Literature DB >> 25298637

Hb Hope: A Rare Variant of Haemoglobin-Forged a Rise in HbA1c on Immunoturbidimetric Assay.

Bratati Singh1, Debasis Debadatta Behera1, Neelam Mehta1, Seema Das1.   

Abstract

Glycosylated hemoglobin (HbA1c) determination is a powerful means for assessing the evaluation and management of patients with diabetes mellitus. Hemoglobin (Hb) variants and chemically modified derivatives of Hb can affect the accuracy of measurement of HbA1c done by various analytical methods. We report a patient with a rare variant of Hb (Hb Hope) that caused an abnormally high value of HBA1c when assayed using immunoturbidimetric assay ("Tina-quant" 2nd generation assay) and also elucidate the nature of the variant.

Entities:  

Keywords:  Diabetes mellitus; Glycosylated hemoglobin; Immunoturbidimetric assay

Year:  2013        PMID： 25298637      PMCID： PMC4175701          DOI： 10.1007/s12291-013-0406-0

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  9 in total

1.  HEMOGLOBIN HOPE: A BETA CHAIN VARIANT.

Authors:  V MINNICHI; R J HILL; P D KHURI; M E ANDERSON
Journal:  Blood       Date:  1965-05       Impact factor: 22.113

2.  Effects of hemoglobin C and S traits on glycohemoglobin measurements by eleven methods.

Authors:  William L Roberts; Sekineh Safar-Pour; Barun K De; Curt L Rohlfing; Cas W Weykamp; Randie R Little
Journal:  Clin Chem       Date:  2005-02-03       Impact factor: 8.327

3.  Evaluation and interference study of hemoglobin A1c measured by turbidimetric inhibition immunoassay.

Authors:  J Chang; C Hoke; B Ettinger; G Penerian
Journal:  Am J Clin Pathol       Date:  1998-03       Impact factor: 2.493

Review 4.  Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin.

Authors:  L Bry; P C Chen; D B Sacks
Journal:  Clin Chem       Date:  2001-02       Impact factor: 8.327

5.  Approved IFCC reference method for the measurement of HbA1c in human blood.

Authors:  Jan-Olof Jeppsson; Uwe Kobold; John Barr; Andreas Finke; Wieland Hoelzel; Tadao Hoshino; Kor Miedema; Andrea Mosca; Pierluigi Mauri; Rita Paroni; Linda Thienpont; Masao Umemoto; Cas Weykamp
Journal:  Clin Chem Lab Med       Date:  2002-01       Impact factor: 3.694

6.  Hb Himeji or beta 140 (H18) Ala----Asp. A slightly unstable hemoglobin with increased beta N-terminal glycation.

Authors:  Y Ohba; T Miyaji; M Murakami; S Kadowaki; T Fujita; M Oimomi; H Hatanaka; K Ishikawa; S Baba; K Hitaka
Journal:  Hemoglobin       Date:  1986       Impact factor: 0.849

7.  Adaptation of latex-enhanced assay for percent glycohemoglobin to a Dade Dimension analyzer.

Authors:  P Holownia; E Bishop; D J Newman; W G John; C P Price
Journal:  Clin Chem       Date:  1997-01       Impact factor: 8.327

8.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.

Authors:  D M Nathan; S Genuth; J Lachin; P Cleary; O Crofford; M Davis; L Rand; C Siebert
Journal:  N Engl J Med       Date:  1993-09-30       Impact factor: 91.245

9.  Translating the A1C assay into estimated average glucose values.

Authors:  David M Nathan; Judith Kuenen; Rikke Borg; Hui Zheng; David Schoenfeld; Robert J Heine
Journal:  Diabetes Care       Date:  2008-06-07       Impact factor: 19.112
  9 in total
  3 in total

1.  Incidental Detection of Hemoglobin Variants During Evaluation of HbA1c.

Authors:  Jayashree D Kulkarni; Sweta Shivashanker
Journal:  Indian J Clin Biochem       Date:  2021-01-21

2.  Antidiabetic effects of Scrophularia striata ethanolic extract via suppression of Pdx1 and Ins1 expression in pancreatic tissues of diabetic rats.

Authors:  Armieti Babaiedarzi; Saba Ghanbari; Maryam Mehrad Seresht; Modara Nasiri
Journal:  Sci Rep       Date:  2022-06-13       Impact factor: 4.996

3.  Direct comparison of oligochaete erythrocruorins as potential blood substitutes.

Authors:  Devon Zimmerman; Matthew DiIusto; Jack Dienes; Osheiza Abdulmalik; Jacob J Elmer
Journal:  Bioeng Transl Med       Date:  2017-07-19
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.