Literature DB >> 31451958

Fragmented QRS as a Marker of Myocardial Fibrosis in Hypertension: a Systematic Review.

Mehmet Eyuboglu1.   

Abstract

PURPOSE OF REVIEW: Hypertension cause damage in cardiac structure and induce pathological myocardial fibrosis that leads to hypertensive cardiomyopathy. A narrow fragmented QRS complex (fQRS) is associated with myocardial fibrosis and scar tissue in various cardiovascular diseases. It is also associated with myocardial fibrosis in hypertensive patients even in the absence of any structural heart diseases. This article aimed to demonstrate importance and usefulness of fQRS in hypertensive patients. RECENT
FINDINGS: Current evidence suggest that the frequency of fQRS is significantly higher in hypertensive patients compared to normotensives. Also, fQRS seems to be a predictor of left ventricular hypertrophy, increased systolic blood pressure, non-dipping, deterioration of the left ventricular geometry, and worse systolic and diastolic functions in hypertensive patients. As a simple and easy detectable electrocardiographic finding, fQRS may indicate myocardial fibrosis, uncontrolled blood pressure, and deteriorated cardiac structure in hypertensive patients even in the absence of other structural heart diseases, and may also be useful to predict high-risk hypertensives.

Entities:  

Keywords:  Electrocardiography; Fibrosis; Fragmented QRS; Hypertension; Left ventricular hypertrophy

Mesh:

Year:  2019        PMID: 31451958     DOI: 10.1007/s11906-019-0982-3

Source DB:  PubMed          Journal:  Curr Hypertens Rep        ISSN: 1522-6417            Impact factor:   5.369


  38 in total

Review 1.  Prognostic value of ambulatory blood pressure : current evidence and clinical implications.

Authors:  P Verdecchia
Journal:  Hypertension       Date:  2000-03       Impact factor: 10.190

Review 2.  Predictive role of the nighttime blood pressure.

Authors:  Tine W Hansen; Yan Li; José Boggia; Lutgarde Thijs; Tom Richart; Jan A Staessen
Journal:  Hypertension       Date:  2010-11-15       Impact factor: 10.190

3.  Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease.

Authors:  Mithilesh K Das; Bilal Khan; Sony Jacob; Awaneesh Kumar; Jo Mahenthiran
Journal:  Circulation       Date:  2006-05-22       Impact factor: 29.690

4.  Fragmented QRS on a 12-lead ECG: a predictor of mortality and cardiac events in patients with coronary artery disease.

Authors:  Mithilesh Kumar Das; Chandan Saha; Hicham El Masry; Jonathan Peng; Gopi Dandamudi; Jo Mahenthiran; Paul McHenry; Douglas P Zipes
Journal:  Heart Rhythm       Date:  2007-08-01       Impact factor: 6.343

Review 5.  QRS fragmentation: diagnostic and prognostic significance.

Authors:  Grzegorz Pietrasik; Wojciech Zaręba
Journal:  Cardiol J       Date:  2012       Impact factor: 2.737

6.  Nighttime blood pressure dipping: the role of the sympathetic nervous system.

Authors:  Andrew Sherwood; Patrick R Steffen; James A Blumenthal; Cynthia Kuhn; Alan L Hinderliter
Journal:  Am J Hypertens       Date:  2002-02       Impact factor: 2.689

7.  Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy.

Authors:  Mithilesh Kumar Das; Waddah Maskoun; Changyu Shen; Mark A Michael; Hussam Suradi; Mona Desai; Roopa Subbarao; Deepak Bhakta
Journal:  Heart Rhythm       Date:  2009-10-02       Impact factor: 6.343

Review 8.  Prevalence of electrocardiographic left ventricular hypertrophy in human hypertension: an updated review.

Authors:  Cesare Cuspidi; Marta Rescaldani; Carla Sala; Francesca Negri; Guido Grassi; Giuseppe Mancia
Journal:  J Hypertens       Date:  2012-11       Impact factor: 4.844

9.  Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.

Authors:  Sarah Lewington; Robert Clarke; Nawab Qizilbash; Richard Peto; Rory Collins
Journal:  Lancet       Date:  2002-12-14       Impact factor: 79.321

Review 10.  Mechanisms of cardiac fibrosis in hypertension.

Authors:  Javier Díez
Journal:  J Clin Hypertens (Greenwich)       Date:  2007-07       Impact factor: 3.738

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  5 in total

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Authors:  Goran Koracevic; Milovan Stojanovic; Dragan Lovic; Marija Zdravkovic; Dejan Sakac
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2.  Relationship Between Fragmented QRS Complex and Long-Term Cardiovascular Outcome in Patients with Essential Hypertension.

Authors:  Mehmet Altunova; Hamdi Püşüroğlu; Muammer Karakayalı; Ahmet Anıl Şahin; Ali Rıza Demir; Emre Yılmaz; Ahmet Yaşar Çizgici; Mehmet Ertürk
Journal:  Anatol J Cardiol       Date:  2022-06       Impact factor: 1.475

3.  Electrocardiographic Patterns of Depolarization Abnormalities Help to Identify Reduced Left Ventricular Ejection Fraction.

Authors:  Maria Gordeeva; Irina Serdiukova; Alexander Krasichkov; Elena Parmon
Journal:  Diagnostics (Basel)       Date:  2022-08-21

Review 4.  Missing Link between Molecular Aspects of Ventricular Arrhythmias and QRS Complex Morphology in Left Ventricular Hypertrophy.

Authors:  Ljuba Bacharova
Journal:  Int J Mol Sci       Date:  2019-12-19       Impact factor: 5.923

Review 5.  High prevalence of fragmented QRS on electrocardiography in Japanese patients with diabetes irrespective of metabolic syndrome.

Authors:  Kunimasa Yagi; Yoshiki Nagata; Takashi Yamagami; Daisuke Chujo; Miki Kamigishi; Maki Yokoyama-Nakagawa; Masataka Shikata; Asako Enkaku; Akiko Takikawa-Nishida; Hisae Honoki; Shiho Fujisaka; Hideki Origasa; Kazuyuki Tobe
Journal:  J Diabetes Investig       Date:  2021-03-02       Impact factor: 4.232

  5 in total

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