Mikušová; Marcelo E Guerin
Journal:  Nat Commun       Date:  2016-03-11       Impact factor: 14.919

Review 9.  Functional and Regulatory Roles of Fold-Switching Proteins.

Authors:  Allen K Kim; Lauren L Porter
Journal:  Structure       Date:  2020-11-10       Impact factor: 5.006

10.  TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.

Authors:  Stéphanie Thébault; Morgane Agez; Xiaoke Chi; Johann Stojko; Vincent Cura; Stéphanie B Telerman; Laurent Maillet; Fabien Gautier; Isabelle Billas-Massobrio; Catherine Birck; Nathalie Troffer-Charlier; Teele Karafin; Joane Honoré; Andrea Senff-Ribeiro; Sylvie Montessuit; Christopher M Johnson; Philippe Juin; Sarah Cianférani; Jean-Claude Martinou; David W Andrews; Robert Amson; Adam Telerman; Jean Cavarelli
Journal:  Sci Rep       Date:  2016-01-27       Impact factor: 4.379
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