Literature DB >> 2537793

Frequency and molecular types of deletional alpha-thalassemia in Egypt.

A Novelletto1, M Hafez, A Di Rienzo, L Felicetti, G Deidda, Z el Morsi, Y al-Tonbary, M el-Ziny, N Abd-el-Gelil, L Terrenato.   

Abstract

The frequency of deletional alpha-thalassemia in the Egyptian population was estimated at 0.08 by DNA analysis of a newborn random sample. No alpha 0 determinants were found. The most frequent alpha+ determinant was the -alpha 3.7 type I in association with the medium allele at inter-zeta HVR. The -alpha 4.2 and alpha alpha alpha anti 3.7 arrangements were found at very low frequencies.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2537793     DOI： 10.1007/bf00278990

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  18 in total

1.  Alpha-thalassemia in Saudi Arabia: deletion pattern.

Authors:  M A el-Hazmi
Journal:  Hum Genet       Date:  1987-06       Impact factor: 4.132

2.  The polyadenylation site mutation in the alpha-globin gene cluster.

Authors:  S L Thein; R B Wallace; L Pressley; J B Clegg; D J Weatherall; D R Higgs
Journal:  Blood       Date:  1988-02       Impact factor: 22.113

3.  Melanesians and Polynesians share a unique alpha-thalassemia mutation.

Authors:  A V Hill; D K Bowden; R J Trent; D R Higgs; S J Oppenheimer; S L Thein; K N Mickleson; D J Weatherall; J B Clegg
Journal:  Am J Hum Genet       Date:  1985-05       Impact factor: 11.025

4.  Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.

Authors:  D R Higgs; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

Review 5.  DNA polymorphism and molecular pathology of the human globin gene clusters.

Authors:  S E Antonarakis; H H Kazazian; S H Orkin
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 6.  Alpha-thalassemia.

Authors:  D R Higgs; D J Weatherall
Journal:  Curr Top Hematol       Date:  1983

7.  Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis.

Authors:  J S Wainscoat; D R Higgs; E Kanavakis; A Cao; D Georgiou; J B Clegg; D J Weatherall
Journal:  Am J Hum Genet       Date:  1983-11       Impact factor: 11.025

8.  Thalassaemia in the egyptian population.

Authors:  Z Habib; J A Böök
Journal:  Hereditas       Date:  1982       Impact factor: 3.271

9.  Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.

Authors:  S H Embury; J A Miller; A M Dozy; Y W Kan; V Chan; D Todd
Journal:  J Clin Invest       Date:  1980-12       Impact factor: 14.808

10.  An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype.

Authors:  P Moi; F E Cash; S A Liebhaber; A Cao; M Pirastu
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808
View more
  1 in total

1.  Molecular characterization of beta-thalassemia mutations in Egypt.

Authors:  A Novelletto; M Hafez; G Deidda; A Di Rienzo; L Felicetti; H el-Tahan; Z el Morsi; M el-Ziny; Y al-Tonbary; A Sittien
Journal:  Hum Genet       Date:  1990-08       Impact factor: 4.132
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.