| Literature DB >> 25120391 |
Ana Maria Segura1, Lamia Dris1, Edward K Massin1, Fred J Clubb1, L Maximilian Buja1, O H Frazier1, Heinrich Taegtmeyer1.
Abstract
Mechanical cardiac unloading with use of a left ventricular assist device (LVAD) is associated with substantial improvements in left ventricular function and enables subsequent LVAD explantation in some patients. We describe the case of a 35-year-old man with dilated nonischemic cardiomyopathy who was supported with an LVAD for 9 months. After the device was removed, he led a normal life for 13 years and 4 months. However, at 49 years of age, he presented with new signs and symptoms of heart failure, necessitating implantation of a 2nd LVAD. Afterwards, he has remained asymptomatic. This case is unique in that the patient lived a normal life for longer than a decade before renewed left ventricular decompensation necessitated repeat LVAD therapy. Histologic examination revealed few changes between the first device's removal in 1999 and the 2nd device's implantation in 2012.Entities:
Keywords: Cardiomyopathy, dilated/physiopathology/therapy; device removal; heart failure/physiopathology/therapy; heart-assist devices; myocytes, cardiac/pathology; recovery of function/physiology; recurrence; time factors; treatment outcome; ventricular dysfunction, left/physiology; ventricular remodeling
Mesh：
Year: 2014 PMID： 25120391 PMCID： PMC4120501 DOI： 10.14503/THIJ-13-4029
Source DB: PubMed Journal: Tex Heart Inst J ISSN： 0730-2347