| Literature DB >> 25261302 |
Ann C Palmenberg1, James E Gern.
Abstract
The historical classification of human rhinoviruses (RV) by serotyping has been replaced by a logical system of comparative sequencing. Given that strains must diverge within their capsid sequenced by a reasonable degree (>12-13 % pairwise base identities) before becoming immunologically distinct, the new nomenclature system makes allowances for the addition of new, future types, without compromising historical designations. Currently, three species, the RV-A, RV-B, and RV-C, are recognized. Of these, the RV-C, discovered in 2006, are the most unusual in terms of capsid structure, receptor use, and association with severe disease in children.Entities:
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Year: 2015 PMID: 25261302 PMCID: PMC4441521 DOI: 10.1007/978-1-4939-1571-2_1
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745