Literature DB >> 25122857

Evaluation of the nanosphere Verigene BC-GN assay for direct identification of gram-negative bacilli and antibiotic resistance markers from positive blood cultures and potential impact for more-rapid antibiotic interventions.

Joseph T Hill1, Kim-Dung T Tran1, Karen L Barton2, Matthew J Labreche2, Susan E Sharp3.   

Abstract

The Verigene BC-GN assay correctly identified all 51 Gram-negative bacilli (GNB) from positive blood cultures and all 14 carbapenemase enzymes tested. The assay gave organism identification (ID) results an average of 24 h faster compared to conventional identifications. Medical management could have been modified for 31.8% of patients an average 33 h sooner. In conclusion, the BC-GN assay is a very accurate, rapid assay which would allow for more-immediate medical management decisions in patients with bacteremia from GNB.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25122857      PMCID： PMC4187775          DOI： 10.1128/JCM.01537-14

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  14 in total

1.  Clinical impact of a real-time PCR assay for rapid identification of staphylococcal bacteremia.

Authors:  Abigail M Frye; Catherine A Baker; D Leif Rustvold; Kim A Heath; Jessica Hunt; James E Leggett; Margret Oethinger
Journal:  J Clin Microbiol       Date:  2011-11-09       Impact factor: 5.948

2.  An antimicrobial stewardship program's impact with rapid polymerase chain reaction methicillin-resistant Staphylococcus aureus/S. aureus blood culture test in patients with S. aureus bacteremia.

Authors:  Karri A Bauer; Jessica E West; Joan-Miquel Balada-Llasat; Preeti Pancholi; Kurt B Stevenson; Debra A Goff
Journal:  Clin Infect Dis       Date:  2010-11-01       Impact factor: 9.079

3.  Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain.

Authors:  Louis Valiquette; Benoit Cossette; Marie-Pierre Garant; Hassan Diab; Jacques Pépin
Journal:  Clin Infect Dis       Date:  2007-09-01       Impact factor: 9.079

4.  Potential impact of a microarray-based nucleic acid assay for rapid detection of Gram-negative bacteria and resistance markers in positive blood cultures.

Authors:  Nicasio Mancini; Laura Infurnari; Nadia Ghidoli; Grazia Valzano; Nicola Clementi; Roberto Burioni; Massimo Clementi
Journal:  J Clin Microbiol       Date:  2014-01-29       Impact factor: 5.948

Review 5.  Bacteremias: a leading cause of death.

Authors:  Gonzalo M L Bearman; Richard P Wenzel
Journal:  Arch Med Res       Date:  2005 Nov-Dec       Impact factor: 2.235

6.  Hospital-wide restriction of clindamycin: effect on the incidence of Clostridium difficile-associated diarrhea and cost.

Authors:  M W Climo; D S Israel; E S Wong; D Williams; P Coudron; S M Markowitz
Journal:  Ann Intern Med       Date:  1998-06-15       Impact factor: 25.391

7.  Gram-negative bloodstream infections.

Authors:  Martin E Stryjewski; Helen W Boucher
Journal:  Int J Antimicrob Agents       Date:  2009       Impact factor: 5.283

Review 8.  Optimizing antimicrobial therapy in sepsis and septic shock.

Authors:  Anand Kumar
Journal:  Crit Care Clin       Date:  2009-10       Impact factor: 3.598

9.  Stewardship approach for optimizing antimicrobial therapy through use of a rapid microarray assay on blood cultures positive for Enterococcus species.

Authors:  Aaron Sango; Yvette S McCarter; Donald Johnson; Jason Ferreira; Nilmarie Guzman; Christopher A Jankowski
Journal:  J Clin Microbiol       Date:  2013-09-25       Impact factor: 5.948

10.  Evaluation of an automated rapid diagnostic assay for detection of Gram-negative bacteria and their drug-resistance genes in positive blood cultures.

Authors:  Masayoshi Tojo; Takahiro Fujita; Yusuke Ainoda; Maki Nagamatsu; Kayoko Hayakawa; Kazuhisa Mezaki; Aki Sakurai; Yoshinori Masui; Hirohisa Yazaki; Hiroshi Takahashi; Tohru Miyoshi-Akiyama; Kyoichi Totsuka; Teruo Kirikae; Norio Ohmagari
Journal:  PLoS One       Date:  2014-04-04       Impact factor: 3.240
View more
  30 in total

1.  Preliminary Evaluation of the Research-Use-Only (RUO) iCubate iC-GPC Assay for Identification of Select Gram-Positive Bacteria and Their Resistance Determinants in Blood Culture Broths.

Authors:  Blake W Buchan; Garrett C Reymann; Paul A Granato; Brenda R Alkins; Patricia Jim; Stephen Young
Journal:  J Clin Microbiol       Date:  2015-10-14       Impact factor: 5.948

2.  A Stewardship Approach To Optimize Antimicrobial Therapy through Use of a Rapid Microarray Assay on Blood Cultures Positive for Gram-Negative Bacteria.

Authors:  Conner Sothoron; Jason Ferreira; Nilmarie Guzman; Petra Aldridge; Yvette S McCarter; Christopher A Jankowski
Journal:  J Clin Microbiol       Date:  2015-08-19       Impact factor: 5.948

3.  Rapid testing using the Verigene Gram-negative blood culture nucleic acid test in combination with antimicrobial stewardship intervention against Gram-negative bacteremia.

Authors:  Jacqueline T Bork; Surbhi Leekha; Emily L Heil; LiCheng Zhao; Rilwan Badamas; J Kristie Johnson
Journal:  Antimicrob Agents Chemother       Date:  2014-12-29       Impact factor: 5.191

4.  Evaluation of the Accelerate Pheno System for Fast Identification and Antimicrobial Susceptibility Testing from Positive Blood Cultures in Bloodstream Infections Caused by Gram-Negative Pathogens.

Authors:  Matthias Marschal; Johanna Bachmaier; Ingo Autenrieth; Philipp Oberhettinger; Matthias Willmann; Silke Peter
Journal:  J Clin Microbiol       Date:  2017-04-26       Impact factor: 5.948

5.  Parallel Evaluation of the MALDI Sepsityper and Verigene BC-GN Assays for Rapid Identification of Gram-Negative Bacilli from Positive Blood Cultures.

Authors:  Miguel A Arroyo; Gerald A Denys
Journal:  J Clin Microbiol       Date:  2017-06-21       Impact factor: 5.948

6.  Identification of Gram-Negative Bacteria and Genetic Resistance Determinants from Positive Blood Culture Broths by Use of the Verigene Gram-Negative Blood Culture Multiplex Microarray-Based Molecular Assay.

Authors:  Nathan A Ledeboer; Bert K Lopansri; Neelam Dhiman; Robert Cavagnolo; Karen C Carroll; Paul Granato; Richard Thomson; Susan M Butler-Wu; Heather Berger; Linoj Samuel; Preeti Pancholi; Lettie Swyers; Glen T Hansen; Nam K Tran; Christopher R Polage; Kenneth S Thomson; Nancy D Hanson; Richard Winegar; Blake W Buchan
Journal:  J Clin Microbiol       Date:  2015-05-20       Impact factor: 5.948

Review 7.  Carbapenem-resistant Enterobacteriaceae in special populations: Solid organ transplant recipients, stem cell transplant recipients, and patients with hematologic malignancies.

Authors:  Stephanie M Pouch; Michael J Satlin
Journal:  Virulence       Date:  2016-07-28       Impact factor: 5.882

8.  Impact of antimicrobial stewardship and rapid microarray testing on patients with Gram-negative bacteremia.

Authors:  K R Rivard; V Athans; S W Lam; S M Gordon; G W Procop; S S Richter; E Neuner
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-05-23       Impact factor: 3.267

9.  Clinical Impact of Laboratory Implementation of Verigene BC-GN Microarray-Based Assay for Detection of Gram-Negative Bacteria in Positive Blood Cultures.

Authors:  Tamar Walker; Sandrea Dumadag; Christine Jiyoun Lee; Seung Heon Lee; Jeffrey M Bender; Jennifer Cupo Abbott; Rosemary C She
Journal:  J Clin Microbiol       Date:  2016-04-20       Impact factor: 5.948

10.  Rapid Detection of Bacteria from Blood with Surface-Enhanced Raman Spectroscopy.

Authors:  Anna K Boardman; Winnie S Wong; W Ranjith Premasiri; Lawrence D Ziegler; Jean C Lee; Milos Miljkovic; Catherine M Klapperich; Andre Sharon; Alexis F Sauer-Budge
Journal:  Anal Chem       Date:  2016-08-02       Impact factor: 6.986
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.