Literature DB >> 25368901

A crystal structure of an oligoproline PPII-helix, at last.

Patrick Wilhelm1, Bartosz Lewandowski, Nils Trapp, Helma Wennemers.   

Abstract

The first crystal structure of an oligoproline adopting an all-trans polyproline II (PPII) helix is presented. The high-resolution structure provides detailed insight into the dimensions and conformational properties of oligoprolines that are important for, e.g., their use as "molecular rulers" and "molecular scaffolds". The structure also showed that the amides interact with each other within a PPII helix and that water is not necessary for PPII helicity.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25368901     DOI： 10.1021/ja507405j

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  25 in total

1.  De Novo Left-Handed Synthetic Peptidomimetic Foldamers.

Authors:  Fengyu She; Peng Teng; Alfredo Peguero-Tejada; Minghui Wang; Ning Ma; Timothy Odom; Mi Zhou; Erald Gjonaj; Lukasz Wojtas; Arjan van der Vaart; Jianfeng Cai
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-03       Impact factor: 15.336

2.  Theoretical Study of Shallow Distance Dependence of Proton-Coupled Electron Transfer in Oligoproline Peptides.

Authors:  Pengfei Li; Alexander V Soudackov; Brian Koronkiewicz; James M Mayer; Sharon Hammes-Schiffer
Journal:  J Am Chem Soc       Date:  2020-08-03       Impact factor: 15.419

3.  n→π* Interactions Are Competitive with Hydrogen Bonds.

Authors:  Robert W Newberry; Samuel J Orke; Ronald T Raines
Journal:  Org Lett       Date:  2016-07-13       Impact factor: 6.005

4.  Right-Handed Helical Foldamers Consisting of De Novo d-AApeptides.

Authors:  Peng Teng; Ning Ma; Darrell Cole Cerrato; Fengyu She; Timothy Odom; Xiang Wang; Li-June Ming; Arjan van der Vaart; Lukasz Wojtas; Hai Xu; Jianfeng Cai
Journal:  J Am Chem Soc       Date:  2017-05-16       Impact factor: 15.419

5.  n→π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines.

Authors:  Henry R Kilgore; Chase R Olsson; Kyan A D'Angelo; Mohammad Movassaghi; Ronald T Raines
Journal:  J Am Chem Soc       Date:  2020-08-21       Impact factor: 15.419

6.  4-Fluoroprolines: Conformational Analysis and Effects on the Stability and Folding of Peptides and Proteins.

Authors:  Robert W Newberry; Ronald T Raines
Journal:  Top Heterocycl Chem       Date:  2016-01-12

7.  Electronic and Steric Control of n→π* Interactions: Stabilization of the α-Helix Conformation without a Hydrogen Bond.

Authors:  Nicole A Wenzell; Himal K Ganguly; Anil K Pandey; Megh R Bhatt; Glenn P A Yap; Neal J Zondlo
Journal:  Chembiochem       Date:  2019-03-07       Impact factor: 3.164

8.  Replacing a single atom accelerates the folding of a protein and increases its thermostability.

Authors:  Ulrich Arnold; Ronald T Raines
Journal:  Org Biomol Chem       Date:  2016-07-12       Impact factor: 3.876

9.  Shallow Distance Dependence for Proton-Coupled Tyrosine Oxidation in Oligoproline Peptides.

Authors:  Brian Koronkiewicz; John Swierk; Kevin Regan; James M Mayer
Journal:  J Am Chem Soc       Date:  2020-06-29       Impact factor: 15.419

10.  Increasing protein stability by engineering the n → π* interaction at the β-turn.

Authors:  Bhavesh Khatri; Puja Majumder; Jayashree Nagesh; Aravind Penmatsa; Jayanta Chatterjee
Journal:  Chem Sci       Date:  2020-07-30       Impact factor: 9.825
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.