Literature DB >> 28544290

Organic CO Prodrugs: Structure-CO-Release Rate Relationship Studies.

Zhixiang Pan1, Vayou Chittavong1, Wei Li1,2, Jun Zhang1,3, Kaili Ji1, Mengyuan Zhu1, Xingyue Ji1, Binghe Wang1.   

Abstract

Carbon monoxide (CO) is an endogenously produced gasotransmitter in mammals, and may have signaling roles in bacteria as well. It has many recognized therapeutic effects. A significant challenge in this field is the development of pharmaceutically acceptable forms of CO delivery with controllable and tunable release rates. Herein, the structure-release rate studies of the first class of organic CO prodrugs that release CO in aqueous solution at neutral pH is described.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  carbon monoxide; click and release; metal free; prodrugs; release rate

Mesh：

Substances：

Year:  2017        PMID： 28544290      PMCID： PMC5679012          DOI： 10.1002/chem.201700936

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  44 in total

1.  The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin.

Authors:  R Tenhunen; H S Marver; R Schmid
Journal:  J Lab Clin Med       Date:  1970-03

2.  Fluorescein analogue xanthene-9-carboxylic acid: a transition-metal-free CO releasing molecule activated by green light.

Authors:  Lovely Angel Panamparambil Antony; Tomáš Slanina; Peter Šebej; Tomáš Šolomek; Petr Klán
Journal:  Org Lett       Date:  2013-08-19       Impact factor: 6.005

3.  CO releasing properties and cytoprotective effect of cis-trans-[Re(II)(CO)2Br2L2]n complexes.

Authors:  Fabio Zobi; Alois Degonda; Marcus C Schaub; Anna Yu Bogdanova
Journal:  Inorg Chem       Date:  2010-08-16       Impact factor: 5.165

4.  Design of biomaterials for intracellular delivery of carbon monoxide.

Authors:  Hiroshi Inaba; Kenta Fujita; Takafumi Ueno
Journal:  Biomater Sci       Date:  2015-11       Impact factor: 6.843

5.  A Photoactive Carbon-Monoxide-Releasing Protein Cage for Dose-Regulated Delivery in Living Cells.

Authors:  Kenta Fujita; Yuya Tanaka; Satoshi Abe; Takafumi Ueno
Journal:  Angew Chem Int Ed Engl       Date:  2015-09-02       Impact factor: 15.336

6.  Design strategies to improve the sensitivity of photoactive metal carbonyl complexes (photoCORMs) to visible light and their potential as CO-donors to biological targets.

Authors:  Indranil Chakraborty; Samantha J Carrington; Pradip K Mascharak
Journal:  Acc Chem Res       Date:  2014-07-08       Impact factor: 22.384

7.  Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide.

Authors:  Yueqin Zheng; Bingchen Yu; Kaili Ji; Zhixiang Pan; Vayou Chittavong; Binghe Wang
Journal:  Angew Chem Int Ed Engl       Date:  2016-01-28       Impact factor: 15.336

8.  Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth.

Authors:  Barbara Wegiel; David Gallo; Eva Csizmadia; Clair Harris; John Belcher; Gregory M Vercellotti; Nuno Penacho; Pankaj Seth; Vikas Sukhatme; Asif Ahmed; Pier Paolo Pandolfi; Leszek Helczynski; Anders Bjartell; Jenny Liao Persson; Leo E Otterbein
Journal:  Cancer Res       Date:  2013-10-11       Impact factor: 12.701

Review 9.  CO-releasing Metal Carbonyl Compounds as Antimicrobial Agents in the Post-antibiotic Era.

Authors:  Lauren K Wareham; Robert K Poole; Mariana Tinajero-Trejo
Journal:  J Biol Chem       Date:  2015-06-08       Impact factor: 5.157

10.  Self-Immolative Thiocarbamates Provide Access to Triggered H2S Donors and Analyte Replacement Fluorescent Probes.

Authors:  Andrea K Steiger; Sibile Pardue; Christopher G Kevil; Michael D Pluth
Journal:  J Am Chem Soc       Date:  2016-06-03       Impact factor: 15.419
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  13 in total

1.  Tracking CO release in cells via the luminescence of donor molecules and/or their by-products.

Authors:  Tatiana Soboleva; Lisa M Berreau
Journal:  Isr J Chem       Date:  2019-02-11       Impact factor: 3.333

Review 2.  Carbon Monoxide Signaling: Examining Its Engagement with Various Molecular Targets in the Context of Binding Affinity, Concentration, and Biologic Response.

Authors:  Zhengnan Yuan; Ladie Kimberly De La Cruz; Xiaoxiao Yang; Binghe Wang
Journal:  Pharmacol Rev       Date:  2022-07       Impact factor: 18.923

Review 3.  "CO in a pill": Towards oral delivery of carbon monoxide for therapeutic applications.

Authors:  Xiaoxiao Yang; Wen Lu; Minjia Wang; Chalet Tan; Binghe Wang
Journal:  J Control Release       Date:  2021-09-02       Impact factor: 11.467

4.  Flavonol-Based Carbon Monoxide Delivery Molecule with Endoplasmic Reticulum, Mitochondria, And Lysosome Localization.

Authors:  Livia S Lazarus; C Taylor Dederich; Stephen N Anderson; Abby D Benninghoff; Lisa M Berreau
Journal:  ACS Med Chem Lett       Date:  2022-02-01       Impact factor: 4.632

5.  Towards "CO in a pill": Pharmacokinetic studies of carbon monoxide prodrugs in mice.

Authors:  Minjia Wang; Xiaoxiao Yang; Zhixiang Pan; Yingzhe Wang; Ladie Kimberly De La Cruz; Binghe Wang; Chalet Tan
Journal:  J Control Release       Date:  2020-08-01       Impact factor: 9.776

Review 6.  Carbon monoxide: An emerging therapy for acute kidney injury.

Authors:  Xiaoxiao Yang; Mark de Caestecker; Leo E Otterbein; Binghe Wang
Journal:  Med Res Rev       Date:  2019-12-09       Impact factor: 12.944

Review 7.  Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance.

Authors:  Erik M Larsen; R Jeremy Johnson
Journal:  Drug Dev Res       Date:  2018-10-10       Impact factor: 4.360

8.  Chemical Reactivities of Two Widely Used Ruthenium-Based CO-Releasing Molecules with a Range of Biologically Important Reagents and Molecules.

Authors:  Zhengnan Yuan; Xiaoxiao Yang; Yuqian Ye; Ravi Tripathi; Binghe Wang
Journal:  Anal Chem       Date:  2021-03-21       Impact factor: 6.986

Review 9.  Nature's marvels endowed in gaseous molecules I: Carbon monoxide and its physiological and therapeutic roles.

Authors:  Xiaoxiao Yang; Wen Lu; Christopher P Hopper; Bowen Ke; Binghe Wang
Journal:  Acta Pharm Sin B       Date:  2020-10-16       Impact factor: 11.413

10.  Light-responsive paper strips as CO-releasing material with a colourimetric response.

Authors:  Upendar Reddy G; Jingjing Liu; Patrick Hoffmann; Johannes Steinmetzer; Helmar Görls; Stephan Kupfer; Sven H C Askes; Ute Neugebauer; Stefanie Gräfe; Alexander Schiller
Journal:  Chem Sci       Date:  2017-07-26       Impact factor: 9.825
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