Literature DB >> 25169143

Influence of anatomical variations on lumbar foraminal stenosis pathogenesis.

Sophie Merckaert1, Katarzyna Pierzchala, Gerit Kulik, Constantin Schizas.   

Abstract

INTRODUCTION: Symptomatic foraminal stenosis has been observed in patients with degenerative disc disease, scoliosis, asymmetrical disc degeneration and spondylolisthesis. Nevertheless not all patients with the above pathologies will develop symptomatic foraminal stenosis. We hypothesised that symptomatic patients have anatomical predisposition to foraminal stenosis, namely a larger pedicle height (PH) to vertebral body height (VH) ratio, leaving less room below the pedicle for the exiting nerve root compared to asymptomatic patients. PATIENT SAMPLE: 66 Patients were divided in two groups. The surgical group consisted of 37 patients (average age of 61 years) who presented with severe radicular symptoms resisting to conservative measures and requiring decompression and transforaminal lumbar interbody fusion (TLIF). The control group consisted of 29 patients (average age of 51 years) presenting with low back pain (LBP) but with no radicular symptoms and who were treated conservatively.
METHODS: We measured VH at the level of the posterior wall as well as PH on parasagittal images (CT or MRI) on all lumbar levels (L1 to L5). Statistical analysis was performed using Student's t test.
RESULTS: No difference in PH was found between the two groups for L1 to L4 levels. By contrast, there was a highly statistically significant difference in VH between the two groups from L1 to L4 level. In the surgical group, the VH was smaller (p < 0.001).
CONCLUSIONS: Symptomatic patients with foraminal stenosis have smaller VH leading to lesser space beneath the pedicle and putting the exiting nerve root at risk in cases of spondylolisthesis or disc degeneration.

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Year:  2014        PMID: 25169143     DOI: 10.1007/s00586-014-3524-3

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  14 in total

1.  Morphologic changes in the lumbar intervertebral foramen due to flexion-extension, lateral bending, and axial rotation: an in vitro anatomic and biomechanical study.

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Journal:  Spine (Phila Pa 1976)       Date:  2001-04-15       Impact factor: 3.468

Review 2.  Spine update. Lumbar foraminal stenosis.

Authors:  L G Jenis; H S An
Journal:  Spine (Phila Pa 1976)       Date:  2000-02-01       Impact factor: 3.468

3.  Morphometric analysis of the roots and neural foramina of the lumbar vertebrae.

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Journal:  Surg Neurol       Date:  2006-08

4.  The lumbar roots and pedicles: a morphometric analysis and anatomical features.

Authors:  Fuat Torun; Hakan Tuna; Mustafa Buyukmumcu; Sukru Caglar; Alper Baysefer
Journal:  J Clin Neurosci       Date:  2008-05-16       Impact factor: 1.961

5.  Occult lumbar lateral spinal stenosis in neural foramina subjected to physiologic loading.

Authors:  B H Nowicki; V M Haughton; T A Schmidt; T H Lim; H S An; L H Riley; L Yu; J W Hong
Journal:  AJNR Am J Neuroradiol       Date:  1996-10       Impact factor: 3.825

6.  Qualitative grading of severity of lumbar spinal stenosis based on the morphology of the dural sac on magnetic resonance images.

Authors:  Constantin Schizas; Nicolas Theumann; Alexandre Burn; Rosamond Tansey; Douglas Wardlaw; Francis W Smith; Gerit Kulik
Journal:  Spine (Phila Pa 1976)       Date:  2010-10-01       Impact factor: 3.468

7.  Lumbar foraminal stenosis: critical heights of the intervertebral discs and foramina. A cryomicrotome study in cadavera.

Authors:  T Hasegawa; H S An; V M Haughton; B H Nowicki
Journal:  J Bone Joint Surg Am       Date:  1995-01       Impact factor: 5.284

8.  Prevalence, severity, and impact of foraminal and canal stenosis among adults with degenerative scoliosis.

Authors:  Kai-Ming G Fu; Prashant Rhagavan; Christopher I Shaffrey; Daniel R Chernavvsky; Justin S Smith
Journal:  Neurosurgery       Date:  2011-12       Impact factor: 4.654

9.  Vertebral size in elderly women with osteoporosis. Mechanical implications and relationship to fractures.

Authors:  V Gilsanz; M L Loro; T F Roe; J Sayre; R Gilsanz; E E Schulz
Journal:  J Clin Invest       Date:  1995-05       Impact factor: 14.808

10.  Comparison of metric analysis of spinal structures, exemplarily of the ligamentum flavum, obtained with CT and MRI.

Authors:  T L Schulte; J O Heidenreich; A M Schilling; R Stendel; T A Pietilä; W Hopfenmüller; M Brock; K-J Wolf
Journal:  Eur J Radiol       Date:  2004-12       Impact factor: 3.528

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  3 in total

1.  The Michel Benoist and Robert Mulholland yearly European Spine Journal review: a survey of the "medical" articles in the European Spine Journal, 2015.

Authors:  Michel Benoist
Journal:  Eur Spine J       Date:  2015-11-23       Impact factor: 3.134

2.  A morphometric analysis of all lumbar intervertebral discs and vertebral bodies in degenerative spondylolisthesis.

Authors:  Saher Abu-Leil; Yizhar Floman; Yigal Bronstein; Youssef Masharawi
Journal:  Eur Spine J       Date:  2016-06-27       Impact factor: 3.134

3.  In vivo dynamic changes of dimensions in the lumbar intervertebral foramen.

Authors:  Weiye Zhong; Sean J Driscoll; Tsung-Yuan Tsai; Shaobai Wang; Haiqing Mao; Thomas D Cha; Kirkham B Wood; Guoan Li
Journal:  Spine J       Date:  2015-03-20       Impact factor: 4.166

  3 in total

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