Kevin D Harkins1, R Adam Horch1,2, Mark D Does1,2,3,4. 1. Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA. 2. Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA. 3. Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee, USA. 4. Electrical Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Abstract
PURPOSE: To present a new method for localizing signal within a two-dimensional (2D) slice suitable for ultrashort echo time (UTE) imaging, called saturation-based UTE (sat-UTE). The new method digitally subtracts two acquisitions that are nonselectively excited with and without selective saturation of the slice of interest. METHODS: Sat-UTE was compared with half-pulse and double-half pulse excited UTE within phantoms, as well as 3D-UTE within ex vivo femur and in vivo tibia. Numerical simulations were also used to quantify the effects of slice profile broadening and signal component amplitudes for quantitative UTE. RESULTS: Sat-UTE is robust to suppress out-of-slice signal, and produces short T2 signal decay curves comparable to 3D-UTE, but has a lower signal to noise ratio efficiency compared with other slice-selective methods. CONCLUSION: The proposed method is useful for fast, quantitative evaluation of short T2 signals, and is insensitive to gradient performance.
PURPOSE: To present a new method for localizing signal within a two-dimensional (2D) slice suitable for ultrashort echo time (UTE) imaging, called saturation-based UTE (sat-UTE). The new method digitally subtracts two acquisitions that are nonselectively excited with and without selective saturation of the slice of interest. METHODS:Sat-UTE was compared with half-pulse and double-half pulse excited UTE within phantoms, as well as 3D-UTE within ex vivo femur and in vivo tibia. Numerical simulations were also used to quantify the effects of slice profile broadening and signal component amplitudes for quantitative UTE. RESULTS:Sat-UTE is robust to suppress out-of-slice signal, and produces short T2 signal decay curves comparable to 3D-UTE, but has a lower signal to noise ratio efficiency compared with other slice-selective methods. CONCLUSION: The proposed method is useful for fast, quantitative evaluation of short T2 signals, and is insensitive to gradient performance.
Authors: Mary Kate Manhard; R Adam Horch; Kevin D Harkins; Daniel F Gochberg; Jeffry S Nyman; Mark D Does Journal: Magn Reson Med Date: 2013-07-22 Impact factor: 4.668
Authors: Mary Kate Manhard; Kevin D Harkins; Daniel F Gochberg; Jeffry S Nyman; Mark D Does Journal: Magn Reson Med Date: 2017-01-16 Impact factor: 4.668
Authors: Axel J Krafft; Ralf B Loeffler; Ruitian Song; Aaryani Tipirneni-Sajja; M Beth McCarville; Matthew D Robson; Jane S Hankins; Claudia M Hillenbrand Journal: Magn Reson Med Date: 2017-01-16 Impact factor: 4.668
Authors: Aurea B Martins-Bach; Damien Bachasson; Ericky C A Araujo; Lucas Soustelle; Paulo Loureiro de Sousa; Yves Fromes; Pierre G Carlier Journal: Sci Rep Date: 2021-01-11 Impact factor: 4.379