Literature DB >> 25217092

Surgical site infections (SSIs) after stoma reversal (SR): risk factors, implications, and protective strategies.

Daniel I Chu1, Christopher R Schlieve, Dorin T Colibaseanu, Paul J Simpson, Amy E Wagie, Robert R Cima, Elizabeth B Habermann.   

Abstract

BACKGROUND: Stoma reversals (SRs) are commonly performed with potentially significant postoperative complications including surgical site infections (SSIs). Our aim was to determine the incidence and risk factors for SSIs in a large cohort of SR patients.
DESIGN: We reviewed our institutional 2006-2011 American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database for 30-day SSIs in patients undergoing SR. Records were additionally reviewed for 10 non-ACS-NSQIP variables. The primary outcome was SSI after SR. Secondary outcomes were additional 30-day postoperative complications and length-of-stay. Predictors of SSIs were identified using multivariable logistic regression.
RESULTS: From 528 SR patients, 36 patients developed a SSI (6.8 %). Most patients underwent SR for loop ileostomies (76.5 %) after index operations for ulcerative colitis (38.6 %) and colorectal cancer (27.8 %). SSI patients had fewer subcutaneous drains compared to patients with no SSI and had significantly higher rates of smoking, ASA 3-4 classification and laparotomies at SR (p < 0.05). Patients with SSI had increased length-of-stay and 30-day morbidities including sepsis and returns to the operating room (p < 0.05) compared to no-SSI patients. On multivariable analysis, subcutaneous drain placement was suggestive of SSI protection (odds ratio [OR] 0.52, 95 % confidence interval [CI] 0.2-1.1), but only smoking was significantly associated with an increased risk for SSI (OR 2.4, 95 % CI 1.1-5.4).
CONCLUSIONS: Smoking increased the risk of SR SSIs in patients by over twofold, and SR SSIs are associated with additional significant morbidities. Smoking cessation should be an important part of any SSI risk-reduction strategy.

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Year:  2014        PMID: 25217092     DOI: 10.1007/s11605-014-2649-3

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  30 in total

1.  Techniques and complications of ileostomy takedown.

Authors:  P T Phang; J M Hain; J J Perez-Ramirez; R D Madoff; B T Gemlo
Journal:  Am J Surg       Date:  1999-06       Impact factor: 2.565

2.  Abstinence from smoking reduces incisional wound infection: a randomized controlled trial.

Authors:  Lars Tue Sorensen; Tonny Karlsmark; Finn Gottrup
Journal:  Ann Surg       Date:  2003-07       Impact factor: 12.969

3.  Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds.

Authors:  K Reid; P Pockney; T Pollitt; B Draganic; S R Smith
Journal:  Br J Surg       Date:  2010-10       Impact factor: 6.939

Review 4.  The morbidity surrounding reversal of defunctioning ileostomies: a systematic review of 48 studies including 6,107 cases.

Authors:  Andre Chow; Henry S Tilney; Paraskevas Paraskeva; Santhini Jeyarajah; Emmanouil Zacharakis; Sanjay Purkayastha
Journal:  Int J Colorectal Dis       Date:  2009-02-17       Impact factor: 2.571

5.  Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms.

Authors:  D B Allen; J J Maguire; M Mahdavian; C Wicke; L Marcocci; H Scheuenstuhl; M Chang; A X Le; H W Hopf; T K Hunt
Journal:  Arch Surg       Date:  1997-09

6.  Risk factors for surgical site infection after dermatological surgery.

Authors:  Clare F Heal; Petra G Buettner; Herwig Drobetz
Journal:  Int J Dermatol       Date:  2012-07       Impact factor: 2.736

7.  Complications of loop ileostomy closure: a retrospective cohort analysis of 123 patients.

Authors:  S D Mansfield; C Jensen; A S Phair; O T Kelly; S B Kelly
Journal:  World J Surg       Date:  2008-09       Impact factor: 3.352

8.  Outcomes and predictors of incisional surgical site infection in stoma reversal.

Authors:  Mike K Liang; Linda T Li; Andres Avellaneda; Jennifer M Moffett; Stephanie C Hicks; Samir S Awad
Journal:  JAMA Surg       Date:  2013-02       Impact factor: 14.766

9.  Body mass index: surgical site infections and mortality after lower extremity bypass from the National Surgical Quality Improvement Program 2005-2007.

Authors:  Kristina A Giles; Allen D Hamdan; Frank B Pomposelli; Mark C Wyers; Jeffrey J Siracuse; Marc L Schermerhorn
Journal:  Ann Vasc Surg       Date:  2009-07-19       Impact factor: 1.466

Review 10.  Purse-string approximation is superior to primary skin closure following stoma reversal: a systematic review and meta-analysis.

Authors:  D P McCartan; J P Burke; S R Walsh; J C Coffey
Journal:  Tech Coloproctol       Date:  2013-01-25       Impact factor: 3.781

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  12 in total

1.  Meta-analysis and single-center experience on the protective effect of negative suction drains on wound healing after stoma reversal.

Authors:  Philipp-Alexander Neumann; Stefan Reischl; Felix Berg; Carsten Jäger; Helmut Friess; Daniel Reim; Güralp O Ceyhan
Journal:  Int J Colorectal Dis       Date:  2019-12-24       Impact factor: 2.571

2.  Racial disparities in surgical outcomes of patients with Inflammatory Bowel Disease.

Authors:  Samuel R Montgomery; Paris D Butler; Chris J Wirtalla; Karole T Collier; Rebecca L Hoffman; Cary B Aarons; Scott M Damrauer; Rachel R Kelz
Journal:  Am J Surg       Date:  2018-05-12       Impact factor: 2.565

Review 3.  Considerations in Stoma Reversal.

Authors:  Karen L Sherman; Steven D Wexner
Journal:  Clin Colon Rectal Surg       Date:  2017-05-22

4.  Racial Disparities in Readmissions for Patients with Inflammatory Bowel Disease (IBD) After Colorectal Surgery.

Authors:  Drew J Gunnells; Melanie S Morris; Aerin DeRussy; Allison A Gullick; Talha A Malik; Jamie A Cannon; Mary T Hawn; Daniel I Chu
Journal:  J Gastrointest Surg       Date:  2016-01-07       Impact factor: 3.452

Review 5.  Diabetes and Risk of Surgical Site Infection: A Systematic Review and Meta-analysis.

Authors:  Emily T Martin; Keith S Kaye; Caitlin Knott; Huong Nguyen; Maressa Santarossa; Richard Evans; Elizabeth Bertran; Linda Jaber
Journal:  Infect Control Hosp Epidemiol       Date:  2015-10-27       Impact factor: 3.254

6.  Smoking, alcohol consumption, diet and physical activity following stoma formation surgery, stoma-related concerns, and desire for lifestyle advice: a United Kingdom survey.

Authors:  Rebecca J Beeken; Joanne S Haviland; Claire Taylor; Anna Campbell; Abigail Fisher; Chloe Grimmett; Gozde Ozakinci; Sarah Slater; Iseult Wilson; Gill Hubbard
Journal:  BMC Public Health       Date:  2019-05-15       Impact factor: 3.295

Review 7.  Meta-analysis of the impact of postoperative infective complications on oncological outcomes in colorectal cancer surgery.

Authors:  J Lawler; M Choynowski; K Bailey; M Bucholc; A Johnston; M Sugrue
Journal:  BJS Open       Date:  2020-06-11

8.  The technique for less infectious and earlier healing of stoma closure wound: negative pressure wound therapy with instillation and dwelling followed by primary closure.

Authors:  Yoshinori Yane; Jin-Ichi Hida; Yusuke Makutani; Hokuto Ushijima; Yasumasa Yoshioka; Masayoshi Iwamoto; Toshiaki Wada; Koji Daito; Tadao Tokoro; Kazuki Ueda; Junichiro Kawamura
Journal:  BMC Surg       Date:  2021-03-22       Impact factor: 2.102

9.  Negative-pressure wound therapy after stoma reversal in colorectal surgery: a randomized controlled trial.

Authors:  Francesco M Carrano; Annalisa Maroli; Michele Carvello; Caterina Foppa; Matteo Sacchi; Jacopo Crippa; Giuseppe Clerico; Francesca De Lucia; Elisabetta Coppola; Nadav Ben David; Antonino Spinelli
Journal:  BJS Open       Date:  2021-11-09

10.  Effect of closed incision negative pressure wound therapy on incidence rate of surgical site infection after stoma reversal: a pilot study.

Authors:  Maciej Borejsza-Wysocki; Adam Bobkiewicz; Wojciech Francuzik; Lukasz Krokowicz; Dominik Walczak; Jacek Szmeja; Tomasz Banasiewicz
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2021-05-25       Impact factor: 1.195

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