Literature DB >> 25137290

A multimeric MR-optical contrast agent for multimodal imaging.

Victoria S R Harrison1, Christiane E Carney, Keith W Macrenaris, Thomas J Meade.   

Abstract

We describe the design, synthesis and in vitro evaluation of a multimodal and multimeric contrast agent. The agent consists of three macrocyclic Gd(III) chelates conjugated to a fluorophore and possesses high relaxivity, water solubility, and is nontoxic. The modular synthesis is amenable for the incorporation of a variety of fluorophores to generate molecular constructs for a number of applications.

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Year:  2014        PMID： 25137290      PMCID： PMC4344311          DOI： 10.1039/c4cc05651e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  24 in total

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  7 in total

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