Literature DB >> 25096019

Cyclometalated Ir(III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy.

Rui-Rong Ye1, Cai-Ping Tan, Liang He, Mu-He Chen, Liang-Nian Ji, Zong-Wan Mao.   

Abstract

The successful design and anticancer mechanistic studies of a series of cyclometalated Ir(III) complexes with histone deacetylase inhibitory and photodynamic therapy (PDT) activities are reported.

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Year:  2014        PMID： 25096019     DOI： 10.1039/c4cc05215c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Histone deacetylase 3 inhibits new tumor suppressor gene DTWD1 in gastric cancer.

Authors:  Yanning Ma; Yongfang Yue; Min Pan; Jie Sun; Jue Chu; Xiaoying Lin; Wenxia Xu; Lifeng Feng; Yan Chen; Dingwei Chen; Vivian Y Shin; Xian Wang; Hongchuan Jin
Journal:  Am J Cancer Res       Date:  2015-01-15       Impact factor: 6.166

Review 2.  The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Authors:  Leli Zeng; Pranav Gupta; Yanglu Chen; Enju Wang; Liangnian Ji; Hui Chao; Zhe-Sheng Chen
Journal:  Chem Soc Rev       Date:  2017-10-02       Impact factor: 54.564

3.  Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A.

Authors:  Andrea Halaburková; Rastislav Jendželovský; Ján Kovaľ; Zdenko Herceg; Peter Fedoročko; Akram Ghantous
Journal:  Clin Epigenetics       Date:  2017-06-08       Impact factor: 6.551

4.  Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium(iii) complexes.

Authors:  Jian-Jun Cao; Cai-Ping Tan; Mu-He Chen; Na Wu; De-Yang Yao; Xing-Guo Liu; Liang-Nian Ji; Zong-Wan Mao
Journal:  Chem Sci       Date:  2016-08-22       Impact factor: 9.825

5.  Anticancer Ruthenium Complexes with HDAC Isoform Selectivity.

Authors:  Jasmine M Cross; Tim R Blower; Alexander D H Kingdon; Robert Pal; David M Picton; James W Walton
Journal:  Molecules       Date:  2020-05-21       Impact factor: 4.411

6.  Cyclometalated iridium-BODIPY ratiometric O2 sensors.

Authors:  Ku Sun Choung; Karen Marroquin; Thomas S Teets
Journal:  Chem Sci       Date:  2019-04-15       Impact factor: 9.825

7.  Ester-Modified Cyclometalated Iridium(III) Complexes as Mitochondria-Targeting Anticancer Agents.

Authors:  Fang-Xin Wang; Mu-He Chen; Xiao-Ying Hu; Rui-Rong Ye; Cai-Ping Tan; Liang-Nian Ji; Zong-Wan Mao
Journal:  Sci Rep       Date:  2016-12-13       Impact factor: 4.379

8.  Metal Complexes for Two-Photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two-Photon Photosensitization of Cancer Cells under Near-IR Light.

Authors:  Luke K McKenzie; Igor V Sazanovich; Elizabeth Baggaley; Mickaële Bonneau; Véronique Guerchais; J A Gareth Williams; Julia A Weinstein; Helen E Bryant
Journal:  Chemistry       Date:  2016-11-02       Impact factor: 5.236

9.  Cyclometalated iridium(iii) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents.

Authors:  Liang He; Yi Li; Cai-Ping Tan; Rui-Rong Ye; Mu-He Chen; Jian-Jun Cao; Liang-Nian Ji; Zong-Wan Mao
Journal:  Chem Sci       Date:  2015-07-22       Impact factor: 9.825

10.  Pyridazine-bridged cationic diiridium complexes as potential dual-mode bioimaging probes.

Authors:  Ruth E Daniels; Luke K McKenzie; Jonathan R Shewring; Julia A Weinstein; Valery N Kozhevnikov; Helen E Bryant
Journal:  RSC Adv       Date:  2018-03-06       Impact factor: 3.361
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