OBJECTIVES: To determine the prevalence of hepatitis B virus (HVB) infection and seroprotection in indigenous children living in three draining basins of the Peruvian Amazon. MATERIALS AND METHODS: A cross sectional study was conducted in three draining basins (Pastaza, Morona and Lower Urubamba rivers), home to six indigenous populations: shapra, candoshi, machiguenga, yine, ashaninka and nanti. Children under 5 years were included. A survey and review of the vaccination card was applied, and a serum sample was processed with ELISA for HBsAg, total anti-HBc and anti-HBs was obtained, defining "seroprotected children" if they were reactive to anti-HBs and non-reactive to anti-HBc. RESULTS: A total of 742 children under 5 years old residents in six indigenous communities were included in the study. 380 (51.2%) were male and 169 (22.9%) one year old or younger. Regarding recorded HVB vaccination on the card, only 434 (58.5%) had received three doses; 208 (38.8%) received the first dose within 24 hours. No cases were detected with HBsAg. 88.8% of children had seroconverted, varying between 67-100% across the populations. CONCLUSIONS: No cases of chronic HBV infection were detected. The vaccination coverage by card revision is low, contrasting with high seroconversion rates.
OBJECTIVES: To determine the prevalence of hepatitis B virus (HVB) infection and seroprotection in indigenous children living in three draining basins of the Peruvian Amazon. MATERIALS AND METHODS: A cross sectional study was conducted in three draining basins (Pastaza, Morona and Lower Urubamba rivers), home to six indigenous populations: shapra, candoshi, machiguenga, yine, ashaninka and nanti. Children under 5 years were included. A survey and review of the vaccination card was applied, and a serum sample was processed with ELISA for HBsAg, total anti-HBc and anti-HBs was obtained, defining "seroprotected children" if they were reactive to anti-HBs and non-reactive to anti-HBc. RESULTS: A total of 742 children under 5 years old residents in six indigenous communities were included in the study. 380 (51.2%) were male and 169 (22.9%) one year old or younger. Regarding recorded HVB vaccination on the card, only 434 (58.5%) had received three doses; 208 (38.8%) received the first dose within 24 hours. No cases were detected with HBsAg. 88.8% of children had seroconverted, varying between 67-100% across the populations. CONCLUSIONS: No cases of chronic HBV infection were detected. The vaccination coverage by card revision is low, contrasting with high seroconversion rates.
Authors: Nancy K Russell; Kevin Nazar; Sandra Del Pino; Monica Alonso Gonzalez; Ximena P Díaz Bermúdez; Giovanni Ravasi Journal: Rev Panam Salud Publica Date: 2019-01-04
Authors: Diana María Castro-Arroyave; Jaime Alberto Martínez-Gallego; Melissa Montoya-Guzmán; Gustavo Silva; Carlos Alberto Rojas Arbeláez Journal: Rev Panam Salud Publica Date: 2022-03-23
Authors: Cesar Cabezas; Omar Trujillo; Ángel Gonzales-Vivanco; Carlos Manuel Benites Villafane; Johanna Balbuena; Alfredo Oswaldo Borda-Olivas; Magna Aurora Suarez-Jara; Flor de María Peceros; Max Carlos Ramírez-Soto Journal: PLoS One Date: 2020-06-15 Impact factor: 3.240
Authors: Bárbara Badanta; Giancarlo Lucchetti; Sergio Barrientos-Trigo; Elena Fernández-García; Lorena Tarriño-Concejero; Juan Vega-Escaño; Rocío de Diego-Cordero Journal: Int J Environ Res Public Health Date: 2020-10-22 Impact factor: 3.390