Literature DB >> 25377084

Plant natural products: from traditional compounds to new emerging drugs in cancer therapy.

L Ouyang1, Y Luo, M Tian, S-Y Zhang, R Lu, J-H Wang, R Kasimu, X Li.   

Abstract

Natural products are chemical compounds or substances produced naturally by living organisms. With the development of modern technology, more and more plant extracts have been found to be useful to medical practice. Both micromolecules and macromolecules have been reported to have the ability to inhibit tumour progression, a novel weapon to fight cancer by targeting its 10 characteristic hallmarks. In this review, we focus on summarizing plant natural compounds and their derivatives with anti-tumour properties, into categories, according to their potential therapeutic strategies against different types of human cancer. Taken together, we present a well-grounded review of these properties, hoping to shed new light on discovery of novel anti-tumour therapeutic drugs from known plant natural sources.
© 2014 John Wiley & Sons Ltd.

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Year:  2014        PMID: 25377084      PMCID: PMC6496831          DOI: 10.1111/cpr.12143

Source DB:  PubMed          Journal:  Cell Prolif        ISSN: 0960-7722            Impact factor:   6.831


  79 in total

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2.  Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction.

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3.  Induction of apoptosis and inhibition of c-erbB-2 in MDA-MB-435 cells by genistein.

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Review 4.  Breast cancer statistics, 2011.

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Journal:  CA Cancer J Clin       Date:  2011-10-03       Impact factor: 508.702

5.  Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells.

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Journal:  Carcinogenesis       Date:  2005-02-10       Impact factor: 4.944

6.  Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells.

Authors:  M Emília Juan; Uwe Wenzel; Hannelore Daniel; Joana M Planas
Journal:  J Agric Food Chem       Date:  2008-06-04       Impact factor: 5.279

7.  Honokiol, a natural therapeutic candidate, induces apoptosis and inhibits angiogenesis of ovarian tumor cells.

Authors:  Zhengyu Li; Yi Liu; Xia Zhao; Xiaoling Pan; Rutie Yin; Canhua Huang; Lijuan Chen; Yuquan Wei
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2008-04-28       Impact factor: 2.435

8.  Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.

Authors:  Dae-Hee Lee; Miroslaw-Jerzy Szczepanski; Yong J Lee
Journal:  J Cell Biochem       Date:  2009-04-15       Impact factor: 4.429

9.  Inhibition of prostate cancer cell colony formation by the flavonoid quercetin correlates with modulation of specific regulatory genes.

Authors:  Hari Krishnan Nair; Kesava V K Rao; Ravikumar Aalinkeel; Supriya Mahajan; Ram Chawda; Stanley A Schwartz
Journal:  Clin Diagn Lab Immunol       Date:  2004-01

10.  The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway.

Authors:  Prashanthi Javvadi; Andrew T Segan; Stephen W Tuttle; Constantinos Koumenis
Journal:  Mol Pharmacol       Date:  2008-02-05       Impact factor: 4.436

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  36 in total

1.  In silico analysis and experimental validation of active compounds from fructus Schisandrae chinensis in protection from hepatic injury.

Authors:  S Y Wang; L L Fu; S Y Zhang; M Tian; L Zhang; Y X Zheng; J H Wang; J Huang; L Ouyang
Journal:  Cell Prolif       Date:  2014-12-17       Impact factor: 6.831

Review 2.  Review of natural product databases.

Authors:  Tao Xie; Sicheng Song; Sijia Li; Liang Ouyang; Lin Xia; Jian Huang
Journal:  Cell Prolif       Date:  2015-05-25       Impact factor: 6.831

3.  Ferutinin Induces Membrane Depolarization, Permeability Transition Pore Formation, and Respiration Uncoupling in Isolated Rat Liver Mitochondria by Stimulation of Ca2+-Permeability.

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Journal:  J Membr Biol       Date:  2018-03-28       Impact factor: 1.843

4.  N-(p-coumaroyl) serotonin inhibits glioblastoma cells growth through triggering S-phase arrest and apoptosis.

Authors:  Diamanto Lazari; George A Alexiou; Georgios S Markopoulos; Evrysthenis Vartholomatos; Entela Hodaj; Ieremias Chousidis; Ioannis Leonardos; Vasiliki Galani; Athanasios P Kyritsis
Journal:  J Neurooncol       Date:  2017-04-01       Impact factor: 4.130

5.  Tissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum.

Authors:  Xiaowei Wang; Hongyan Hu; Zhijun Wu; Haili Fan; Guowei Wang; Tuanyao Chai; Hong Wang
Journal:  BMC Genomics       Date:  2021-05-17       Impact factor: 3.969

6.  Characterization of Caerulomycin A as a dual-targeting anticancer agent.

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Journal:  Eur J Pharmacol       Date:  2022-03-23       Impact factor: 5.195

Review 7.  The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders.

Authors:  Magdalena Działo; Justyna Mierziak; Urszula Korzun; Marta Preisner; Jan Szopa; Anna Kulma
Journal:  Int J Mol Sci       Date:  2016-02-18       Impact factor: 5.923

8.  Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6.

Authors:  Marina Pisano; Antonio Palomba; Alessandro Tanca; Daniela Pagnozzi; Sergio Uzzau; Maria Filippa Addis; Maria Antonietta Dettori; Davide Fabbri; Giuseppe Palmieri; Carla Rozzo
Journal:  BMC Cancer       Date:  2016-05-18       Impact factor: 4.430

9.  In silico identification of anti-cancer compounds and plants from traditional Chinese medicine database.

Authors:  Shao-Xing Dai; Wen-Xing Li; Fei-Fei Han; Yi-Cheng Guo; Jun-Juan Zheng; Jia-Qian Liu; Qian Wang; Yue-Dong Gao; Gong-Hua Li; Jing-Fei Huang
Journal:  Sci Rep       Date:  2016-05-05       Impact factor: 4.379

10.  Role of natural compounds in preventing and treating breast cancer.

Authors:  Brianna Noel; Santosh Kumar Singh; James W Lillard; Rajesh Singh
Journal:  Front Biosci (Schol Ed)       Date:  2020-03-01
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