| Literature DB >> 25341574 |
Jonathan A Ledermann1, Daniela Luvero, Aaron Shafer, Dennis O'Connor, Giorgia Mangili, Michael Friedlander, Jacobus Pfisterer, Mansoor R Mirza, Jae-Weon Kim, Jerome Alexandre, Amit Oza, Jubilee Brown.
Abstract
Mucinous carcinomas of the ovary can be primary or metastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary and metastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.Entities:
Mesh:
Year: 2014 PMID: 25341574 DOI: 10.1097/IGC.0000000000000296
Source DB: PubMed Journal: Int J Gynecol Cancer ISSN: 1048-891X Impact factor: 3.437