| Literature DB >> 2504594 |
P Legrand1, G Fournier, A Buré, V Jarlier, M H Nicolas, D Decré, J Duval, A Philippon.
Abstract
In 210 strains of Enterobacteriaceae which were isolated in four hospitals and which showed reduced susceptibility to cefotaxime, high synergy was demonstrated between amoxicillin (20 micrograms) + clavulanate (10 micrograms) and cefotaxime (30 micrograms) using a simple double-disk test. Isoelectric focusing on gel and specific iodometric detection using ceftriaxone identified four extended broad-spectrum beta-lactamases (isoelectric points 7.6, 6.3, 7.0 and 5.9) produced by the strains.Entities:
Mesh:
Substances:
Year: 1989 PMID: 2504594 DOI: 10.1007/bf01967473
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN: 0934-9723 Impact factor: 3.267