Literature DB >> 2531282

Evidence for glycosyl-phosphatidylinositol anchoring of Toxoplasma gondii major surface antigens.

S Tomavo1, R T Schwarz, J F Dubremetz.   

Abstract

The four major surface antigens of Toxoplasma gondii tachyzoites (P43, P35, P30, and P22) were made water soluble by phosphatidylinositol-specific phospholipase C (PI-PLC). These antigens were biosynthetically labeled with 3H-fatty acids, [3H]ethanolamine, and [3H]carbohydrates. Treatment of 3H-fatty-acid-labeled parasite lysates with PI-PLC removed the radioactive label from these antigens. A cross-reacting determinant was exposed on these antigens after PI-PLC treatment.

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Year:  1989        PMID: 2531282      PMCID: PMC362548          DOI: 10.1128/mcb.9.10.4576-4580.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  27 in total

1.  Surface antigens of Toxoplasma gondii.

Authors:  G Couvreur; A Sadak; B Fortier; J F Dubremetz
Journal:  Parasitology       Date:  1988-08       Impact factor: 3.234

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Journal:  J Clin Endocrinol Metab       Date:  1971-12       Impact factor: 5.958

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Authors:  P Couzineau; H Baufine-Ducrocq
Journal:  Ann Parasitol Hum Comp       Date:  1969 May-Jun

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Crossreacting determinants in the C-terminal region of trypanosome variant surface antigens.

Authors:  G A Cross
Journal:  Nature       Date:  1979-01-25       Impact factor: 49.962

6.  Toxoplasma gondii: purification of trophozoites propagated in cell culture.

Authors:  B G Grimwood; K Hechemy; R W Stevens
Journal:  Exp Parasitol       Date:  1979-10       Impact factor: 2.011

7.  Cell membrane, but not circulating, carcinoembryonic antigen is linked to a phosphatidylinositol-containing hydrophobic domain.

Authors:  F Jean; P Malapert; G Rougon; J Barbet
Journal:  Biochem Biophys Res Commun       Date:  1988-09-15       Impact factor: 3.575

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Authors:  E Handman; J W Goding; J S Remington
Journal:  J Immunol       Date:  1980-06       Impact factor: 5.422

9.  The major surface antigen, P30, of Toxoplasma gondii is anchored by a glycolipid.

Authors:  S D Nagel; J C Boothroyd
Journal:  J Biol Chem       Date:  1989-04-05       Impact factor: 5.157

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Authors:  E Vivier; A Petitprez
Journal:  J Cell Biol       Date:  1969-11       Impact factor: 10.539

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  30 in total

1.  Transmembrane insertion of the Toxoplasma gondii GRA5 protein occurs after soluble secretion into the host cell.

Authors:  L Lecordier; C Mercier; L D Sibley; M F Cesbron-Delauw
Journal:  Mol Biol Cell       Date:  1999-04       Impact factor: 4.138

2.  Phosphorylation of Toxoplasma gondii major surface antigens.

Authors:  S Tomavo; A Martinage; J F Dubremetz
Journal:  Parasitol Res       Date:  1992       Impact factor: 2.289

3.  Toxoplasmacidal activity of macrophages activated by recombinant major surface antigen (P30) of Toxoplasma gondii.

Authors:  A Makioka; A Kobayashi
Journal:  Infect Immun       Date:  1991-08       Impact factor: 3.441

4.  Characterization of bradyzoite-specific antigens of Toxoplasma gondii.

Authors:  S Tomavo; B Fortier; M Soete; C Ansel; D Camus; J F Dubremetz
Journal:  Infect Immun       Date:  1991-10       Impact factor: 3.441

Review 5.  Toxoplasma gondii: 25 years and 25 major advances for the field.

Authors:  John C Boothroyd
Journal:  Int J Parasitol       Date:  2009-07-01       Impact factor: 3.981

6.  The surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1.

Authors:  I D Manger; A B Hehl; J C Boothroyd
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

7.  Fractionation of membrane components from tachyzoite forms of Toxoplasma gondii: differential recognition by immunoglobulin M (IgM) and IgG present in sera from patients with acute or chronic toxoplasmosis.

Authors:  M Giraldo; H Cannizzaro; M A Ferguson; I C Almeida; R T Gazzinelli
Journal:  J Clin Microbiol       Date:  2000-04       Impact factor: 5.948

8.  Molecular cloning and expression of a gene encoding Cryptosporidium parvum glycoproteins gp40 and gp15.

Authors:  A M Cevallos; X Zhang; M K Waldor; S Jaison; X Zhou; S Tzipori; M R Neutra; H D Ward
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

9.  Expression, characterization, and serologic reactivity of recombinant surface antigen P22 of Toxoplasma gondii.

Authors:  S F Parmley; G D Sgarlato; J Mark; J B Prince; J S Remington
Journal:  J Clin Microbiol       Date:  1992-05       Impact factor: 5.948

10.  Evidence for N-linked glycosylation in Toxoplasma gondii.

Authors:  M Odenthal-Schnittler; S Tomavo; D Becker; J F Dubremetz; R T Schwarz
Journal:  Biochem J       Date:  1993-05-01       Impact factor: 3.857

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