Literature DB >> 28589391

[Spondylodiscitis : Current strategies for diagnosis and treatment].

I Michiels1, M Jäger2.   

Abstract

Spondylodiscitis is a severe infectious disease of the intervertebral discs and of the adjacent parts of the vertebral bodies, culminating in destruction of the mobile segment. It is accompanied by a mortality rate of approximately 15%. Severe courses of the disease can also lead to abscess formation and dispersal of sepsis. Malpositioning of the axis organ and deficits in neurological function up to paraplegia are also possible complications. Timely diagnostics and targeted therapy contribute to minimizing the risk of significant health disorders. This review article gives a summary of important algorithms in the diagnostics and treatment and discusses them against the background of currently available literature. According to the current state of knowledge the surgical treatment of spondylodiscitis provides many advantages and is therefore the method choice, even if a conservative approach can be successful in selected cases. The endpoints of treatment are cleansing of the infection with normalization of laboratory parameters of inflammation and the osseous fusion of the mobile segment.

Entities:  

Keywords:  Epidural abscess; Infections; Intervertebral disc; Spinal column; Surgery

Mesh:

Year:  2017        PMID: 28589391     DOI: 10.1007/s00132-017-3436-0

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  40 in total

1.  [Standards of microbiological diagnostics of spondylodiscitis].

Authors:  B Lehner; M Akbar; C Rehnitz; G W Omlor; U Dapunt; I Burckhardt
Journal:  Orthopade       Date:  2012-09       Impact factor: 1.087

2.  Introduction: vertebral osteomyelitis and spinal epidural abscess.

Authors:  Patrick C Hsieh; John C Liu; Michael Y Wang
Journal:  Neurosurg Focus       Date:  2014-08       Impact factor: 4.047

3.  Pyogenic spinal infections and outcome according to the 36-item short form health survey.

Authors:  Chris Woertgen; Ralf Dirk Rothoerl; Carsten Englert; Carsten Neumann
Journal:  J Neurosurg Spine       Date:  2006-06

4.  Application of titanium and polyetheretherketone cages in the treatment of pyogenic spondylodiscitis.

Authors:  Markus Schomacher; Tobias Finger; Daniel Koeppen; Olaf Süss; Peter Vajkoczy; Stefan Kroppenstedt; Mario Cabraja
Journal:  Clin Neurol Neurosurg       Date:  2014-10-05       Impact factor: 1.876

5.  Failure modes in conservative and surgical management of infectious spondylodiscitis.

Authors:  Kestutis Valancius; Ebbe Stender Hansen; Kristian Høy; Peter Helmig; Bent Niedermann; Cody Bünger
Journal:  Eur Spine J       Date:  2012-12-18       Impact factor: 3.134

6.  Intramedullary spinal cord abscess and subsequent granuloma formation: a rare complication of vertebral osteomyelitis detected by diffusion-weighted magnetic resonance imaging.

Authors:  Noriyoshi Takebe; Koichi Iwasaki; Hirokuni Hashikata; Hiroki Toda
Journal:  Neurosurg Focus       Date:  2014-08       Impact factor: 4.047

7.  Bone morphogenetic protein-2 (BMP-2) in the treatment of pyogenic vertebral osteomyelitis.

Authors:  R Todd Allen; Yu-Po Lee; Elizabeth Stimson; Steven R Garfin
Journal:  Spine (Phila Pa 1976)       Date:  2007-12-15       Impact factor: 3.468

Review 8.  Minimally invasive percutaneous endoscopic discectomy and drainage for infectious spondylodiscitis.

Authors:  Tsai-Sheng Fu; Lih-Hui Chen; Wen-Jer Chen
Journal:  Biomed J       Date:  2013 Jul-Aug       Impact factor: 4.910

9.  Clinical characteristics and therapeutic outcomes of hematogenous vertebral osteomyelitis caused by methicillin-resistant Staphylococcus aureus.

Authors:  Ki-Ho Park; Yong Pil Chong; Sung-Han Kim; Sang-Oh Lee; Sang-Ho Choi; Mi Suk Lee; Jin-Yong Jeong; Jun Hee Woo; Yang Soo Kim
Journal:  J Infect       Date:  2013-07-31       Impact factor: 6.072

Review 10.  Burden of Surgical Site Infections Associated with Select Spine Operations and Involvement of Staphylococcus aureus.

Authors:  Harshila Patel; Hanane Khoury; Douglas Girgenti; Sharon Welner; Holly Yu
Journal:  Surg Infect (Larchmt)       Date:  2016-11-30       Impact factor: 2.150

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  3 in total

1.  [Chameleon spondylodiscitis : Challenge for geriatricians].

Authors:  Werner Hofmann
Journal:  Nervenarzt       Date:  2018-06       Impact factor: 1.214

2.  Non-specific spondylodiscitis: a new perspective for surgical treatment.

Authors:  Nicola Giampaolini; Massimo Berdini; Marco Rotini; Rosa Palmisani; Nicola Specchia; Monia Martiniani
Journal:  Eur Spine J       Date:  2022-01-15       Impact factor: 3.134

3.  [Chameleon spondylodiscitis : Challenge for geriatricians].

Authors:  Werner Hofmann
Journal:  Z Gerontol Geriatr       Date:  2017-10-10       Impact factor: 1.281

  3 in total

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