Literature DB >> 27354944

Reconstruction of Focal Femoral Head Cartilage Defects With a Chitin-Based Scaffold.

Ahmed Al-Qarni1, Matthew R Lewington1, Ivan H Wong1.   

Abstract

It is well known that articular cartilage defects have little capability to heal. For grade III or IV cartilage defects, surgical intervention may be required for symptomatic patients. Microfracture is a commonly used surgical technique to address these injuries. However, microfracture has drawbacks, which include the risk of ossification of the newly formed tissue, as well as the imperfect and fragile nature of the fibrous cartilage. Given the challenges associated with microfracture, BST-CarGel (Piramal Healthcare, Laval, Quebec, Canada) has been developed to stabilize and support the nascent clot. This chitin-based polymer is mixed with the patient's own blood and inserted onto the microfractured defect. The polymer allows normal clot formation and provides a matrix to strengthen the clot, prevent retraction, and increase its adhesiveness to the natural tissue. We present, with a video example, a detailed arthroscopic technique for using BST-CarGel to fill a focal femoral head cartilage defect.

Entities:  

Year:  2016        PMID: 27354944      PMCID: PMC4912569          DOI: 10.1016/j.eats.2015.12.005

Source DB:  PubMed          Journal:  Arthrosc Tech        ISSN: 2212-6287


  17 in total

1.  Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes.

Authors:  J Richard Steadman; William G Rodkey; Karen K Briggs
Journal:  J Knee Surg       Date:  2002       Impact factor: 2.757

Review 2.  Microfracture of the hip in athletes.

Authors:  Kevin Crawford; Marc J Philippon; Jon K Sekiya; William G Rodkey; J Richard Steadman
Journal:  Clin Sports Med       Date:  2006-04       Impact factor: 2.182

Review 3.  Pathomechanics and classification of cartilage lesions, facilitation of repair.

Authors:  J M Walker
Journal:  J Orthop Sports Phys Ther       Date:  1998-10       Impact factor: 4.751

4.  Operative treatment of chondral defects in the hip joint: a systematic review.

Authors:  Mark A Jordan; Geoffrey S Van Thiel; Jaskarndip Chahal; Shane J Nho
Journal:  Curr Rev Musculoskelet Med       Date:  2012-09

5.  Microfractures in coxarthrosis.

Authors:  B Koszyca; N L Fazzalari; B Vernon-Roberts
Journal:  Acta Orthop Scand       Date:  1990-08

6.  A matched-pair controlled study of microfracture of the hip with average 2-year follow-up: do full-thickness chondral defects portend an inferior prognosis in hip arthroscopy?

Authors:  Benjamin G Domb; John M Redmond; Kevin F Dunne; Christine E Stake; Asheesh Gupta
Journal:  Arthroscopy       Date:  2014-12-10       Impact factor: 4.772

7.  Novel scaffold-based BST-CarGel treatment results in superior cartilage repair compared with microfracture in a randomized controlled trial.

Authors:  William D Stanish; Robert McCormack; Francisco Forriol; Nicholas Mohtadi; Stéphane Pelet; Jacques Desnoyers; Alberto Restrepo; Matthew S Shive
Journal:  J Bone Joint Surg Am       Date:  2013-09-18       Impact factor: 5.284

Review 8.  Clinical efficacy of the microfracture technique for articular cartilage repair in the knee: an evidence-based systematic analysis.

Authors:  Kai Mithoefer; Timothy McAdams; Riley J Williams; Peter C Kreuz; Bert R Mandelbaum
Journal:  Am J Sports Med       Date:  2009-02-26       Impact factor: 6.202

9.  Arthroscopic Treatment of Hip Chondral Defects With Bone Marrow Stimulation and BST-CarGel.

Authors:  Marc Tey; Jesús Mas; Xavier Pelfort; Joan Carles Monllau
Journal:  Arthrosc Tech       Date:  2015-01-19

10.  Microfracture for acetabular chondral defects in patients with femoroacetabular impingement: results at second-look arthroscopic surgery.

Authors:  Shanmugam Karthikeyan; Sally Roberts; Damian Griffin
Journal:  Am J Sports Med       Date:  2012-11-07       Impact factor: 6.202

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  4 in total

1.  Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel®.

Authors:  Mahmoud Tahoun; Tamer Aly Shehata; Inmaculada Ormazabal; Jesús Mas; Javier Sanz; Marc Tey Pons
Journal:  SICOT J       Date:  2017-08-07

Review 2.  Chondral lesions in the hip: a review of relevant anatomy, imaging and treatment modalities.

Authors:  Alison A Dallich; Ehud Rath; Ran Atzmon; Joshua R Radparvar; Andrea Fontana; Zachary Sharfman; Eyal Amar
Journal:  J Hip Preserv Surg       Date:  2019-04-16

3.  Arthroscopic Approach to Preservation of the Hip with Avascular Necrosis.

Authors:  Johnny Rayes; Ivan Wong
Journal:  Arthrosc Tech       Date:  2021-09-08

Review 4.  Osteochondral tissue engineering: Perspectives for clinical application and preclinical development.

Authors:  Chengchong Ai; Yee Han Dave Lee; Xuan Hao Tan; Si Heng Sharon Tan; James Hoi Po Hui; James Cho-Hong Goh
Journal:  J Orthop Translat       Date:  2021-10-11       Impact factor: 5.191

  4 in total

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