Literature DB >> 2536846

A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5' extension of int-2.

G Peters1, S Brookes, M Placzek, M Schuermann, R Michalides, C Dickson.   

Abstract

We extended the physical map of the mouse int-2 locus by demonstrating that the site of insertion for mouse mammary tumor virus DNA in plaque-type mammary tumors of GR mice is directly linked to int-2. An additional example of proviral integration is described in which a provirus in a presumed enhancer-insertion mode 15 kilobases upstream of the int-2 promoters is capable of activating expression of the gene at levels typical of other virally induced mammary tumors.

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Year:  1989        PMID： 2536846      PMCID： PMC247849     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

Review 1.  The activation of cellular oncogenes by proviral insertion in murine mammary cancer.

Authors:  R Nusse
Journal:  Cancer Treat Res       Date:  1988

2.  A rare common integration site of proviruses of the mouse mammary tumor virus in P-type mammary tumors of mouse strain GR.

Authors:  M Schuermann; R Michalides
Journal:  Virology       Date:  1987-02       Impact factor: 3.616

3.  A common mouse mammary tumor virus integration site in chemically induced precancerous mammary hyperplasias.

Authors:  D A Gray; C M McGrath; R F Jones; V L Morris
Journal:  Virology       Date:  1986-01-30       Impact factor: 3.616

4.  Concerted activation of two potential proto-oncogenes in carcinomas induced by mouse mammary tumour virus.

Authors:  G Peters; A E Lee; C Dickson
Journal:  Nature       Date:  1986 Apr 17-23       Impact factor: 49.962

5.  Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes.

Authors:  G Peters; C Kozak; C Dickson
Journal:  Mol Cell Biol       Date:  1984-02       Impact factor: 4.272

6.  Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2.

Authors:  C Dickson; R Smith; S Brookes; G Peters
Journal:  Cell       Date:  1984-06       Impact factor: 41.582

7.  Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15.

Authors:  R Nusse; A van Ooyen; D Cox; Y K Fung; H Varmus
Journal:  Nature       Date:  1984 Jan 12-18       Impact factor: 49.962

8.  A new site of integration for mouse mammary tumor virus proviral DNA common to BALB/cf(C3H) mammary and kidney adenocarcinomas.

Authors:  M Garcia; R Wellinger; A Vessaz; H Diggelmann
Journal:  EMBO J       Date:  1986-01       Impact factor: 11.598

9.  Multiple RNAs expressed from the int-2 gene in mouse embryonal carcinoma cell lines encode a protein with homology to fibroblast growth factors.

Authors:  R Smith; G Peters; C Dickson
Journal:  EMBO J       Date:  1988-04       Impact factor: 11.598

10.  Four classes of mRNA are expressed from the mouse int-2 gene, a member of the FGF gene family.

Authors:  S L Mansour; G R Martin
Journal:  EMBO J       Date:  1988-07       Impact factor: 11.598
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  5 in total

1.  Proviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact.

Authors:  C Dickson; R Smith; S Brookes; G Peters
Journal:  J Virol       Date:  1990-02       Impact factor: 5.103

2.  Evi-2, a common integration site involved in murine myeloid leukemogenesis.

Authors:  A M Buchberg; H G Bedigian; N A Jenkins; N G Copeland
Journal:  Mol Cell Biol       Date:  1990-09       Impact factor: 4.272

3.  The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.

Authors:  G Peters; S Brookes; R Smith; M Placzek; C Dickson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

4.  Expression of the int-1 and int-2 loci in endogenous mouse mammary tumor virus-induced mammary tumorigenesis in the C3Hf mouse.

Authors:  P R Etkind
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

5.  The mouse homologue of hst/k-FGF: sequence, genome organization and location relative to int-2.

Authors:  S Brookes; R Smith; J Thurlow; C Dickson; G Peters
Journal:  Nucleic Acids Res       Date:  1989-06-12       Impact factor: 16.971
  5 in total

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