Literature DB >> 2538722

An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene.

S E Hyman1, M Comb, J Pearlberg, H M Goodman.   

Abstract

An enhancer with two DNA elements, one containing the sequence CGTCA, is required for cyclic AMP- and phorbol ester-inducible transcription of the human proenkephalin gene. We report that an AP-2 element located adjacent to the enhancer acts synergistically with it to confer maximal response to cyclic AMP and phorbol esters.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2538722      PMCID： PMC362175          DOI： 10.1128/mcb.9.1.321-324.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  18 in total

1.  Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.

Authors:  M Imagawa; R Chiu; M Karin
Journal:  Cell       Date:  1987-10-23       Impact factor: 41.582

2.  A common trans-acting factor is involved in transcriptional regulation of neurotransmitter genes by cyclic AMP.

Authors:  S E Hyman; M Comb; Y S Lin; J Pearlberg; M R Green; H M Goodman
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

3.  A simple phase-extraction assay for chloramphenicol acyltransferase activity.

Authors:  B Seed; J Y Sheen
Journal:  Gene       Date:  1988-07-30       Impact factor: 3.688

4.  Affinity purification of sequence-specific DNA binding proteins.

Authors:  J T Kadonaga; R Tjian
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

5.  Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements.

Authors:  T Edlund; M D Walker; P J Barr; W J Rutter
Journal:  Science       Date:  1985-11-22       Impact factor: 47.728

6.  Supercoil sequencing: a fast and simple method for sequencing plasmid DNA.

Authors:  E Y Chen; P H Seeburg
Journal:  DNA       Date:  1985-04

7.  Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

Authors:  J D Dignam; R M Lebovitz; R G Roeder
Journal:  Nucleic Acids Res       Date:  1983-03-11       Impact factor: 16.971

8.  Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor.

Authors:  R Schüle; M Muller; H Otsuka-Murakami; R Renkawitz
Journal:  Nature       Date:  1988-03-03       Impact factor: 49.962

9.  High efficiency DNA-mediated transformation of primate cells.

Authors:  C Gorman; R Padmanabhan; B H Howard
Journal:  Science       Date:  1983-08-05       Impact factor: 47.728

10.  Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

Authors:  M R Montminy; K A Sevarino; J A Wagner; G Mandel; R H Goodman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205
View more
  35 in total

1.  PhosphoCREB and CREM/ICER: positive and negative regulation of proenkephalin gene expression in the paraventricular nucleus of the hypothalamus.

Authors:  D Borsook; O Smirnova; O Behar; S Lewis; L A Kobierski
Journal:  J Mol Neurosci       Date:  1999-02       Impact factor: 3.444

2.  Highly repeated sites in the apolipoprotein(a) gene recognized by methylated DNA-binding protein, a sequence-specific DNA-binding protein.

Authors:  K C Ehrlich; M Ehrlich
Journal:  Mol Cell Biol       Date:  1990-09       Impact factor: 4.272

Review 3.  Neuropeptide gene expression and neural activity: assessing a working hypothesis in nucleus caudalis and dorsal horn neurons expressing preproenkephalin and preprodynorphin.

Authors:  G R Uhl; T Nishimori
Journal:  Cell Mol Neurobiol       Date:  1990-03       Impact factor: 5.046

Review 4.  Molecular mechanisms of cAMP-regulated gene expression.

Authors:  K M Walton; R P Rehfuss
Journal:  Mol Neurobiol       Date:  1990 Fall-Winter       Impact factor: 5.590

5.  On the role of AP2 in epithelial-specific gene expression.

Authors:  T Magnaldo; R G Vidal; M Ohtsuki; I M Freedberg; M Blumenberg
Journal:  Gene Expr       Date:  1993

6.  Macromolecular interaction on a cAMP responsive region in the urokinase-type plasminogen activator gene: a role of protein phosphorylation.

Authors:  D von der Ahe; D Pearson; Y Nagamine
Journal:  Nucleic Acids Res       Date:  1990-04-25       Impact factor: 16.971

7.  Nuclear factor EF-1A binds to the adenovirus E1A core enhancer element and to other transcriptional control regions.

Authors:  J T Bruder; P Hearing
Journal:  Mol Cell Biol       Date:  1989-11       Impact factor: 4.272

8.  Transcription factor AP-2 regulates human apolipoprotein E gene expression in astrocytoma cells.

Authors:  M A García; J Vázquez; C Giménez; F Valdivieso; F Zafra
Journal:  J Neurosci       Date:  1996-12-01       Impact factor: 6.167

9.  Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress.

Authors:  D Borsook; C Konradi; O Falkowski; M Comb; S E Hyman
Journal:  Mol Endocrinol       Date:  1994-02

10.  AP-2alpha regulates migration of GN-11 neurons via a specific genetic programme involving the Axl receptor tyrosine kinase.

Authors:  Francesca Orso; Richard Jäger; Raffaele Adolfo Calogero; Hubert Schorle; Piero Sismondi; Michele De Bortoli; Daniela Taverna
Journal:  BMC Biol       Date:  2009-05-22       Impact factor: 7.431
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.