Literature DB >> 25217397

Association between postprandial symptoms and gastric emptying after sleeve gastrectomy.

Jan S Burgerhart1, Pim W J van Rutte, Michela A L Edelbroek, Dirk N J Wyndaele, Johannes F Smulders, Paul C van de Meeberg, Peter D Siersema, André J P M Smout.   

Abstract

BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric procedure. However, postprandial symptoms can compromise its beneficial effect. It is not known if a changed gastric emptying and these symptoms are related. This study aimed to assess the association between postprandial symptoms and the gastric emptying pattern after LSG.
METHODS: A gastric emptying study with a solid and liquid meal component was performed in the second year after LSG. Before the test, symptoms were assessed using a standardized questionnaire, and during the test, symptoms were scored on a visual analog scale (VAS). Gastric emptying results were expressed as lag phase, half time of gastric emptying (T½), and caloric emptying rate/minute.
RESULTS: Twenty patients (14 F/6 M; age 45.6 ± 7.7 years, weight 93.4 ± 28.2 kg, BMI 31.6 ± 8.1 kg/m(2)) participated in this study; 13 had a low symptom score (≤9, group I), 7 a high symptom score (≥18, group II). VAS scores for epigastric pain, nausea, and belching were significantly higher in group II. Lag phase (solid) was 6.4 ± 4.5 min in group I, 7.3 ± 6.3 in group II (p = 0.94); T½ (solid) was 40.6 ± 10.0 min in group I, 34.4 ± 9.3 in group II (p = 0.27); caloric emptying rate was 3.9 ± 0.6 kcal/min in group I, 3.9 ± 1.0 kcal/min in group II (p = 0.32).
CONCLUSIONS: Patients with postprandial symptoms after LSG reported more symptoms during the gastric emptying study than patients without symptoms. However, there was no difference between gastric emptying characteristics between both groups, suggesting that abnormal gastric emptying is not a major determinant of postprandial symptoms after LSG.

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Year:  2015        PMID: 25217397     DOI: 10.1007/s11695-014-1410-z

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  20 in total

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4.  Clinical significance of scintigraphic rapid gastric emptying.

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6.  Symptoms suggestive of dumping syndrome after provocation in patients after laparoscopic sleeve gastrectomy.

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7.  Long-term effects of laparoscopic sleeve gastrectomy in morbidly obese subjects with type 2 diabetes mellitus.

Authors:  Jayashree S Todkar; Shashank S Shah; Poonam S Shah; Jayashri Gangwani
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8.  In functional dyspepsia, hypersensitivity to postprandial distention correlates with meal-related symptom severity.

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9.  Gastric emptying is not affected by sleeve gastrectomy--scintigraphic evaluation of gastric emptying after sleeve gastrectomy without removal of the gastric antrum.

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Journal:  Obes Surg       Date:  2008-12-17       Impact factor: 4.129

10.  Laparoscopic sleeve gastrectomy: standardized technique of a potential stand-alone bariatric procedure in morbidly obese patients.

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  6 in total

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2.  A Higher Preoperative Glycemic Profile Is Associated with Rapid Gastric Emptying After Sleeve Gastrectomy for Obese Subjects.

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Review 5.  Impact of Laparoscopic Sleeve Gastrectomy on Gastrointestinal Motility.

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Review 6.  Gastric Sensory and Motor Functions and Energy Intake in Health and Obesity-Therapeutic Implications.

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