Literature DB >> 25304194

Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding.

Liang Chen1, Barun Mathema2, Kalyan D Chavda1, Frank R DeLeo3, Robert A Bonomo4, Barry N Kreiswirth5.   

Abstract

Klebsiella pneumoniae carbapenemases (KPCs) were first identified in 1996 in the USA. Since then, regional outbreaks of KPC-producing K. pneumoniae (KPC-Kp) have occurred in the USA, and have spread internationally. Dissemination of blaKPC involves both horizontal transfer of blaKPC genes and plasmids, and clonal spread. Of epidemiological significance, the international spread of KPC-producing K. pneumoniae is primarily associated with a single multilocus sequence type (ST), ST258, and its related variants. However, the molecular factors contributing to the success of ST258 largely remain unclear. In this review, we discuss the recent progresses in understanding KPC-producing K. pneumoniae that are contributing to our knowledge of plasmid and genome composition and structure among the KPC epidemic clone, and we identify possible factors that influence its epidemiological success.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Klebsiella pneumoniae carbapenemase; ST258; carbapenem-resistant

Mesh：

Substances：

Year:  2014        PMID： 25304194      PMCID： PMC4365952          DOI： 10.1016/j.tim.2014.09.003

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  80 in total

Review 1.  Type IV pilin proteins: versatile molecular modules.

Authors:  Carmen L Giltner; Ylan Nguyen; Lori L Burrows
Journal:  Microbiol Mol Biol Rev       Date:  2012-12       Impact factor: 11.056

2.  KPC-4 Is encoded within a truncated Tn4401 in an IncL/M plasmid, pNE1280, isolated from Enterobacter cloacae and Serratia marcescens.

Authors:  Kendall A Bryant; Trevor C Van Schooneveld; Ishwor Thapa; Dhundy Bastola; Laurina O Williams; Thomas J Safranek; Steven H Hinrichs; Mark E Rupp; Paul D Fey
Journal:  Antimicrob Agents Chemother       Date:  2012-10-15       Impact factor: 5.191

3.  Complete genome sequence of Klebsiella pneumoniae 1084, a hypermucoviscosity-negative K1 clinical strain.

Authors:  Ann-Chi Lin; Tsai-Lien Liao; Yi-Chun Lin; Yi-Chyi Lai; Min-Chi Lu; Ying-Tsong Chen
Journal:  J Bacteriol       Date:  2012-11       Impact factor: 3.490

4.  Unique genes identified in the epidemic extremely drug-resistant KPC-producing Klebsiella pneumoniae sequence type 258.

Authors:  I Chmelnitsky; M Shklyar; O Hermesh; S Navon-Venezia; R Edgar; Y Carmeli
Journal:  J Antimicrob Chemother       Date:  2012-10-04       Impact factor: 5.790

Review 5.  Proliferation and significance of clinically relevant β-lactamases.

Authors:  Karen Bush
Journal:  Ann N Y Acad Sci       Date:  2013-01       Impact factor: 5.691

6.  Klebsiella pneumoniae resistant to third-generation cephalosporins in five African and two Vietnamese major towns: multiclonal population structure with two major international clonal groups, CG15 and CG258.

Authors:  S Breurec; N Guessennd; M Timinouni; T A H Le; V Cao; A Ngandjio; F Randrianirina; J M Thiberge; A Kinana; A Dufougeray; J D Perrier-Gros-Claude; P Boisier; B Garin; S Brisse
Journal:  Clin Microbiol Infect       Date:  2012-03-05       Impact factor: 8.067

Review 7.  Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions.

Authors:  L S Tzouvelekis; A Markogiannakis; M Psichogiou; P T Tassios; G L Daikos
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

8.  KPC-9, a novel carbapenemase from clinical specimens in Israel.

Authors:  Carlos Hidalgo-Grass; Gabriela Warburg; Violeta Temper; Shmuel Benenson; Allon E Moses; Colin Block; Jacob Strahilevitz
Journal:  Antimicrob Agents Chemother       Date:  2012-09-10       Impact factor: 5.191

9.  Comparative population analysis of Klebsiella pneumoniae strains with extended-spectrum β-lactamases colonizing patients in rehabilitation centers in four countries.

Authors:  A Baraniak; R Izdebski; J Fiett; E Sadowy; A Adler; M Kazma; J Salomon; C Lawrence; A Rossini; A Salvia; J Vidal Samso; J Fierro; M Paul; Y Lerman; S Malhotra-Kumar; C Lammens; H Goossens; W Hryniewicz; C Brun-Buisson; Y Carmeli; M Gniadkowski
Journal:  Antimicrob Agents Chemother       Date:  2013-02-12       Impact factor: 5.191

10.  Complete nucleotide sequences of blaKPC-4- and blaKPC-5-harboring IncN and IncX plasmids from Klebsiella pneumoniae strains isolated in New Jersey.

Authors:  Liang Chen; Kalyan D Chavda; Henry S Fraimow; José R Mediavilla; Roberto G Melano; Michael R Jacobs; Robert A Bonomo; Barry N Kreiswirth
Journal:  Antimicrob Agents Chemother       Date:  2012-10-31       Impact factor: 5.191
View more
  174 in total

1.  Genomic Characterization of Enterobacter cloacae Isolates from China That Coproduce KPC-3 and NDM-1 Carbapenemases.

Authors:  Hong Du; Liang Chen; Kalyan D Chavda; Ruchi Pandey; Haifang Zhang; Xiaofang Xie; Yi-Wei Tang; Barry N Kreiswirth
Journal:  Antimicrob Agents Chemother       Date:  2016-03-25       Impact factor: 5.191

2.  A Genomic Approach To Identify Klebsiella pneumoniae and Acinetobacter baumannii Strains with Enhanced Competitive Fitness in the Lungs during Multistrain Pneumonia.

Authors:  Mallory J Agard; Egon A Ozer; Andrew R Morris; Raul Piseaux; Alan R Hauser
Journal:  Infect Immun       Date:  2019-05-21       Impact factor: 3.441

3.  Diverse Vectors and Mechanisms Spread New Delhi Metallo-β-Lactamases among Carbapenem-Resistant Enterobacteriaceae in the Greater Boston Area.

Authors:  Nicole Pecora; Xiaomin Zhao; Kathleen Nudel; Maria Hoffmann; Ning Li; Andrew B Onderdonk; Deborah Yokoe; Eric Brown; Marc Allard; Lynn Bry
Journal:  Antimicrob Agents Chemother       Date:  2019-01-29       Impact factor: 5.191

4.  Global Dissemination of blaKPC into Bacterial Species beyond Klebsiella pneumoniae and In Vitro Susceptibility to Ceftazidime-Avibactam and Aztreonam-Avibactam.

Authors:  Krystyna M Kazmierczak; Douglas J Biedenbach; Meredith Hackel; Sharon Rabine; Boudewijn L M de Jonge; Samuel K Bouchillon; Daniel F Sahm; Patricia A Bradford
Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

5.  First report of an OXA-48-producing multidrug-resistant Proteus mirabilis strain from Gaza, Palestine.

Authors:  Liang Chen; Nahed Al Laham; Kalyan D Chavda; Jose R Mediavilla; Michael R Jacobs; Robert A Bonomo; Barry N Kreiswirth
Journal:  Antimicrob Agents Chemother       Date:  2015-04-20       Impact factor: 5.191

6.  Complete sequence of a bla(KPC)-harboring cointegrate plasmid isolated from Escherichia coli.

Authors:  Kalyan D Chavda; Liang Chen; Michael R Jacobs; Albert D Rojtman; Robert A Bonomo; Barry N Kreiswirth
Journal:  Antimicrob Agents Chemother       Date:  2015-03-09       Impact factor: 5.191

7.  Prevalence and drug resistance characteristics of carbapenem-resistant Enterobacteriaceae in Hangzhou, China.

Authors:  Yan Yang; Jian Chen; Di Lin; Xujian Xu; Jun Cheng; Changgui Sun
Journal:  Front Med       Date:  2017-07-08       Impact factor: 4.592

8.  Unlocking Tn3-family transposase activity in vitro unveils an asymetric pathway for transposome assembly.

Authors:  Emilien Nicolas; Cédric A Oger; Nathan Nguyen; Michaël Lambin; Amandine Draime; Sébastien C Leterme; Michael Chandler; Bernard F J Hallet
Journal:  Proc Natl Acad Sci U S A       Date:  2017-01-17       Impact factor: 11.205

9.  Genetic Environment of the blaKPC-2 Gene in a Klebsiella pneumoniae Isolate That May Have Been Imported to Russia from Southeast Asia.

Authors:  Vladimir Ageevets; Julia Sopova; Irina Lazareva; Maya Malakhova; Elena Ilina; Elena Kostryukova; Vladislav Babenko; Alessandra Carattoli; Yuri Lobzin; Alexander Uskov; Sergey Sidorenko
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

Review 10.  NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings.

Authors:  Wenjing Wu; Yu Feng; Guangmin Tang; Fu Qiao; Alan McNally; Zhiyong Zong
Journal:  Clin Microbiol Rev       Date:  2019-01-30       Impact factor: 26.132
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.