| Literature DB >> 25295782 |
Abstract
Reinduction of fetal gene expression is characteristic of the failing adult heart. Han et al. (2014) demonstrate that a novel cluster of long noncoding RNAs, Myheart, protects the heart from pathological hypertrophy, involving a negative-feedback molecular circuit with the epigenetic Brg1 complex to inhibit fetal-gene reactivation.Entities:
Mesh:
Substances:
Year: 2014 PMID: 25295782 PMCID: PMC4886471 DOI: 10.1016/j.cmet.2014.09.011
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287