Literature DB >> 25276286

Increased postoperative complications after protective ileostomy closure delay: An institutional study.

Ines Rubio-Perez1, Miguel Leon1, Daniel Pastor1, Joaquin Diaz Dominguez1, Ramon Cantero1.   

Abstract

AIM: To study the morbidity and complications associated to ileostomy reversal in colorectal surgery patients, and if these are related to the time of closure.
METHODS: A retrospective analysis of 93 patients, who had undergone elective ileostomy closure between 2009 and 2013 was performed. Demographic, clinical and surgical variables were reviewed for analysis. All complications were recorded, and classified according to the Clavien-Dindo Classification. Statistical univariate and multivariate analysis was performed, setting a P value of 0.05 for significance.
RESULTS: The patients had a mean age of 60.3 years, 58% male. The main procedure for ileostomy creation was rectal cancer (56%), and 37% had received preoperative chemo-radiotherapy. The average delay from creation to closure of the ileostomy was 10.3 mo. Postoperative complications occurred in 40% of the patients, with 1% mortality. The most frequent were ileus (13%) and wound infection (13%). Pseudomembranous colitis appeared in 4%. Increased postoperative complications were associated with delay in ileostomy closure (P = 0.041). Male patients had more complications (P = 0.042), mainly wound infections (P = 0.007). Pseudomembranous colitis was also associated with the delay in ileostomy closure (P = 0.003). End-to-end intestinal anastomosis without resection was significantly associated with postoperative ileus (P = 0.037).
CONCLUSION: Although closure of a protective ileostomy is a fairly common surgical procedure, it has a high rate of complications, and this must be taken into account when the indication is made. The delay in stoma closure can increase the rate of complications in general, and specifically wound infections and colitis.

Entities:  

Keywords:  Colorectal surgery; Protective ileostomy; Stoma-related complications; Stomas; Surgical infections

Year:  2014        PMID: 25276286      PMCID: PMC4176777          DOI: 10.4240/wjgs.v6.i9.169

Source DB:  PubMed          Journal:  World J Gastrointest Surg


  28 in total

1.  Results of a nationwide prospective audit of stoma complications within 3 weeks of surgery.

Authors:  J Cottam; K Richards; A Hasted; A Blackman
Journal:  Colorectal Dis       Date:  2007-08-02       Impact factor: 3.788

Review 2.  The morbidity surrounding reversal of defunctioning ileostomies: a systematic review of 48 studies including 6,107 cases.

Authors:  Andre Chow; Henry S Tilney; Paraskevas Paraskeva; Santhini Jeyarajah; Emmanouil Zacharakis; Sanjay Purkayastha
Journal:  Int J Colorectal Dis       Date:  2009-02-17       Impact factor: 2.571

Review 3.  Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer.

Authors:  W S Tan; C L Tang; L Shi; K W Eu
Journal:  Br J Surg       Date:  2009-05       Impact factor: 6.939

4.  Diversion stoma after colorectal surgery: loop colostomy or ileostomy?

Authors:  Christian D Klink; Kosta Lioupis; Marcel Binnebösel; Daniel Kaemmer; Ivanna Kozubek; Jochen Grommes; Ulf P Neumann; Marc Jansen; Stefan Willis
Journal:  Int J Colorectal Dis       Date:  2011-01-11       Impact factor: 2.571

5.  When are defunctioning stomas in rectal cancer surgery really reversed? Results from a population-based single center experience.

Authors:  H Floodeen; R Lindgren; P Matthiessen
Journal:  Scand J Surg       Date:  2013-09-20       Impact factor: 2.360

6.  Morbidity of temporary loop ileostomy in patients with colorectal cancer.

Authors:  Andreas Thalheimer; Marco Bueter; Martin Kortuem; Arnulf Thiede; Detlef Meyer
Journal:  Dis Colon Rectum       Date:  2006-07       Impact factor: 4.585

7.  Morbidity after closure of a defunctioning loop ileostomy.

Authors:  A D'Haeninck; A M Wolthuis; F Penninckx; M D'Hondt; A D'Hoore
Journal:  Acta Chir Belg       Date:  2011 May-Jun       Impact factor: 1.090

8.  Subcutaneous gentamycin implant to reduce wound infections after loop-ileostomy closure: a randomized, double-blind, placebo-controlled trial.

Authors:  O Haase; W Raue; B Böhm; H Neuss; M Scharfenberg; W Schwenk
Journal:  Dis Colon Rectum       Date:  2005-11       Impact factor: 4.585

Review 9.  Systematic review and meta-analysis of published, randomized, controlled trials comparing suture anastomosis to stapled anastomosis for ileostomy closure.

Authors:  M S Sajid; L Craciunas; M K Baig; P Sains
Journal:  Tech Coloproctol       Date:  2013-05-17       Impact factor: 3.781

10.  Randomized clinical trial of intestinal ostomy takedown comparing pursestring wound closure vs conventional closure to eliminate the risk of wound infection.

Authors:  Daniel Camacho-Mauries; José Luis Rodriguez-Díaz; Noel Salgado-Nesme; Quintín H González; Omar Vergara-Fernández
Journal:  Dis Colon Rectum       Date:  2013-02       Impact factor: 4.585

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  15 in total

1.  Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis.

Authors:  Richard Garfinkle; Paul Savage; Marylise Boutros; Tara Landry; Pauline Reynier; Nancy Morin; Carol-Ann Vasilevsky; Kristian B Filion
Journal:  Surg Endosc       Date:  2019-04-17       Impact factor: 4.584

2.  Application of an enhanced recovery pathway for ileostomy closure: a case-control trial with surprising results.

Authors:  J Slieker; M Hübner; V Addor; C Duvoisin; N Demartines; D Hahnloser
Journal:  Tech Coloproctol       Date:  2018-05-03       Impact factor: 3.781

3.  Disparities in colostomy reversal after Hartmann's procedure for diverticulitis.

Authors:  M C Turner; M D Talbott; C Reed; Z Sun; M L Cox; B Ezekian; K L Sherman; C R Mantyh; J Migaly
Journal:  Tech Coloproctol       Date:  2019-04-30       Impact factor: 3.781

4.  Overwhelming Recurrent Clostridium difficile Infection after Reversal of Diverting Loop Ileostomy Created for Prior Fulminant C. difficile Colitis.

Authors:  Anna Z Fashandi; Scott R Ellis; Philip W Smith; Peter T Hallowell
Journal:  Am Surg       Date:  2016-08       Impact factor: 0.688

5.  Risk Factors for Postoperative Complications Following Diverting Loop Ileostomy Takedown.

Authors:  Anuradha R Bhama; Farwa Batool; Stacey D Collins; Jane Ferraro; Robert K Cleary
Journal:  J Gastrointest Surg       Date:  2017-10-02       Impact factor: 3.452

6.  Socioeconomic disparities in ostomy reversal among older adults with diverticulitis are more substantial among non-Hispanic Black patients.

Authors:  Trista D Reid; Riju Shrestha; Lucas Stone; Jared Gallaher; Anthony G Charles; Paula D Strassle
Journal:  Surgery       Date:  2021-04-28       Impact factor: 4.348

7.  Early closure of defunctioning stoma increases complications related to stoma closure after concurrent chemoradiotherapy and low anterior resection in patients with rectal cancer.

Authors:  Tzu-Chieh Yin; Hsiang-Lin Tsai; Ping-Fu Yang; Wei-Chih Su; Cheng-Jen Ma; Ching-Wen Huang; Ming-Yii Huang; Chun-Ming Huang; Jaw-Yuan Wang
Journal:  World J Surg Oncol       Date:  2017-04-11       Impact factor: 2.754

8.  Diverting Ileostomy Duration Is the Main Determinant of Ileostomy-Related Complications after Surgical Treatment of Rectum Cancer.

Authors:  Nadir Adnan Hacim; Ahmet Akbas; Serhat Meric; Yüksel Altinel; Onder Karabay; Erkan Yavuz
Journal:  J Oncol       Date:  2020-04-07       Impact factor: 4.375

9.  Early versus conventional stoma closure following bowel surgery: A randomized controlled trial.

Authors:  Thirugnanasambandam Nelson; Amuda R Pranavi; Sathasivam Sureshkumar; Gubbi S Sreenath; Vikram Kate
Journal:  Saudi J Gastroenterol       Date:  2018 Jan-Feb       Impact factor: 2.485

10.  A case of severe megacolon due to acquired isolated hypoganglionosis after low anterior resection for lower rectal cancer.

Authors:  Tetsuro Tominaga; Satoshi Nagayama; Manabu Takamatsu; Shun Miyanari; Toshiya Nagasaki; Tomohiro Yamaguchi; Takashi Akiyoshi; Tsuyoshi Konishi; Yoshiya Fujimoto; Yosuke Fukunaga; Masashi Ueno
Journal:  Clin J Gastroenterol       Date:  2019-12-11
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