Literature DB >> 25264321

National trends in the management of central cord syndrome: an analysis of 16,134 patients.

David W Brodell1, Amit Jain2, John C Elfar3, Addisu Mesfin4.   

Abstract

BACKGROUND CONTEXT: Central cord syndrome (CCS) is a common cause of incomplete spinal cord injury. However, to date, national trends in the management and mortality after CCS are not fully understood.
PURPOSE: To analyze how patient, surgical, and institutional factors influence surgical management and mortality after CCS. STUDY
DESIGN: A retrospective cohort analysis. PATIENT SAMPLE: The Nationwide Inpatient Sample (NIS) was queried for records of patients with a diagnosis of CCS from 2003 to 2010. OUTCOME MEASURES: They included in hospital mortality and surgical management, including anterior cervical decompression and fusion (ACDF), posterior cervical decompression and fusion (PCDF), and posterior cervical decompression (PCD).
METHODS: Using International Classification of Diseases, Ninth Revision, Clinical Modification codes, patient records with a diagnosis of CCS from 2003 to 2010 were selected from the NIS database and sorted by inpatient mortality and surgical management. Demographic information (age, gender, and race) and hospital characteristics were evaluated with χ(2)-tests for categorical variables and t tests for continuous variables. Multivariate logistic regression models controlled for confounding.
RESULTS: In this sample of 16,134 patients, a total of 39.7% of patients (6,351) underwent surgery. ACDF was most common (19.4%), followed by PCDF (7.4%) and PCD (6.8%). From 2003 to 2010, surgical management increased by an average of 40% each year. The overall inpatient mortality rate was 2.6%. Increasing age and comorbidities were associated with higher rates of patient mortality and a decreasing surgical rate (p<.01). Hospitals greater than 249 beds (p<.01) and the south (p<.01) were associated with a higher surgical rate. Rural hospitals (p<.01) and people in the second income quartile (p<.01) were associated with higher inpatient mortality.
CONCLUSIONS: Elderly patients with medical comorbidities are associated with a lower surgical rate and a higher mortality rate. Surgical management was more prevalent in the south and large hospitals. Mortality was higher in rural hospitals. It is important for surgeons to understand how patient, surgical, and institutional factors influence surgical management and mortality.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Central cord syndrome; Comorbidities; Demographics; Inpatient mortality; National database; Surgical management

Mesh:

Year:  2014        PMID: 25264321      PMCID: PMC4339306          DOI: 10.1016/j.spinee.2014.09.015

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  19 in total

1.  The long-term outcome after central cord syndrome: a study of the natural history.

Authors:  M L Newey; P K Sen; R D Fraser
Journal:  J Bone Joint Surg Br       Date:  2000-08

2.  Acute central cervical cord injury: the effect of age upon prognosis.

Authors:  L Y Dai
Journal:  Injury       Date:  2001-04       Impact factor: 2.586

Review 3.  The urgency of surgical decompression in acute central cord injuries with spondylosis and without instability.

Authors:  Brian Lenehan; Charles G Fisher; Alex Vaccaro; Michael Fehlings; Bizhan Aarabi; Marcel F Dvorak
Journal:  Spine (Phila Pa 1976)       Date:  2010-10-01       Impact factor: 3.468

4.  A histopathological analysis of the human cervical spinal cord in patients with acute traumatic central cord syndrome.

Authors:  O Jimenez; A Marcillo; A D Levi
Journal:  Spinal Cord       Date:  2000-09       Impact factor: 2.772

5.  Predictors of neurologic recovery in acute central cervical cord injury with only upper extremity impairment.

Authors:  Yoichiro Ishida; Toshikatsu Tominaga
Journal:  Spine (Phila Pa 1976)       Date:  2002-08-01       Impact factor: 3.468

Review 6.  Central cord syndrome.

Authors:  Douglas D Nowak; Joseph K Lee; Daniel E Gelb; Kornelis A Poelstra; Steven C Ludwig
Journal:  J Am Acad Orthop Surg       Date:  2009-12       Impact factor: 3.020

7.  Central cord syndrome in Ireland: the effect of age on clinical outcome.

Authors:  Brian Lenehan; John Street; Patrick O'Toole; Atar Siddiqui; Ashley Poynton
Journal:  Eur Spine J       Date:  2009-08-15       Impact factor: 3.134

8.  Trends in the treatment for traumatic central cord syndrome without bone injury in the United States from 2000 to 2009.

Authors:  Hiroyuki Yoshihara; Daisuke Yoneoka
Journal:  J Trauma Acute Care Surg       Date:  2013-09       Impact factor: 3.313

9.  Prevalence of obesity among adults from rural and urban areas of the United States: findings from NHANES (2005-2008).

Authors:  Christie A Befort; Niaman Nazir; Michael G Perri
Journal:  J Rural Health       Date:  2012-05-31       Impact factor: 4.333

10.  Early versus delayed decompression for traumatic cervical spinal cord injury: results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS).

Authors:  Michael G Fehlings; Alexander Vaccaro; Jefferson R Wilson; Anoushka Singh; David W Cadotte; James S Harrop; Bizhan Aarabi; Christopher Shaffrey; Marcel Dvorak; Charles Fisher; Paul Arnold; Eric M Massicotte; Stephen Lewis; Raja Rampersaud
Journal:  PLoS One       Date:  2012-02-23       Impact factor: 3.240

View more
  12 in total

1.  Management and prognosis of acute traumatic cervical central cord syndrome: systematic review and Spinal Cord Society-Spine Trauma Study Group position statement.

Authors:  P K Karthik Yelamarthy; H S Chhabra; Alex Vaccaro; Gayatri Vishwakarma; Patrick Kluger; Ankur Nanda; Rainer Abel; Wee Fu Tan; Brian Gardner; P Sarat Chandra; Sandip Chatterjee; Serdar Kahraman; Sait Naderi; Saumyajit Basu; Francois Theron
Journal:  Eur Spine J       Date:  2019-07-31       Impact factor: 3.134

Review 2.  Clinical Trials in Traumatic Spinal Cord Injury.

Authors:  Jayne Donovan; Steven Kirshblum
Journal:  Neurotherapeutics       Date:  2018-07       Impact factor: 7.620

3.  Central cord syndrome in a patient with systemic sclerosis and cervical calcinosis: case report and review of literature.

Authors:  Ha Son Nguyen; Abhishiek Sharma; Ninh Doan; Michael Gelsomino; Saman Shabani; Dennis Maiman
Journal:  Spinal Cord Ser Cases       Date:  2016-01-07

4.  A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.

Authors:  Kevin A Reinard; Diana M Cook; Hesham M Zakaria; Azam M Basheer; Victor W Chang; Muwaffak M Abdulhak
Journal:  Eur Spine J       Date:  2016-03-14       Impact factor: 3.134

Review 5.  The case for surgery of the injured spine in the management of traumatic cord injuries.

Authors:  I David Kaye; Alex R Vaccaro
Journal:  Spinal Cord Ser Cases       Date:  2018-02-22

6.  Traumatic spinal cord injuries in geriatric population: etiology, management, and complications.

Authors:  Karan Arul; Laurence Ge; Tochukwu Ikpeze; Avionna Baldwin; Addisu Mesfin
Journal:  J Spine Surg       Date:  2019-03

7.  Epidemiology and treatment of central cord syndrome in the United States.

Authors:  Dale N Segal; Zachary J Grabel; John G Heller; John M Rhee; Keith W Michael; S Tim Yoon; Amit Jain
Journal:  J Spine Surg       Date:  2018-12

8.  Diagnosis and management of traumatic cervical central spinal cord injury: A review.

Authors:  Nancy E Epstein; Renee Hollingsworth
Journal:  Surg Neurol Int       Date:  2015-05-07

Review 9.  Spinal Cord Injury in the Geriatric Population: Risk Factors, Treatment Options, and Long-Term Management.

Authors:  Tochukwu C Ikpeze; Addisu Mesfin
Journal:  Geriatr Orthop Surg Rehabil       Date:  2017-03-20

10.  Management of Acute Traumatic Central Cord Syndrome: A Narrative Review.

Authors:  Srikanth N Divi; Gregory D Schroeder; John J Mangan; Madeline Tadley; Wyatt L Ramey; Jetan H Badhiwala; Michael G Fehlings; F Cumhur Oner; Frank Kandziora; Lorin M Benneker; Emiliano N Vialle; Shanmuganathan Rajasekaran; Jens R Chapman; Alexander R Vaccaro
Journal:  Global Spine J       Date:  2019-05-08
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.