| Literature DB >> 25026065 |
Eve E Weatherill1, Mark I Wallace2.
Abstract
Combining simultaneous single-molecule fluorescence measurements of ion channel conformational change with single-channel electrophysiology would enable a direct link between structure and function. Such methods would help us to create a truly molecular "movie" of how these important biomolecules work. Here we review past and recent progress toward this goal.Entities:
Keywords: artificial lipid bilayer; patch-clamp fluorometry; single-molecule fluorescence
Mesh:
Substances:
Year: 2014 PMID: 25026065 DOI: 10.1016/j.jmb.2014.07.007
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469