Literature DB >> 25081966

Posterior fixation without debridement for vertebral body osteomyelitis and discitis.

Ahmed S Mohamed1, Jung Yoo, Robert Hart, Brian T Ragel, Jayme Hiratzka, D Kojo Hamilton, Penelope D Barnes, Alexander C Ching.   

Abstract

OBJECT: The authors evaluated the efficacy of posterior instrumentation for the management of spontaneous spinal infections. Standard surgical management of spontaneous spinal infection is based on debridement of the infected tissue. However, this can be very challenging as most of these patients are medically debilitated and the surgical debridement requires a more aggressive approach to the spine either anteriorly or via an expanded posterior approach. The authors present their results using an alternative treatment method of posterior-only neuro-decompression and stabilization without formal debridement of anterior tissue for treating spontaneous spinal infection.
METHODS: Fifteen consecutive patients were treated surgically by 2 of the authors. All patients had osteomyelitis and discitis and were treated postoperatively with intravenous antibiotics for at least 6 weeks. The indications for surgery were failed medical management, progressive deformity with ongoing persistent spinal infection, or neurological deficit. Patients with simple epidural abscess without bony instability were treated with laminectomy and were not included in this series. Fourteen patients were treated with posterior-only decompression and long-segment rigid fixation, without formal debridement of the infected area. One patient was treated with staged anterior and posterior surgery due to delay in treatment related to medical comorbidities. The authors examined as their outcome the ambulatory status and recurrence of deep infection requiring additional surgery or medical treatment.
RESULTS: Of the initial 15 patients, 10 (66%) had a minimum 2-year follow-up and 14 patients had at least 1 year of followup. There were no recurrent spinal infections. There were 3 unplanned reoperations (1 for loss of fixation, 1 for early superficial wound infection, and 1 for epidural hematoma). Nine (60%) of 15 patients were nonambulatory at presentation. At final followup, 8 of 15 patients were independently ambulatory, 6 required an assistive device, and 1 remained nonambulatory.
CONCLUSIONS: Long-segment fixation, without formal debridement, resulted in resolution of spinal infection in all cases and in significant neurological recovery in almost all cases. This surgical technique, when combined with aggressive antibiotic therapy and a multidisciplinary team approach, is an effective way of managing serious spinal infections in a challenging patient population.

Entities:  

Keywords:  BMP = bone morphogenetic protein; de novo spinal infection; osteomyelitis; posterior spinal fixation; single stage procedure; spondylodiscitis

Mesh:

Year:  2014        PMID: 25081966     DOI: 10.3171/2014.6.FOCUS14142

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  13 in total

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Review 2.  [Spondylodiscitis : Current strategies for diagnosis and treatment].

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Journal:  Orthopade       Date:  2017-09       Impact factor: 1.087

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4.  Distribution of HIV-1 in the genomes of AIDS patients.

Authors:  L Tsyba; A V Rynditch; E Boeri; K Jabbari; G Bernardi
Journal:  Cell Mol Life Sci       Date:  2004-03       Impact factor: 9.261

Review 5.  Management of Pyogenic Spinal Infection, review of literature.

Authors:  Ahmed Aljawadi; Noman Jahangir; Ana Jeelani; Zak Ferguson; Noman Niazi; Frances Arnall; Anand Pillai
Journal:  J Orthop       Date:  2019-08-12

6.  Medium-term outcome of posterior surgery in the treatment of non-tuberculous bacterial spinal infection.

Authors:  Ahmed Aljawadi; Gagan Sethi; Eze Imo; Frances Arnall; Muhammad Naghman Choudhry; Kuriakose Joshi George; Anant Tambe; Rajat Verma; Mohammed Naveed Yasin; Saeed Mohammed; Irfan Siddique
Journal:  J Orthop       Date:  2019-06-19

7.  Acute neck pain caused by septic arthritis of the lateral atlantoaxial joint with subluxation: a case report.

Authors:  Takashi Kobayashi; Naohisa Miyakoshi; Eiji Abe; Toshiki Abe; Kazuma Kikuchi; Yoichi Shimada
Journal:  J Med Case Rep       Date:  2015-08-15

8.  Vertebral osteomyelitis and epidural abscess caused by gas gangrene presenting with complete paraplegia: a case report.

Authors:  Manabu Akagawa; Takashi Kobayashi; Naohisa Miyakoshi; Eiji Abe; Toshiki Abe; Kazuma Kikuchi; Yoichi Shimada
Journal:  J Med Case Rep       Date:  2015-04-11

9.  Rigid Posterior Lumbopelvic Fixation without Formal Debridement for Pyogenic Vertebral Diskitis and Osteomyelitis Involving the Lumbosacral Junction: Technical Report.

Authors:  Marcus D Mazur; Vijay M Ravindra; Andrew T Dailey; Sara McEvoy; Meic H Schmidt
Journal:  Front Surg       Date:  2015-09-22

10.  Posterior Titanium Screw Fixation without Debridement of Infected Tissue for the Treatment of Thoracolumbar Spontaneous Pyogenic Spondylodiscitis.

Authors:  Mauro Dobran; Maurizio Iacoangeli; Davide Nasi; Niccolo Nocchi; Alessandro Di Rienzo; Lucia di Somma; Roberto Colasanti; Carmela Vaira; Roberta Benigni; Valentina Liverotti; Massimo Scerrati
Journal:  Asian Spine J       Date:  2016-06-16
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