Literature DB >> 29479484

The case for surgery of the injured spine in the management of traumatic cord injuries.

I David Kaye1, Alex R Vaccaro1.   

Abstract

Spinal cord injury can be a life-altering trauma for patients and can be costly to patients and society alike. Generally recognized as biphasic, these injuries have both primary and secondary drivers. Although the primary insult is largely unavoidable, prevention of secondary injury mechanisms-and the resultant cascade-has been a target of substantial research. Continued spinal cord compression has been recognized as one of several deleterious secondary mechanisms, and decompressive and stabilization surgery has been routinely used for neuroprotection in this setting. Numerous biomechanical and animal studies have confirmed its potential utility. More recently, several high-quality randomized trials have concluded that early surgery for spinal cord injury improves rates of recovery when compared with delayed or nonoperative management. Herein, we argue that early surgery for spinal cord injury with continued cord compression offers significant benefit and should be undertaken when not contraindicated.

Entities:  

Year:  2018        PMID: 29479484      PMCID: PMC5823880          DOI: 10.1038/s41394-018-0043-1

Source DB:  PubMed          Journal:  Spinal Cord Ser Cases        ISSN: 2058-6124


  23 in total

1.  Effect of surgery on motor recovery following traumatic spinal cord injury.

Authors:  R L Waters; R H Adkins; J S Yakura; I Sie
Journal:  Spinal Cord       Date:  1996-04       Impact factor: 2.772

2.  Injuries of the cervical spine. II. Does anatomical reduction of the bony injuries improve the prognosis for spinal cord recovery?

Authors:  D M Dall
Journal:  S Afr Med J       Date:  1972-08-05

Review 3.  Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms.

Authors:  C H Tator; M G Fehlings
Journal:  J Neurosurg       Date:  1991-07       Impact factor: 5.115

4.  The influence of spinal canal narrowing and timing of decompression on neurologic recovery after spinal cord contusion in a rat model.

Authors:  J R Dimar; S D Glassman; G H Raque; Y P Zhang; C B Shields
Journal:  Spine (Phila Pa 1976)       Date:  1999-08-15       Impact factor: 3.468

5.  Neurologic outcome of early versus late surgery for cervical spinal cord injury.

Authors:  A R Vaccaro; R J Daugherty; T P Sheehan; S J Dante; J M Cotler; R A Balderston; G J Herbison; B E Northrup
Journal:  Spine (Phila Pa 1976)       Date:  1997-11-15       Impact factor: 3.468

6.  The effectiveness of surgery on the treatment of acute spinal cord injury and its relation to pharmacological treatment.

Authors:  M S Duh; M J Shepard; J E Wilberger; M B Bracken
Journal:  Neurosurgery       Date:  1994-08       Impact factor: 4.654

7.  The value of decompression for acute experimental spinal cord compression injury.

Authors:  E J Dolan; C H Tator; L Endrenyi
Journal:  J Neurosurg       Date:  1980-12       Impact factor: 5.115

8.  Apoptosis after traumatic human spinal cord injury.

Authors:  E Emery; P Aldana; M B Bunge; W Puckett; A Srinivasan; R W Keane; J Bethea; A D Levi
Journal:  J Neurosurg       Date:  1998-12       Impact factor: 5.115

Review 9.  Does early decompression improve neurological outcome of spinal cord injured patients? Appraisal of the literature using a meta-analytical approach.

Authors:  G La Rosa; A Conti; S Cardali; F Cacciola; F Tomasello
Journal:  Spinal Cord       Date:  2004-09       Impact factor: 2.772

10.  Early versus late surgery for traumatic spinal cord injury: the results of a prospective Canadian cohort study.

Authors:  J R Wilson; A Singh; C Craven; M C Verrier; B Drew; H Ahn; M Ford; M G Fehlings
Journal:  Spinal Cord       Date:  2012-05-08       Impact factor: 2.772

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  2 in total

1.  Awards and updates.

Authors:  Marcalee Alexander
Journal:  Spinal Cord Ser Cases       Date:  2018-06-25

2.  Multilevel critical stenosis with minimal functional deficits: a case of cervical spondylotic myelopathy.

Authors:  Anup K Gangavalli; Ajith Malige; Gbolabo Sokunbi
Journal:  Spinal Cord Ser Cases       Date:  2018-11-19
  2 in total

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