| Literature DB >> 33084935 |
Kim Tien Ng1,2, Yutaka Takebe3,4, Adeeba Kamarulzaman1, Kok Keng Tee5,6.
Abstract
Genome sequences of members of a potential fourth rhinovirus (RV) species, provisionally denoted as rhinovirus A clade D, from patients with acute respiratory infection were determined. Bayesian coalescent analysis estimated that clade D emerged around the 1940s and diverged further around 2006-2007 into two distinctive sublineages (RV-A8-like and RV-A45-like) that harbored unique "clade-defining" substitutions. Similarity plots and bootscan mapping revealed a recombination breakpoint located in the 5'-UTR region of members of the RV-A8-like sublineage. Phylogenetic reconstruction revealed the distribution of clade D viruses in the Asia Pacific region and in Europe, underlining its worldwide distribution.Entities:
Year: 2020 PMID: 33084935 DOI: 10.1007/s00705-020-04855-5
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574