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Literature DB >> 28070577

Sulfur dioxide prodrugs: triggered release of SO₂via a click reaction.

Wenyi Wang¹, Xingyue Ji¹, Zhenming Du¹, Binghe Wang¹.

Abstract

Sulfur dioxide (SO2) is being recognized as a possible endogenous gasotransmitter with importance on par with that of NO, CO, and H2S. Herein we describe a series of SO2 prodrugs that are activated for SO2 release via a bioorthogonal click reaction. The release rate can be tuned by adjusting the substituents on the prodrug.

Entities: Chemical Disease Gene Species

Year: 2017 PMID： 28070577 PMCID： PMC5292044 DOI： 10.1039/c6cc08844a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

26 in total

1. Combined effect of cigarette smoking and sulfur dioxide on heart rate variability.

Authors: Jin-Young Min; Kyoung-Bok Min; Sung-Il Cho; Domyung Paek
Journal: Int J Cardiol Date: 2008-01-14 Impact factor: 4.164

Review 2. Significance of endogenous sulphur-containing gases in the cardiovascular system.

Authors: Xin-Bao Wang; Hong-Fang Jin; Chao-Shu Tang; Jun-Bao Du
Journal: Clin Exp Pharmacol Physiol Date: 2009-06-29 Impact factor: 2.557

3. Flow injection determination of gaseous sulfur dioxide with gas permeation denuder-based online sampling and preconcentration.

Authors: Zhong-Xian Guo; Yuan-Zong Li; Xin-Xiang Zhang; Wen-Bao Chang; Yun-Xiang Ci
Journal: Anal Bioanal Chem Date: 2002-10-24 Impact factor: 4.142

4. The vasodilator mechanism of sulfur dioxide on isolated aortic rings of rats: Involvement of the K+ and Ca2+ channels.

Authors: Quanxi Zhang; Ziqiang Meng
Journal: Eur J Pharmacol Date: 2008-11-25 Impact factor: 4.432

5. Vasodilatation of sulfur dioxide derivatives and signal transduction.

Authors: Ziqiang Meng; Yi Li; Junling Li
Journal: Arch Biochem Biophys Date: 2007-09-07 Impact factor: 4.013

Review 6. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine.

Authors: Martha H Stipanuk
Journal: Annu Rev Nutr Date: 2004 Impact factor: 11.848

7. Benzothiazole Sulfinate: a Water-Soluble and Slow-Releasing Sulfur Dioxide Donor.

Authors: Jacob J Day; Zhenhua Yang; Wei Chen; Armando Pacheco; Ming Xian
Journal: ACS Chem Biol Date: 2016-04-07 Impact factor: 5.100

8. Formation of sulfate from L-cysteine in rat liver mitochondria.

Authors: T Ubuka; S Yuasa; J Ohta; N Masuoka; K Yao; M Kinuta
Journal: Acta Med Okayama Date: 1990-04 Impact factor: 0.892

9. Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide.

Authors: Yueqin Zheng; Bingchen Yu; Kaili Ji; Zhixiang Pan; Vayou Chittavong; Binghe Wang
Journal: Angew Chem Int Ed Engl Date: 2016-01-28 Impact factor: 15.336

Review 10. Hydrogen sulfide prodrugs-a review.

Authors: Yueqin Zheng; Xingyue Ji; Kaili Ji; Binghe Wang
Journal: Acta Pharm Sin B Date: 2015-08-21 Impact factor: 11.413

9 in total

1. Click Chemistry with Cyclopentadiene.

Authors: Brian J Levandowski; Ronald T Raines
Journal: Chem Rev Date: 2021-03-02 Impact factor: 60.622

2. Organic CO Prodrugs: Structure-CO-Release Rate Relationship Studies.

Authors: Zhixiang Pan; Vayou Chittavong; Wei Li; Jun Zhang; Kaili Ji; Mengyuan Zhu; Xingyue Ji; Binghe Wang
Journal: Chemistry Date: 2017-07-04 Impact factor: 5.236

Review 3. Small molecule generators of biologically reactive sulfur species.

Authors: Prerona Bora; Preeti Chauhan; Kundansingh A Pardeshi; Harinath Chakrapani
Journal: RSC Adv Date: 2018-07-31 Impact factor: 4.036

4. Polymeric persulfide prodrugs: Mitigating oxidative stress through controlled delivery of reactive sulfur species.

Authors: Kearsley M Dillon; Ryan J Carrazzone; Yin Wang; Chadwick R Powell; John B Matson
Journal: ACS Macro Lett Date: 2020-04-07 Impact factor: 6.903

5. A Persulfide Donor Responsive to Reactive Oxygen Species: Insights into Reactivity and Therapeutic Potential.

Authors: Chadwick R Powell; Kearsley M Dillon; Yin Wang; Ryan J Carrazzone; John B Matson
Journal: Angew Chem Int Ed Engl Date: 2018-04-26 Impact factor: 15.336

6. Targeted Delivery of Persulfides to the Gut: Effects on the Microbiome.

Authors: Kearsley M Dillon; Holly A Morrison; Chadwick R Powell; Ryan J Carrazzone; Veronica M Ringel-Scaia; Ethan W Winckler; R McAlister Council-Troche; Irving C Allen; John B Matson
Journal: Angew Chem Int Ed Engl Date: 2021-01-29 Impact factor: 15.336

Sulfur dioxide prodrugs: triggered release of SO₂via a click reaction.

1. Combined effect of cigarette smoking and sulfur dioxide on heart rate variability.

Review 2. Significance of endogenous sulphur-containing gases in the cardiovascular system.

3. Flow injection determination of gaseous sulfur dioxide with gas permeation denuder-based online sampling and preconcentration.

4. The vasodilator mechanism of sulfur dioxide on isolated aortic rings of rats: Involvement of the K+ and Ca2+ channels.

5. Vasodilatation of sulfur dioxide derivatives and signal transduction.

Review 6. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine.

7. Benzothiazole Sulfinate: a Water-Soluble and Slow-Releasing Sulfur Dioxide Donor.

8. Formation of sulfate from L-cysteine in rat liver mitochondria.

9. Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide.

Review 10. Hydrogen sulfide prodrugs-a review.

1. Click Chemistry with Cyclopentadiene.

2. Organic CO Prodrugs: Structure-CO-Release Rate Relationship Studies.

Review 3. Small molecule generators of biologically reactive sulfur species.

4. Polymeric persulfide prodrugs: Mitigating oxidative stress through controlled delivery of reactive sulfur species.

5. A Persulfide Donor Responsive to Reactive Oxygen Species: Insights into Reactivity and Therapeutic Potential.

6. Targeted Delivery of Persulfides to the Gut: Effects on the Microbiome.

Review 7. Effect of sulfur dioxide on vascular biology.

Review 8. SO₂ Donors and Prodrugs, and Their Possible Applications: A Review.

Review 9. Nature's marvels endowed in gaseous molecules I: Carbon monoxide and its physiological and therapeutic roles.

Review 2. Significance of endogenous sulphur-containing gases in the cardiovascular system.

Review 6. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine.

Review 10. Hydrogen sulfide prodrugs-a review.

Review 3. Small molecule generators of biologically reactive sulfur species.

Review 7. Effect of sulfur dioxide on vascular biology.

Review 8. SO2 Donors and Prodrugs, and Their Possible Applications: A Review.

Review 9. Nature's marvels endowed in gaseous molecules I: Carbon monoxide and its physiological and therapeutic roles.

Review 8. SO₂ Donors and Prodrugs, and Their Possible Applications: A Review.