Literature DB >> 25126511

Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel.

Matthias R Steinwachs1, Bernhard Waibl1, Marcus Mumme1.   

Abstract

Bone marrow stimulation techniques for the treatment of articular cartilage defects such as microfracture so far have solely reproduced mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm follow-up. A recent study has shown an improvement in repair tissue quality by enhancing microfracture with a chitosan-based biomaterial (BST-CarGel; Piramal, Laval, Quebec, Canada). BST-CarGel so far has only been applied by arthrotomy, which might lead to increased scar tissue formation and thus compromise recovery time and clinical outcome. We describe a surgical technique for an arthroscopic treatment of cartilage defects of the knee with microfracture in combination with BST-CarGel to benefit from improved repair tissue quality and to reduce arthrotomy-related morbidity.

Entities:  

Year:  2014        PMID: 25126511      PMCID: PMC4129984          DOI: 10.1016/j.eats.2014.02.011

Source DB:  PubMed          Journal:  Arthrosc Tech        ISSN: 2212-6287


  4 in total

1.  Novel scaffold-based BST-CarGel treatment results in superior cartilage repair compared with microfracture in a randomized controlled trial.

Authors:  William D Stanish; Robert McCormack; Francisco Forriol; Nicholas Mohtadi; Stéphane Pelet; Jacques Desnoyers; Alberto Restrepo; Matthew S Shive
Journal:  J Bone Joint Surg Am       Date:  2013-09-18       Impact factor: 5.284

2.  Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture.

Authors:  Daniel B F Saris; Johan Vanlauwe; Jan Victor; Karl Fredrik Almqvist; Rene Verdonk; Johan Bellemans; Frank P Luyten
Journal:  Am J Sports Med       Date:  2009-10-21       Impact factor: 6.202

3.  Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation.

Authors:  M Brittberg; A Lindahl; A Nilsson; C Ohlsson; O Isaksson; L Peterson
Journal:  N Engl J Med       Date:  1994-10-06       Impact factor: 91.245

Review 4.  Clinical efficacy of the microfracture technique for articular cartilage repair in the knee: an evidence-based systematic analysis.

Authors:  Kai Mithoefer; Timothy McAdams; Riley J Williams; Peter C Kreuz; Bert R Mandelbaum
Journal:  Am J Sports Med       Date:  2009-02-26       Impact factor: 6.202

  4 in total
  11 in total

1.  Reconstruction of Focal Femoral Head Cartilage Defects With a Chitin-Based Scaffold.

Authors:  Ahmed Al-Qarni; Matthew R Lewington; Ivan H Wong
Journal:  Arthrosc Tech       Date:  2016-03-14

2.  Labral Gracilis Tendon Allograft Reconstruction and Cartilage Regeneration Scaffold for an Uncontained Acetabular Cartilage Defect of the Hip.

Authors:  Laurel E MacInnis; Ahmed Al Hussain; Catherine Coady; Ivan H Wong
Journal:  Arthrosc Tech       Date:  2017-05-22

Review 3.  The current state of scaffolds for musculoskeletal regenerative applications.

Authors:  Benjamin D Smith; Daniel A Grande
Journal:  Nat Rev Rheumatol       Date:  2015-03-17       Impact factor: 20.543

Review 4.  Understanding Magnetic Resonance Imaging of Knee Cartilage Repair: A Focus on Clinical Relevance.

Authors:  Daichi Hayashi; Xinning Li; Akira M Murakami; Frank W Roemer; Siegfried Trattnig; Ali Guermazi
Journal:  Cartilage       Date:  2017-06-05       Impact factor: 4.634

5.  Fabrication and development of artificial osteochondral constructs based on cancellous bone/hydrogel hybrid scaffold.

Authors:  Kedong Song; Liying Li; Xinyu Yan; Yu Zhang; Ruipeng Li; Yiwei Wang; Ling Wang; Hong Wang; Tianqing Liu
Journal:  J Mater Sci Mater Med       Date:  2016-05-14       Impact factor: 3.896

Review 6.  Thermosensitive Chitosan-β-Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications.

Authors:  Pouria Rahmanian-Devin; Vafa Baradaran Rahimi; Vahid Reza Askari
Journal:  Adv Pharmacol Pharm Sci       Date:  2021-05-05

7.  Treatment of Patellofemoral Chondral Lesions Using Microfractures Associated with a Chitosan Scaffold: Mid-Term Clinical and Radiological Results.

Authors:  Rafael Calvo; David Figueroa; Francisco Figueroa; Jose Bravo; Martin Contreras; Nicolas Zilleruelo
Journal:  Cartilage       Date:  2021-04-27       Impact factor: 3.117

8.  Peripheral blood derived mononuclear cells enhance the migration and chondrogenic differentiation of multipotent mesenchymal stromal cells.

Authors:  Niina Hopper; John Wardale; Daniel Howard; Roger Brooks; Neil Rushton; Frances Henson
Journal:  Stem Cells Int       Date:  2015-01-12       Impact factor: 5.443

9.  Arthroscopic Treatment of Hip Chondral Defects With Bone Marrow Stimulation and BST-CarGel.

Authors:  Marc Tey; Jesús Mas; Xavier Pelfort; Joan Carles Monllau
Journal:  Arthrosc Tech       Date:  2015-01-19

10.  Bi-layered Composite Scaffold for Repair of the Osteochondral Defects.

Authors:  Dongdong Xu; Gu Cheng; Jinhong Dai; Zhi Li
Journal:  Adv Wound Care (New Rochelle)       Date:  2020-12-18       Impact factor: 4.947

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