Literature DB >> 25237423

Offering lung cancer screening to high-risk medicare beneficiaries saves lives and is cost-effective: an actuarial analysis.

Bruce S Pyenson1, Claudia I Henschke2, David F Yankelevitz3, Rowena Yip4, Ellynne Dec5.   

Abstract

BACKGROUND: By a wide margin, lung cancer is the most significant cause of cancer death in the United States and worldwide. The incidence of lung cancer increases with age, and Medicare beneficiaries are often at increased risk. Because of its demonstrated effectiveness in reducing mortality, lung cancer screening with low-dose computed tomography (LDCT) imaging will be covered without cost-sharing starting January 1, 2015, by nongrandfathered commercial plans. Medicare is considering coverage for lung cancer screening.
OBJECTIVE: To estimate the cost and cost-effectiveness (ie, cost per life-year saved) of LDCT lung cancer screening of the Medicare population at high risk for lung cancer.
METHODS: Medicare costs, enrollment, and demographics were used for this study; they were derived from the 2012 Centers for Medicare & Medicaid Services (CMS) beneficiary files and were forecast to 2014 based on CMS and US Census Bureau projections. Standard life and health actuarial techniques were used to calculate the cost and cost-effectiveness of lung cancer screening. The cost, incidence rates, mortality rates, and other parameters chosen by the authors were taken from actual Medicare data, and the modeled screenings are consistent with Medicare processes and procedures.
RESULTS: Approximately 4.9 million high-risk Medicare beneficiaries would meet criteria for lung cancer screening in 2014. Without screening, Medicare patients newly diagnosed with lung cancer have an average life expectancy of approximately 3 years. Based on our analysis, the average annual cost of LDCT lung cancer screening in Medicare is estimated to be $241 per person screened. LDCT screening for lung cancer in Medicare beneficiaries aged 55 to 80 years with a history of ≥30 pack-years of smoking and who had smoked within 15 years is low cost, at approximately $1 per member per month. This assumes that 50% of these patients were screened. Such screening is also highly cost-effective, at <$19,000 per life-year saved.
CONCLUSION: If all eligible Medicare beneficiaries had been screened and treated consistently from age 55 years, approximately 358,134 additional individuals with current or past lung cancer would be alive in 2014. LDCT screening is a low-cost and cost-effective strategy that fits well within the standard Medicare benefit, including its claims payment and quality monitoring.

Entities:  

Year:  2014        PMID: 25237423      PMCID: PMC4163779     

Source DB:  PubMed          Journal:  Am Health Drug Benefits        ISSN: 1942-2962


  27 in total

1.  The journal's policy on cost-effectiveness analyses.

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Journal:  N Engl J Med       Date:  1994-09-08       Impact factor: 91.245

2.  Screening for lung cancer with low-dose helical computed tomography: anti-lung cancer association project.

Authors:  Tomotaka Sobue; Noriyuki Moriyama; Masahiro Kaneko; Masahiko Kusumoto; Toshiaki Kobayashi; Ryosuke Tsuchiya; Ryutaro Kakinuma; Hironobu Ohmatsu; Kanji Nagai; Hiroyuki Nishiyama; Eisuke Matsui; Kenji Eguchi
Journal:  J Clin Oncol       Date:  2002-02-15       Impact factor: 44.544

3.  Lung cancer screening and smoking cessation: a teachable moment?

Authors:  Stephen A Deppen; Eric L Grogan; Melinda C Aldrich; Pierre P Massion
Journal:  J Natl Cancer Inst       Date:  2014-05-28       Impact factor: 13.506

4.  Lung cancers diagnosed at annual CT screening: volume doubling times.

Authors:  Claudia I Henschke; David F Yankelevitz; Rowena Yip; Anthony P Reeves; Ali Farooqi; Dongming Xu; James P Smith; Daniel M Libby; Mark W Pasmantier; Olli S Miettinen
Journal:  Radiology       Date:  2012-03-27       Impact factor: 11.105

5.  International Association for the Study of Lung Cancer Computed Tomography Screening Workshop 2011 report.

Authors:  John K Field; Robert A Smith; Denise R Aberle; Matthijs Oudkerk; David R Baldwin; David Yankelevitz; Jesper Holst Pedersen; Scott James Swanson; William D Travis; Ignacio I Wisbuba; Masayuki Noguchi; Jim L Mulshine
Journal:  J Thorac Oncol       Date:  2012-01       Impact factor: 15.609

6.  Overdiagnosis in low-dose computed tomography screening for lung cancer.

Authors:  Edward F Patz; Paul Pinsky; Constantine Gatsonis; Jorean D Sicks; Barnett S Kramer; Martin C Tammemägi; Caroline Chiles; William C Black; Denise R Aberle
Journal:  JAMA Intern Med       Date:  2014-02-01       Impact factor: 21.873

7.  Computed tomography screening for lung cancer: results of ten years of annual screening and validation of cosmos prediction model.

Authors:  G Veronesi; P Maisonneuve; C Rampinelli; R Bertolotti; F Petrella; L Spaggiari; M Bellomi
Journal:  Lung Cancer       Date:  2013-09-08       Impact factor: 5.705

8.  Definition of a positive test result in computed tomography screening for lung cancer: a cohort study.

Authors:  Claudia I Henschke; Rowena Yip; David F Yankelevitz; James P Smith
Journal:  Ann Intern Med       Date:  2013-02-19       Impact factor: 25.391

9.  The cost of breast cancer screening in the Medicare population.

Authors:  Cary P Gross; Jessica B Long; Joseph S Ross; Maysa M Abu-Khalaf; Rong Wang; Brigid K Killelea; Heather T Gold; Anees B Chagpar; Xiaomei Ma
Journal:  JAMA Intern Med       Date:  2013-02-11       Impact factor: 21.873

10.  Five-year lung cancer survival: which advanced stage nonsmall cell lung cancer patients attain long-term survival?

Authors:  Tina Wang; Rebecca A Nelson; Alicia Bogardus; Frederic W Grannis
Journal:  Cancer       Date:  2010-03-15       Impact factor: 6.860

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  27 in total

Review 1.  2016 reflections on the favorable cost-benefit of lung cancer screening.

Authors:  Bruce Pyenson; Gabriela Dieguez
Journal:  Ann Transl Med       Date:  2016-04

2.  Population health's unanimity on lung cancer screening: far ahead of medical advice.

Authors:  Bruce Pyenson; Claudia I Henschke; David F Yankelevitz
Journal:  Ann Transl Med       Date:  2017-09

3.  Cost-effectiveness of lung MRI in lung cancer screening.

Authors:  Bradley D Allen; Mark L Schiebler; Gregor Sommer; Hans-Ulrich Kauczor; Juergen Biederer; Timothy J Kruser; James C Carr; Gordon Hazen
Journal:  Eur Radiol       Date:  2019-11-20       Impact factor: 5.315

4.  State-Level Variations in the Utilization of Lung Cancer Screening Among Medicare Fee-for-Service Beneficiaries: An Analysis of the 2015 to 2017 Physician and Other Supplier Data.

Authors:  Bian Liu; Kavita Dharmarajan; Claudia I Henschke; Emanuela Taioli
Journal:  Chest       Date:  2019-11-22       Impact factor: 9.410

5.  Projected Clinical, Resource Use, and Fiscal Impacts of Implementing Low-Dose Computed Tomography Lung Cancer Screening in Medicare.

Authors:  Joshua A Roth; Sean D Sullivan; Bernardo H L Goulart; Arliene Ravelo; Joanna C Sanderson; Scott D Ramsey
Journal:  J Oncol Pract       Date:  2015-05-05       Impact factor: 3.840

6.  Offering lung cancer screening to high-risk medicare beneficiaries saves lives and is cost-effective: an actuarial analysis.

Authors:  Bruce S Pyenson; Claudia I Henschke; David F Yankelevitz; Rowena Yip; Ellynne Dec
Journal:  Am Health Drug Benefits       Date:  2014-08

Review 7.  Lung cancer LDCT screening and mortality reduction - evidence, pitfalls and future perspectives.

Authors:  Matthijs Oudkerk; ShiYuan Liu; Marjolein A Heuvelmans; Joan E Walter; John K Field
Journal:  Nat Rev Clin Oncol       Date:  2020-10-12       Impact factor: 66.675

Review 8.  Implementing lung cancer screening in the real world: opportunity, challenges and solutions.

Authors:  Robert J Optican; Caroline Chiles
Journal:  Transl Lung Cancer Res       Date:  2015-08

Review 9.  Risk factors assessment and risk prediction models in lung cancer screening candidates.

Authors:  Mariusz Adamek; Ewa Wachuła; Sylwia Szabłowska-Siwik; Agnieszka Boratyn-Nowicka; Damian Czyżewski
Journal:  Ann Transl Med       Date:  2016-04

10.  Promoting Clinical Conversations about Lung Cancer Screening: Exploring the Role of Perceived Online Social Support.

Authors:  Samantha R Paige; Ramzi G Salloum; Janice L Krieger; Maribeth Williams; Wei Xue; Babette Brumback
Journal:  J Health Commun       Date:  2020-10-29
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