BACKGROUND: The role of glucan in the stimulation of immune reactions is well established. In our report, we focused on the effects of orally administered glucan on nonspecific immunity of children with chronic respiratory problems. MATERIALS AND METHODS: We measured the levels of albumin, lysozyme. C-reactive protein (CRP) and calprotectin in the saliva of 60 children ages 8-12 years and evaluated the effects of 30-day treatment with 100 mg/d oral dose of glucan. RESULTS: We found a significant increase in the production of lysozyme, CRP and calprotectin in glucan-treated children. CONCLUSIONS: Short-term oral application of natural immunomodulator β-glucan significantly stimulated mucosal immunity of children with chronic respiratory problems.
BACKGROUND: The role of glucan in the stimulation of immune reactions is well established. In our report, we focused on the effects of orally administered glucan on nonspecific immunity of children with chronic respiratory problems. MATERIALS AND METHODS: We measured the levels of albumin, lysozyme. C-reactive protein (CRP) and calprotectin in the saliva of 60 children ages 8-12 years and evaluated the effects of 30-day treatment with 100 mg/d oral dose of glucan. RESULTS: We found a significant increase in the production of lysozyme, CRP and calprotectin in glucan-treated children. CONCLUSIONS: Short-term oral application of natural immunomodulator β-glucan significantly stimulated mucosal immunity of children with chronic respiratory problems.
Authors: Kenneth Hsu; Chantrakorn Champaiboon; Brian D Guenther; Brent S Sorenson; Ali Khammanivong; Karen F Ross; Carolyn L Geczy; Mark C Herzberg Journal: Antiinflamm Antiallergy Agents Med Chem Date: 2009-12-04
Authors: David D Tieu; Anju T Peters; Roderick G Carter; Roderick T Carter; Lydia Suh; David B Conley; Rakesh Chandra; James Norton; Leslie C Grammer; Kathleen E Harris; Atsushi Kato; Robert C Kern; Robert P Schleimer Journal: J Allergy Clin Immunol Date: 2010-03 Impact factor: 10.793
Authors: Daniel R Calabrese; Ping Wang; Tiffany Chong; Jonathan Hoover; Jonathan P Singer; Dara Torgerson; Steven R Hays; Jeffrey A Golden; Jasleen Kukreja; Daniel Dugger; Jason D Christie; John R Greenland Journal: JCI Insight Date: 2019-11-14
Authors: Jae Gil Lee; Young Sam Kim; Young Ju Lee; Hyeon Yeong Ahn; Minjoo Kim; Minkyung Kim; Min Jung Cho; Younsoo Cho; Jong Ho Lee Journal: Nutrients Date: 2016-06-02 Impact factor: 5.717
Authors: Martina Závorková; Vaclav Vetvicka; Josef Richter; Vlastimil Kral; Ivana Liehnova; Dobiasova L Rajnohova Journal: Open Biochem J Date: 2018-03-30