Bruce S Pyenson1, Claudia I Henschke2, David F Yankelevitz3, Rowena Yip4, Ellynne Dec5. 1. Principal & Consulting Actuary, Milliman, Inc, New York. 2. Clinical Professor, Radiology, Icahn School of Medicine at Mount Sinai. 3. Professor, Radiology, Icahn School of Medicine at Mount Sinai. 4. Senior Biostatistician, Icahn School of Medicine at Mount Sinai, New York. 5. Actuary, Milliman, Inc, New York.
Abstract
BACKGROUND: By a wide margin, lung cancer is the most significant cause of cancer death in the United States and worldwide. The incidence of lung cancer increases with age, and Medicare beneficiaries are often at increased risk. Because of its demonstrated effectiveness in reducing mortality, lung cancer screening with low-dose computed tomography (LDCT) imaging will be covered without cost-sharing starting January 1, 2015, by nongrandfathered commercial plans. Medicare is considering coverage for lung cancer screening. OBJECTIVE: To estimate the cost and cost-effectiveness (ie, cost per life-year saved) of LDCT lung cancer screening of the Medicare population at high risk for lung cancer. METHODS: Medicare costs, enrollment, and demographics were used for this study; they were derived from the 2012 Centers for Medicare & Medicaid Services (CMS) beneficiary files and were forecast to 2014 based on CMS and US Census Bureau projections. Standard life and health actuarial techniques were used to calculate the cost and cost-effectiveness of lung cancer screening. The cost, incidence rates, mortality rates, and other parameters chosen by the authors were taken from actual Medicare data, and the modeled screenings are consistent with Medicare processes and procedures. RESULTS: Approximately 4.9 million high-risk Medicare beneficiaries would meet criteria for lung cancer screening in 2014. Without screening, Medicare patients newly diagnosed with lung cancer have an average life expectancy of approximately 3 years. Based on our analysis, the average annual cost of LDCT lung cancer screening in Medicare is estimated to be $241 per person screened. LDCT screening for lung cancer in Medicare beneficiaries aged 55 to 80 years with a history of ≥30 pack-years of smoking and who had smoked within 15 years is low cost, at approximately $1 per member per month. This assumes that 50% of these patients were screened. Such screening is also highly cost-effective, at <$19,000 per life-year saved. CONCLUSION: If all eligible Medicare beneficiaries had been screened and treated consistently from age 55 years, approximately 358,134 additional individuals with current or past lung cancer would be alive in 2014. LDCT screening is a low-cost and cost-effective strategy that fits well within the standard Medicare benefit, including its claims payment and quality monitoring.
BACKGROUND: By a wide margin, lung cancer is the most significant cause of cancer death in the United States and worldwide. The incidence of lung cancer increases with age, and Medicare beneficiaries are often at increased risk. Because of its demonstrated effectiveness in reducing mortality, lung cancer screening with low-dose computed tomography (LDCT) imaging will be covered without cost-sharing starting January 1, 2015, by nongrandfathered commercial plans. Medicare is considering coverage for lung cancer screening. OBJECTIVE: To estimate the cost and cost-effectiveness (ie, cost per life-year saved) of LDCT lung cancer screening of the Medicare population at high risk for lung cancer. METHODS: Medicare costs, enrollment, and demographics were used for this study; they were derived from the 2012 Centers for Medicare & Medicaid Services (CMS) beneficiary files and were forecast to 2014 based on CMS and US Census Bureau projections. Standard life and health actuarial techniques were used to calculate the cost and cost-effectiveness of lung cancer screening. The cost, incidence rates, mortality rates, and other parameters chosen by the authors were taken from actual Medicare data, and the modeled screenings are consistent with Medicare processes and procedures. RESULTS: Approximately 4.9 million high-risk Medicare beneficiaries would meet criteria for lung cancer screening in 2014. Without screening, Medicare patients newly diagnosed with lung cancer have an average life expectancy of approximately 3 years. Based on our analysis, the average annual cost of LDCT lung cancer screening in Medicare is estimated to be $241 per person screened. LDCT screening for lung cancer in Medicare beneficiaries aged 55 to 80 years with a history of ≥30 pack-years of smoking and who had smoked within 15 years is low cost, at approximately $1 per member per month. This assumes that 50% of these patients were screened. Such screening is also highly cost-effective, at <$19,000 per life-year saved. CONCLUSION: If all eligible Medicare beneficiaries had been screened and treated consistently from age 55 years, approximately 358,134 additional individuals with current or past lung cancer would be alive in 2014. LDCT screening is a low-cost and cost-effective strategy that fits well within the standard Medicare benefit, including its claims payment and quality monitoring.
Authors: Claudia I Henschke; David F Yankelevitz; Rowena Yip; Anthony P Reeves; Ali Farooqi; Dongming Xu; James P Smith; Daniel M Libby; Mark W Pasmantier; Olli S Miettinen Journal: Radiology Date: 2012-03-27 Impact factor: 11.105
Authors: John K Field; Robert A Smith; Denise R Aberle; Matthijs Oudkerk; David R Baldwin; David Yankelevitz; Jesper Holst Pedersen; Scott James Swanson; William D Travis; Ignacio I Wisbuba; Masayuki Noguchi; Jim L Mulshine Journal: J Thorac Oncol Date: 2012-01 Impact factor: 15.609
Authors: Edward F Patz; Paul Pinsky; Constantine Gatsonis; Jorean D Sicks; Barnett S Kramer; Martin C Tammemägi; Caroline Chiles; William C Black; Denise R Aberle Journal: JAMA Intern Med Date: 2014-02-01 Impact factor: 21.873
Authors: G Veronesi; P Maisonneuve; C Rampinelli; R Bertolotti; F Petrella; L Spaggiari; M Bellomi Journal: Lung Cancer Date: 2013-09-08 Impact factor: 5.705
Authors: Cary P Gross; Jessica B Long; Joseph S Ross; Maysa M Abu-Khalaf; Rong Wang; Brigid K Killelea; Heather T Gold; Anees B Chagpar; Xiaomei Ma Journal: JAMA Intern Med Date: 2013-02-11 Impact factor: 21.873
Authors: Bradley D Allen; Mark L Schiebler; Gregor Sommer; Hans-Ulrich Kauczor; Juergen Biederer; Timothy J Kruser; James C Carr; Gordon Hazen Journal: Eur Radiol Date: 2019-11-20 Impact factor: 5.315
Authors: Joshua A Roth; Sean D Sullivan; Bernardo H L Goulart; Arliene Ravelo; Joanna C Sanderson; Scott D Ramsey Journal: J Oncol Pract Date: 2015-05-05 Impact factor: 3.840
Authors: Matthijs Oudkerk; ShiYuan Liu; Marjolein A Heuvelmans; Joan E Walter; John K Field Journal: Nat Rev Clin Oncol Date: 2020-10-12 Impact factor: 66.675