Literature DB >> 25089180

BioBenchmark Toyama 2012: an evaluation of the performance of triple stores on biological data.

Hongyan Wu1, Toyofumi Fujiwara2, Yasunori Yamamoto1, Jerven Bolleman3, Atsuko Yamaguchi1.   

Abstract

BACKGROUND: Biological databases vary enormously in size and data complexity, from small databases that contain a few million Resource Description Framework (RDF) triples to large databases that contain billions of triples. In this paper, we evaluate whether RDF native stores can be used to meet the needs of a biological database provider. Prior evaluations have used synthetic data with a limited database size. For example, the largest BSBM benchmark uses 1 billion synthetic e-commerce knowledge RDF triples on a single node. However, real world biological data differs from the simple synthetic data much. It is difficult to determine whether the synthetic e-commerce data is efficient enough to represent biological databases. Therefore, for this evaluation, we used five real data sets from biological databases.
RESULTS: We evaluated five triple stores, 4store, Bigdata, Mulgara, Virtuoso, and OWLIM-SE, with five biological data sets, Cell Cycle Ontology, Allie, PDBj, UniProt, and DDBJ, ranging in size from approximately 10 million to 8 billion triples. For each database, we loaded all the data into our single node and prepared the database for use in a classical data warehouse scenario. Then, we ran a series of SPARQL queries against each endpoint and recorded the execution time and the accuracy of the query response.
CONCLUSIONS: Our paper shows that with appropriate configuration Virtuoso and OWLIM-SE can satisfy the basic requirements to load and query biological data less than 8 billion or so on a single node, for the simultaneous access of 64 clients. OWLIM-SE performs best for databases with approximately 11 million triples; For data sets that contain 94 million and 590 million triples, OWLIM-SE and Virtuoso perform best. They do not show overwhelming advantage over each other; For data over 4 billion Virtuoso works best. 4store performs well on small data sets with limited features when the number of triples is less than 100 million, and our test shows its scalability is poor; Bigdata demonstrates average performance and is a good open source triple store for middle-sized (500 million or so) data set; Mulgara shows a little of fragility.

Entities:  

Year:  2014        PMID: 25089180      PMCID: PMC4118313          DOI: 10.1186/2041-1480-5-32

Source DB:  PubMed          Journal:  J Biomed Semantics


  19 in total

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Review 3.  Semantic Web meets Integrative Biology: a survey.

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Journal:  Brief Bioinform       Date:  2012-04-06       Impact factor: 11.622

Review 4.  Biological knowledge management: the emerging role of the Semantic Web technologies.

Authors:  Erick Antezana; Martin Kuiper; Vladimir Mironov
Journal:  Brief Bioinform       Date:  2009-05-19       Impact factor: 11.622

5.  Semantic web for integrated network analysis in biomedicine.

Authors:  Huajun Chen; Li Ding; Zhaohui Wu; Tong Yu; Lavanya Dhanapalan; Jake Y Chen
Journal:  Brief Bioinform       Date:  2009-03       Impact factor: 11.622

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Journal:  Nucleic Acids Res       Date:  1997-01-01       Impact factor: 16.971

7.  Gauging triple stores with actual biological data.

Authors:  Vladimir Mironov; Nirmala Seethappan; Ward Blondé; Erick Antezana; Andrea Splendiani; Martin Kuiper
Journal:  BMC Bioinformatics       Date:  2012-01-25       Impact factor: 3.169

8.  The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies.

Authors:  Toshiaki Katayama; Mark D Wilkinson; Gos Micklem; Shuichi Kawashima; Atsuko Yamaguchi; Mitsuteru Nakao; Yasunori Yamamoto; Shinobu Okamoto; Kenta Oouchida; Hong-Woo Chun; Jan Aerts; Hammad Afzal; Erick Antezana; Kazuharu Arakawa; Bruno Aranda; Francois Belleau; Jerven Bolleman; Raoul Jp Bonnal; Brad Chapman; Peter Ja Cock; Tore Eriksson; Paul Mk Gordon; Naohisa Goto; Kazuhiro Hayashi; Heiko Horn; Ryosuke Ishiwata; Eli Kaminuma; Arek Kasprzyk; Hideya Kawaji; Nobuhiro Kido; Young Joo Kim; Akira R Kinjo; Fumikazu Konishi; Kyung-Hoon Kwon; Alberto Labarga; Anna-Lena Lamprecht; Yu Lin; Pierre Lindenbaum; Luke McCarthy; Hideyuki Morita; Katsuhiko Murakami; Koji Nagao; Kozo Nishida; Kunihiro Nishimura; Tatsuya Nishizawa; Soichi Ogishima; Keiichiro Ono; Kazuki Oshita; Keun-Joon Park; Pjotr Prins; Taro L Saito; Matthias Samwald; Venkata P Satagopam; Yasumasa Shigemoto; Richard Smith; Andrea Splendiani; Hideaki Sugawara; James Taylor; Rutger A Vos; David Withers; Chisato Yamasaki; Christian M Zmasek; Shoko Kawamoto; Kosaku Okubo; Kiyoshi Asai; Toshihisa Takagi
Journal:  J Biomed Semantics       Date:  2013-02-11

9.  The DNA Data Bank of Japan launches a new resource, the DDBJ Omics Archive of functional genomics experiments.

Authors:  Yuichi Kodama; Jun Mashima; Eli Kaminuma; Takashi Gojobori; Osamu Ogasawara; Toshihisa Takagi; Kousaku Okubo; Yasukazu Nakamura
Journal:  Nucleic Acids Res       Date:  2011-11-22       Impact factor: 16.971

10.  BioMagResBank.

Authors:  Eldon L Ulrich; Hideo Akutsu; Jurgen F Doreleijers; Yoko Harano; Yannis E Ioannidis; Jundong Lin; Miron Livny; Steve Mading; Dimitri Maziuk; Zachary Miller; Eiichi Nakatani; Christopher F Schulte; David E Tolmie; R Kent Wenger; Hongyang Yao; John L Markley
Journal:  Nucleic Acids Res       Date:  2007-11-04       Impact factor: 16.971

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  2 in total

1.  BioFed: federated query processing over life sciences linked open data.

Authors:  Ali Hasnain; Qaiser Mehmood; Syeda Sana E Zainab; Muhammad Saleem; Claude Warren; Durre Zehra; Stefan Decker; Dietrich Rebholz-Schuhmann
Journal:  J Biomed Semantics       Date:  2017-03-15

2.  Publishing FAIR Data: An Exemplar Methodology Utilizing PHI-Base.

Authors:  Alejandro Rodríguez-Iglesias; Alejandro Rodríguez-González; Alistair G Irvine; Ane Sesma; Martin Urban; Kim E Hammond-Kosack; Mark D Wilkinson
Journal:  Front Plant Sci       Date:  2016-05-12       Impact factor: 5.753

  2 in total

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