Literature DB >> 25376496

A click-and-release approach to CO prodrugs.

Danzhu Wang1, Emilie Viennois, Kaili Ji, Krishna Damera, Alexander Draganov, Yueqing Zheng, Chaofeng Dai, Didier Merlin, Binghe Wang.   

Abstract

Carbon monoxide belongs to the family of signaling molecules and has been shown to possess therapeutic effects. Similar to NO, safe delivery of CO is a key issue in developing CO-based therapeutics. Herein we report a "click and release" CO-prodrug approach, which allows the release of CO under physiological conditions without the need for light irradiation. The system releases CO in a triggered and controllable manner and possesses the potential of tunable release rates.

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Year:  2014        PMID： 25376496     DOI： 10.1039/c4cc07748b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  20 in total

Review 1.  Toward Carbon Monoxide-Based Therapeutics: Critical Drug Delivery and Developability Issues.

Authors:  Xingyue Ji; Krishna Damera; Yueqin Zheng; Bingchen Yu; Leo E Otterbein; Binghe Wang
Journal:  J Pharm Sci       Date:  2016-01-06       Impact factor: 3.534

2.  Sulfur dioxide prodrugs: triggered release of SO2via a click reaction.

Authors:  Wenyi Wang; Xingyue Ji; Zhenming Du; Binghe Wang
Journal:  Chem Commun (Camb)       Date:  2017-01-24       Impact factor: 6.222

3.  Click and Fluoresce: A Bioorthogonally Activated Smart Probe for Wash-Free Fluorescent Labeling of Biomolecules.

Authors:  Xingyue Ji; Kaili Ji; Vayou Chittavong; Robert E Aghoghovbia; Mengyuan Zhu; Binghe Wang
Journal:  J Org Chem       Date:  2017-01-23       Impact factor: 4.354

4.  Preparation of a Nile Red-Pd-based fluorescent CO probe and its imaging applications in vitro and in vivo.

Authors:  Keyin Liu; Xiuqi Kong; Yanyan Ma; Weiying Lin
Journal:  Nat Protoc       Date:  2018-04-19       Impact factor: 13.491

5.  Click Chemistry with Cyclopentadiene.

Authors:  Brian J Levandowski; Ronald T Raines
Journal:  Chem Rev       Date:  2021-03-02       Impact factor: 60.622

6.  Organic CO Prodrugs: Structure-CO-Release Rate Relationship Studies.

Authors:  Zhixiang Pan; Vayou Chittavong; Wei Li; Jun Zhang; Kaili Ji; Mengyuan Zhu; Xingyue Ji; Binghe Wang
Journal:  Chemistry       Date:  2017-07-04       Impact factor: 5.236

7.  Towards "CO in a pill": Pharmacokinetic studies of carbon monoxide prodrugs in mice.

Authors:  Minjia Wang; Xiaoxiao Yang; Zhixiang Pan; Yingzhe Wang; Ladie Kimberly De La Cruz; Binghe Wang; Chalet Tan
Journal:  J Control Release       Date:  2020-08-01       Impact factor: 9.776

8.  Nitro reduction-based fluorescent probes for carbon monoxide require reactivity involving a ruthenium carbonyl moiety.

Authors:  Zhengnan Yuan; Xiaoxiao Yang; Ladie Kimberly De La Cruz; Binghe Wang
Journal:  Chem Commun (Camb)       Date:  2020-02-18       Impact factor: 6.222

Review 9.  Heme Oxygenase-1 and Carbon Monoxide in the Heart: The Balancing Act Between Danger Signaling and Pro-Survival.

Authors:  Leo E Otterbein; Roberta Foresti; Roberto Motterlini
Journal:  Circ Res       Date:  2016-06-10       Impact factor: 17.367

Review 10.  Carbon monoxide: An emerging therapy for acute kidney injury.

Authors:  Xiaoxiao Yang; Mark de Caestecker; Leo E Otterbein; Binghe Wang
Journal:  Med Res Rev       Date:  2019-12-09       Impact factor: 12.944
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