Literature DB >> 25236434

Significance of fragmented QRS complexes for identifying left ventricular hypertrophy in patients with hypertension.

Baowei Zhang1, Ya Zhen, Dongli Shen, Guohui Zhang.   

Abstract

BACKGROUND: Fragmented QRS complexes (fQRS) were associated with left ventricular mass (LVM) in hypertensive patients. Our study aimed to investigate the association between fQRS and left ventricular hypertrophy (LVH) in hypertensive patients.
METHODS: Two hundred thirty-six hypertensive patients were divided into fQRS group and non-fQRS group. fQRS were defined as the presence of an additional R wave, notching in the R or S wave, or the presence of >1 R' in two contiguous leads. Echocardiography was used to detect LVH.
RESULTS: Patients with fQRS had higher levels of LVM than patients without fQRS (181.55 ± 65.64 g vs. 149.21 ± 35.08 g, P < 0.001). Receiver operating characteristic curves showed areas under the curve was 0.62 for fQRS (95% CI 0.54-0.69, P = 0.003). In univariate analyses, the presence of fQRS on ECG was positively associated with LVM. Multiple regression analyses found fQRS was associated with LVM, independently.
CONCLUSION: fQRS is a common electrocardiographic phenomenon in patients with hypertension. Although the diagnostic value for LVH is limited, the presence of fQRS on ECG is associated with a higher risk for worse LVH.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  fragmented QRS; hypertension; left ventricular hypertrophy; left ventricular mass

Mesh:

Year:  2014        PMID: 25236434      PMCID: PMC6931480          DOI: 10.1111/anec.12212

Source DB:  PubMed          Journal:  Ann Noninvasive Electrocardiol        ISSN: 1082-720X            Impact factor:   1.468


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