Literature DB >> 25205385

Surgical treatment of thoracolumbar tuberculosis: a retrospective analysis of autogenous grafting versus expandable cages.

Bilgehan Tosun1, Cengiz Erdemir, Omer Yonga, Ozgür Selek.   

Abstract

PURPOSE: There has been no uniform and extensive description of the use of expandable cages in the setting of thoracolumbar tuberculosis. The purpose of the study was to evaluate the results of the expandable cages and compare with autogenous strut grafting in thoracolumbar tuberculosis.
METHODS: From January 2003 to January 2014, a total of 28 patients with thoracolumbar tuberculosis were treated surgically in our medical center. Patients were divided into three groups. 17 patients received anterior-only surgery; consisting of autogenous iliac bone grafting only in 9 (Group 1), grafting with anterior screw-rod system instrumentation after debridement in 8 patients (Group 2). 11 patients underwent anterior surgery including debridement and distraction of the kyphosis by cages after corpectomy following posterior instrumentation (Group 3).The changes in degree of kyphotic deformity, loss of correction, intervertebral height and loss of intervertebral height were evaluated preoperatively, postoperatively and at the final follow-up.
RESULTS: Patients were followed 52 ± 10.7 months (range, 18-120 months). Mean age in the Group 1 was 42 (18-69) years, 62 (19-86) years in the Group 2 and 51 (19-71) years in the Group 3. There was no statistically significant difference (P > 0.05) in the focal kyphosis preoperatively, postoperatively and at the last follow-up between three groups. There were statistically significant differences (P < 0.05) in loss of correction, intervertebral height (preoperative, postoperative and final follow-up) and loss of intervertebral height between three groups. There was a greater loss of correction in Group 1 when compared with Group 2 and Group 3. The difference was statistically significant (p < 0.001). There was no statistically significant difference in the intervertebral height postoperatively and follow-up between Group 1 and Group 2. There was a significant increase in the intervertebral height in Group 3 when compared with Group 1 and Group 2. There was also a significant increase in the intervertebral height in Group 2 when compared with Group 1. There was a greater loss of intervertebral height in Group 1 than in Group 2 and Group 3. The difference was statistically significant (p < 0.001).
CONCLUSIONS: Expandable cages are an acceptable surgical option for the treatment of thoracolumbar tuberculosis. Sagittal alignment is better prevented with the expandable cages than anterior grafting with or without anterior instrumentation. Subsidence of the expandable cages is not uncommon and results in the loss of Cobb angle correction and intervertebral height. However, anterior vertebral column reconstruction by expandable cages provides a very high and effective rate of deformity correction and maintenance.

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Year:  2014        PMID: 25205385     DOI: 10.1007/s00586-014-3565-7

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  27 in total

Review 1.  Instrumented stabilization in spinal tuberculosis.

Authors:  Anil Kumar Jain; Saurabh Jain
Journal:  Int Orthop       Date:  2011-07-01       Impact factor: 3.075

2.  The management of acute thoracolumbar burst fractures with anterior corpectomy and Z-plate fixation.

Authors:  Paul W McDonough; Rick Davis; Clifford Tribus; Thomas A Zdeblick
Journal:  Spine (Phila Pa 1976)       Date:  2004-09-01       Impact factor: 3.468

3.  Threaded fusion cages for lumbar interbody fusions. An economic comparison with 360 degrees fusions.

Authors:  C D Ray
Journal:  Spine (Phila Pa 1976)       Date:  1997-03-15       Impact factor: 3.468

4.  One-stage anterior interbody autografting and instrumentation in primary surgical management of thoracolumbar spinal tuberculosis.

Authors:  Dadi Jin; Dongbin Qu; Jianting Chen; Hao Zhang
Journal:  Eur Spine J       Date:  2003-12-18       Impact factor: 3.134

5.  Vertebral body replacement systems with expandable cages in the treatment of various spinal pathologies: a prospectively followed case series of 60 patients.

Authors:  Mark P Arts; Wilco C Peul
Journal:  Neurosurgery       Date:  2008-09       Impact factor: 4.654

6.  Radiologic stability of titanium mesh cages for anterior spinal reconstruction following thoracolumbar corpectomy.

Authors:  Peter A Robertson; Helen J Rawlinson; Alastair T Hadlow
Journal:  J Spinal Disord Tech       Date:  2004-02

7.  Transthoracic vertebrectomy for metastatic spinal tumors.

Authors:  Z L Gokaslan; J E York; G L Walsh; I E McCutcheon; F F Lang; J B Putnam; D M Wildrick; S G Swisher; D Abi-Said; R Sawaya
Journal:  J Neurosurg       Date:  1998-10       Impact factor: 5.115

8.  Treatment of tuberculous spondylitis with anterior stabilization and titanium cage.

Authors:  Anastasios G Christodoulou; Panagiotis Givissis; Dimitrios Karataglis; Panagiotis D Symeonidis; John Pournaras
Journal:  Clin Orthop Relat Res       Date:  2006-03       Impact factor: 4.176

9.  One-stage anterior debridement, bone grafting and posterior instrumentation vs. single posterior debridement, bone grafting, and instrumentation for the treatment of thoracic and lumbar spinal tuberculosis.

Authors:  Xiyang Wang; Xiaoyang Pang; Ping Wu; Chengke Luo; Xiongjie Shen
Journal:  Eur Spine J       Date:  2013-10-01       Impact factor: 3.134

10.  Progression of kyphosis in tuberculosis of the spine treated by anterior arthrodesis.

Authors:  S Rajasekaran; S Soundarapandian
Journal:  J Bone Joint Surg Am       Date:  1989-10       Impact factor: 5.284

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  13 in total

1.  Anterior versus posterior debridement fusion for single-level dorsal tuberculosis: the role of graft-type and level of fixation on determining the outcome.

Authors:  Yasser M Assaghir; Hesham Hamed Refae; Mohamed Alam-Eddin
Journal:  Eur Spine J       Date:  2016-03-17       Impact factor: 3.134

Review 2.  Comparison of clinical efficacy and safety among three surgical approaches for the treatment of spinal tuberculosis: a meta-analysis.

Authors:  Pinglin Yang; Quanjin Zang; Jian Kang; Haopeng Li; Xijing He
Journal:  Eur Spine J       Date:  2016-03-31       Impact factor: 3.134

3.  Gibbus deformity after non-tuberculosis osteomyelitis.

Authors:  Akop Seksenyan; Darian R Esfahani; Kimberly Hu; Ankit I Mehta
Journal:  J Spine Surg       Date:  2017-12

4.  A comparison of three bone graft struts for interbody fusion using a posterior approach for lower lumbar spinal tuberculosis in adults: a midterm follow-up study.

Authors:  Zhenchao Xu; Xiyang Wang; Zhen Zhang; Dingyu Jiang; Runze Jia; Yilu Zhang
Journal:  BMC Musculoskelet Disord       Date:  2022-06-18       Impact factor: 2.562

5.  [Comparison of short-term effectiveness of structural and non-structural bone graft fusion in treatment of single segment thoracic tuberculosis].

Authors:  Xing Du; Yunsheng Ou; Yong Zhu; Zenghui Zhao; Wei Luo
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2019-04-15

6.  Monosegmental combined anterior posterior instrumentation for the treatment of a severe lumbar tuberculous spondylodiscitis: case report and literature review.

Authors:  Petracchi Matias; Camino Willhuber Gaston; Tripodi Maria; Bassani Julio; Gruenberg Marcelo; Sola Carlos
Journal:  Rev Bras Ortop       Date:  2016-12-29

7.  Comparison between titanium mesh and autogenous iliac bone graft to restore vertebral height through posterior approach for the treatment of thoracic and lumbar spinal tuberculosis.

Authors:  Yongjian Gao; Yunsheng Ou; Qianxing Deng; Bin He; Xing Du; Jianxiao Li
Journal:  PLoS One       Date:  2017-04-13       Impact factor: 3.240

8.  Early results of thoraco lumbar burst fracture treatment using selective corpectomy and rectangular cage reconstruction.

Authors:  Bowei Liang; Guofeng Huang; Luobing Ding; Liangqi Kang; Mo Sha; Zhenqi Ding
Journal:  Indian J Orthop       Date:  2017 Jan-Feb       Impact factor: 1.251

9.  Treatment of Spinal Tuberculosis by Debridement, Interbody Fusion and Internal Fixation via Posterior Approach Only.

Authors:  Ming-xing Tang; Hong-qi Zhang; Yu-xiang Wang; Chao-feng Guo; Jin-yang Liu
Journal:  Orthop Surg       Date:  2016-02       Impact factor: 2.071

10.  Utilization of ring-shaped bone allograft for surgical treatment of adolescent post-tubercular kyphosis: A retrospective study.

Authors:  Xiang Yin; Peng Liu; Yao-Yao Liu; Wei-Li Fan; Bai-Yi Liu; Jian-Hua Zhao
Journal:  Medicine (Baltimore)       Date:  2017-06       Impact factor: 1.817

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