Literature DB >> 34912610

A Rare Presentation of Dual Ovarian Pathologies: Small Cell Carcinoma of the Ovary and Mucinous Ovarian Cancer.

Syed A Mannan1, Musa Azhar1, Jhanzeb Iftikhar1, Saad Khalil Chaudhry2, Maryam Hameed3.   

Abstract

The small cell carcinoma of ovaries co-occurring with mucinous ovarian cancer is a rare event. We report a 21-years-old lady with a composite tumour comprising small cell carcinoma and mucinous carcinoma of ovaries. The incidental finding of the left ovarian cyst led to further workup and revealed a solid cystic mass in the left adnexal area pathologically proven to be mucinous ovarian carcinoma. The initial surgery was deferred upon the patient's request. After a few more cycles of chemotherapy, at the completion of surgery as per ovarian protocol, the pathological evaluation showed small cell carcinoma in the left ovary with a residual focus of mucinous carcinoma. In contrast, the right ovary also showed surface deposits of small cell carcinoma. The patient's clinical condition deteriorated very rapidly after that, and she passed away. Early recognition of small cell carcinoma in a composite tumour is critically essential for timely intervention.
Copyright © 2021, Mannan et al.

Entities:  

Keywords:  dual primaries; gyne-oncology; mucinous ovarian cancer; ovarian cancer; small cell ovarian cancer

Year:  2021        PMID: 34912610      PMCID: PMC8665671          DOI: 10.7759/cureus.19468

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  11 in total

1.  Small cell of the ovary, hypercalcemic type -- analysis of combined experience and recommendation for management. A GCIG study.

Authors:  M L Harrison; P Hoskins; A du Bois; M Quinn; G J S Rustin; J A Ledermann; S Baron-Hay; M L Friedlander
Journal:  Gynecol Oncol       Date:  2006-02       Impact factor: 5.482

2.  Small cell carcinoma of the ovary of hypercalcemic type: a case report.

Authors:  J Matt McDonald; Rouzan G Karabakhtsian; Heather H Pierce; Joseph A Iocono; Christopher P Desimone; Sherry L Bayliff; Frederick R Ueland
Journal:  J Pediatr Surg       Date:  2012-03       Impact factor: 2.545

3.  [Small cell carcinoma of the ovary].

Authors:  M Bahri; R Lahmar; H Ben Salah; N Kallel; M Ben Amar; J Daoud
Journal:  Cancer Radiother       Date:  2014-03-14       Impact factor: 1.018

Review 4.  Gynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma.

Authors:  Jonathan A Ledermann; Daniela Luvero; Aaron Shafer; Dennis O'Connor; Giorgia Mangili; Michael Friedlander; Jacobus Pfisterer; Mansoor R Mirza; Jae-Weon Kim; Jerome Alexandre; Amit Oza; Jubilee Brown
Journal:  Int J Gynecol Cancer       Date:  2014-11       Impact factor: 3.437

5.  Small cell carcinoma of the ovary-hypercalcemic type (SCCOHT): A review of 47 cases.

Authors:  D Callegaro-Filho; D M Gershenson; A M Nick; M F Munsell; P T Ramirez; P J Eifel; E D Euscher; R M Marques; S M Nicolau; K M Schmeler
Journal:  Gynecol Oncol       Date:  2015-11-04       Impact factor: 5.482

6.  Small Cell Carcinoma of the Ovary: Clinicopathologic and Immunohistochemical Analysis of 7 New Cases of a Rare Malignancy.

Authors:  Parikshaa Gupta; Gargi Kapatia; Nalini Gupta; Pranab Dey; Manish Rohilla; Ankita Gupta; Bhavana Rai; Vanita Suri; Arvind Rajwanshi; Radhika Srinivasan
Journal:  Int J Surg Pathol       Date:  2020-08-10       Impact factor: 1.271

7.  Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

Authors:  Anthony N Karnezis; Yemin Wang; Pilar Ramos; William Pd Hendricks; Esther Oliva; Emanuela D'Angelo; Jaime Prat; Marisa R Nucci; Torsten O Nielsen; Christine Chow; Samuel Leung; Friedrich Kommoss; Stefan Kommoss; Annacarolina Silva; Brigitte M Ronnett; Joseph T Rabban; David D Bowtell; Bernard E Weissman; Jeffrey M Trent; C Blake Gilks; David G Huntsman
Journal:  J Pathol       Date:  2015-12-21       Impact factor: 7.996

8.  Primary small cell ovarian cancer of pulmonary type: A case report.

Authors:  Emmanouil Kalampokas; Vijay Sharma; Tanja Gagliardi; Fiona Payne; Mahalakshmi Gurumurthy
Journal:  Gynecol Oncol Rep       Date:  2018-02-08

Review 9.  An In-Depth Look at Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT): Clinical Implications from Recent Molecular Findings.

Authors:  Bingjian Lu; Haiyan Shi
Journal:  J Cancer       Date:  2019-01-01       Impact factor: 4.207

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  1 in total

1.  Case report: Strategies for improving outcomes in patients with primary ovarian small-cell neuroendocrine carcinoma.

Authors:  YingYing Li; Yueling Wu; Ying Zhang; Xiaofang Li
Journal:  Front Oncol       Date:  2022-09-23       Impact factor: 5.738

  1 in total

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